Wake Forest vs Louisville Football Odds

The Demon Deacons will play the Cardinals on Saturday, September 26th, 2026. The matchup takes place at L&N Federal Credit Union Stadium. Watch this exciting Week 4 matchup at 12:00 pm EDT. Check local listings for coverage on ESPN, Disney+.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


Bonus

Table of Contents

Key Matchup Stats

We're now well into the 2026 college football season. Week 4 action features a matchup between Wake Forest and Louisville taking place at L&N Federal Credit Union Stadium. The following are some key season stats to help you size up this game.

  • SportsBetting3.com Power Rankings - Wake Forest has a 95.33 conference power ranking for the 2026 season. The conference power ranking for Louisville is 98.00.
  • Away Wake Forest - Heading into Week 4, Wake Forest currently has a 1-0 record as an away team for the 2026 regular season. This ranks them 2nd in the ACC Conference for away team wins. Watch this stat carefully as the season progresses.
  • Home Louisville - Louisville has a 2-0 record as a home team. Looking ahead to this 2026 Week 4 matchup, they rank 2nd in the ACC Conference for home team wins. Like the Wake Forest away record and ranking, you should continually keep tabs on this stat.
  • Points Scored - For the 2026 season, Wake Forest ranks 9th (96) in the ACC Conference, with Louisville currently ranking 3rd (138) for points scored in the ACC Conference.
  • Points Against - Also in 2026, Wake Forest stands 3rd (85) in the ACC Conference for points scored by opponents in 2026. Louisville sits at 3rd (85) in the ACC Conference for points against in the 2026 season so far.
  • Team Records - Wake Forest has a 2-1 overall record for the 2026 regular season, with Louisville currently 2-1 for the 2026 NCAAF regular season.

Best Demon Deacons at Cardinals Odds


Best Point Spread Betting Odds
TBDTBD
Point Spread odds are updating, please check back soon.

Best Total Betting Odds
OverUnder
Total odds are updating, please check back soon.

Best Moneyline Betting Odds
TBDTBD
Moneyline odds are updating, please check back soon.

College Football Odds Example

College Football Odds and Outcomes Explained
Game Book

Wake Forest at Louisville Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds

Bet
Wake Forest
Louisville
9/26/26 12:00pm EDT
Pending

Recent Meetings Since 2022

Recent Meetings Since 2022
WeekGameResultMargin
2026
Week 4
Wake Forest vs Louisville
Saturday, September 26th, 2026
WAKE 30, LOU 27
L&N Federal Credit Union Stadium
Wake Forest by 3
2022
Week 9
Wake Forest vs Louisville
Saturday, October 29th, 2022
LOU 48, WAKE 21
Cardinal Stadium
Louisville by 27

Team Standings

2026-2027 College Football Regular Season Standings - Wake Forest, Louisville
Team Conf Conf% W L PF PA Home Away Strk
Louisville3-25.000432711923-11-1W2
#14 Wake Forest4-13.000612621362-14-0W4

Wake Forest & Louisville Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Wake Forest Championship Odds

No NCAA College Football Championship TM Wake Forest YR: futures available

Louisville Championship Odds

No NCAA College Football Championship TM Louisville YR: futures available

Wake Forest & Louisville Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2026-27 Wake Forest Games & Results
WeekMatchupDate & Result
Week 1Akron vs
Wake Forest
WAKE 38, AKR 16
Thursday, September 3rd, 2026
Week 2Wake Forest vs
Purdue
WAKE 38, PUR 36 (2OT)
Saturday, September 12th, 2026
Week 3Miami (FL) vs
Wake Forest
MIA 33, WAKE 20
Friday, September 18th, 2026
Week 4Wake Forest vs
Louisville
WAKE 30, LOU 27
Saturday, September 26th, 2026
Week 5Stanford vs
Wake Forest
WAKE 57, STAN 3
Saturday, October 3rd, 2026
Week 6Wake Forest vs
NC State
WAKE 38, NCSU 14
Saturday, October 10th, 2026
Week 7Wake Forest vs
California
WAKE 41, CAL 7
Saturday, October 17th, 2026
Week 9Virginia vs
Wake Forest
Saturday, October 31st, 2026
3:45 pm EDT
Week 10Merrimack College vs
Wake Forest
Saturday, November 7th, 2026
3:30 pm EST
Week 11Wake Forest vs
SMU
Saturday, November 14th, 2026
12:00 am EST
Week 12Wake Forest vs
Georgia Tech
Saturday, November 21st, 2026
12:00 am EST
Week 13Duke vs
Wake Forest
Saturday, November 28th, 2026
12:00 am EST


2026-27 Louisville Games & Results
WeekMatchupDate & Result
Week 1Louisville vs
Ole Miss
MISS 41, LOU 38
Sunday, September 6th, 2026
Week 2Villanova vs
Louisville
LOU 59, VILL 13
Friday, September 11th, 2026
Week 3SMU vs
Louisville
LOU 41, SMU 31
Saturday, September 19th, 2026
Week 4Wake Forest vs
Louisville
WAKE 30, LOU 27
Saturday, September 26th, 2026
Week 5Louisville vs
NC State
NCSU 31, LOU 28
Saturday, October 3rd, 2026
Week 6Florida State vs
Louisville
LOU 44, FSU 20
Friday, October 9th, 2026
Week 7Louisville vs
Syracuse
LOU 34, SYR 26
Saturday, October 17th, 2026
Week 9Stanford vs
Louisville
Saturday, October 31st, 2026
3:15 pm EDT
Week 10Louisville vs
Georgia Tech
Saturday, November 7th, 2026
7:30 pm EST
Week 11Louisville vs
North Carolina
Saturday, November 14th, 2026
12:00 am EST
Week 12Pittsburgh vs
Louisville
Saturday, November 21st, 2026
12:00 am EST
Week 13Louisville vs
Kentucky
Saturday, November 28th, 2026
12:00 am EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Wake Forest vs Louisville College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 26th, 2026 at 12:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Wake Forest vs Louisville Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Wake Forest vs Louisville Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other September 26, 2026 NCAAFB Games

Odds Preview 8243