Buffalo Bills vs Detroit Lions Odds

The Bills will play the Lions on Friday, August 13th, 2021, in the annual Preseason event. The matchup takes place at Ford Field - Detroit, MI. Check local listings for coverage on NFL NET.

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Recent Meetings Since 2017

WeekGameResultMargin
2022
Wk 12
Bills vs Lions
Thursday, November 24th, 2022

Ford Field - Detroit, MI
Tie
2021
Pre Wk 1
Bills vs Lions
Friday, August 13th, 2021
Preseason
BUF 16, DET 15
Ford Field - Detroit, MI
Bills by 1
2020
Pre Wk 4
Bills vs Lions
Thursday, September 3rd, 2020
Preseason
Canceled
Ford Field - Detroit, MI
Tie
2019
Pre Wk 3
Bills vs Lions
Friday, August 23rd, 2019
Preseason
BUF 24, DET 20
Ford Field - Detroit, MI
Bills by 4
2018
Wk 15
Lions vs Bills
Sunday, December 16th, 2018
BUF 14, DET 13
Highmark Stadium - Orchard Park, NY
Bills by 1
2017
Pre Wk 4
Lions vs Bills
Thursday, August 31st, 2017
Preseason
BUF 27, DET 17
Highmark Stadium - Orchard Park, NY
Bills by 10

Preseason Team Standings

2021 Preseason Standings
Team Conf Div W L T Pct Home Road Last 5
Buffalo Bills
0-0-0 0-0-0 3 0 0 1.000 1-0-0 2-0-0 3-0-0
Detroit Lions
0-0-0 0-0-0 0 3 0 0.000 0-2-0 0-1-0 0-3-0

Team Stats

Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 398 285
Total Offensive Yards 6493 4637
Total Rushing Yards 2209 1866
Total Passing Yards 4284 2771
Sacks 42 27
Field Goals 28 / 32 21 / 23
Touchdowns 57 32
Avg Time Of Possession 31:42 28:33
Turnover Ratio +8

Detroit Lions Team Stats
Stat Detroit Lions Opponents
Total 1st Downs 329 372
Total Offensive Yards 5484 6456
Total Rushing Yards 1886 2296
Total Passing Yards 3598 4160
Sacks 30 36
Field Goals 26 / 30 36 / 41
Touchdowns 35 52
Avg Time Of Possession 29:12 31:23
Turnover Ratio -4

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds
2023 Super Bowl Winner Odds

Team
BetRivers BetRivers
Buffalo Bills
Detroit Lions Futures Odds
2023 Super Bowl Winner Odds

Team
BetRivers BetRivers
Detroit Lions

2021 Buffalo Bills Games & Results

WeekMatchupDate & Time
Pre 1Bills vs
Lions
Preseason
BUF 16, DET 15
Friday, August 13th, 2021
Pre 2Bills vs
Bears
Preseason
BUF 41, CHI 15
Saturday, August 21st, 2021
Pre 3Packers vs
Bills
Preseason
BUF 19, GB 0
Saturday, August 28th, 2021
1Steelers vs
Bills
PIT 23, BUF 16
Sunday, September 12th, 2021
2Bills vs
Dolphins
BUF 35, MIA 0
Sunday, September 19th, 2021
3TBD vs
Bills
BUF 43, WSH 21
Sunday, September 26th, 2021
4Texans vs
Bills
BUF 40, HOU 0
Sunday, October 3rd, 2021
5Bills vs
Chiefs
BUF 38, KC 20
Sunday, October 10th, 2021
6Bills vs
Titans
TEN 34, BUF 31
Monday, October 18th, 2021
8Dolphins vs
Bills
BUF 26, MIA 11
Sunday, October 31st, 2021
9Bills vs
Jaguars
JAX 9, BUF 6
Sunday, November 7th, 2021
10Bills vs
Jets
BUF 45, NYJ 17
Sunday, November 14th, 2021
11Colts vs
Bills
IND 41, BUF 15
Sunday, November 21st, 2021
12Bills vs
Saints
BUF 31, NO 6
Thursday, November 25th, 2021
13Patriots vs
Bills
NE 14, BUF 10
Monday, December 6th, 2021
14Bills vs
Buccaneers
TB 33, BUF 27 (OT)
Sunday, December 12th, 2021
15Panthers vs
Bills
BUF 31, CAR 14
Sunday, December 19th, 2021
16Bills vs
Patriots
BUF 33, NE 21
Sunday, December 26th, 2021
17Bills
Bye Week
17Falcons vs
Bills
BUF 29, ATL 15
Sunday, January 2nd, 2022
18Jets vs
Bills
BUF 27, NYJ 10
Sunday, January 9th, 2022
Patriots vs
Bills
AFC Wild Card Playoffs
BUF 47, NE 17
Saturday, January 15th, 2022
Bills vs
Chiefs
AFC Divisional Playoffs
KC 42, BUF 36 (OT)
Sunday, January 23rd, 2022

2021 Detroit Lions Games & Results

WeekMatchupDate & Time
Pre 1Bills vs
Lions
Preseason
BUF 16, DET 15
Friday, August 13th, 2021
Pre 2Lions vs
Steelers
Preseason
PIT 26, DET 20
Saturday, August 21st, 2021
Pre 3Colts vs
Lions
Preseason
IND 27, DET 17
Friday, August 27th, 2021
149ers vs
Lions
SF 41, DET 33
Sunday, September 12th, 2021
2Lions vs
Packers
GB 35, DET 17
Monday, September 20th, 2021
3Ravens vs
Lions
BAL 19, DET 17
Sunday, September 26th, 2021
4Lions vs
Bears
CHI 24, DET 14
Sunday, October 3rd, 2021
5Lions vs
Vikings
MIN 19, DET 17
Sunday, October 10th, 2021
6Bengals vs
Lions
CIN 34, DET 11
Sunday, October 17th, 2021
7Lions vs
Rams
LAR 28, DET 19
Sunday, October 24th, 2021
8Eagles vs
Lions
PHI 44, DET 6
Sunday, October 31st, 2021
10Lions vs
Steelers
DET 16, PIT 16 (OT)
Sunday, November 14th, 2021
11Lions vs
Browns
CLE 13, DET 10
Sunday, November 21st, 2021
12Bears vs
Lions
CHI 16, DET 14
Thursday, November 25th, 2021
13Vikings vs
Lions
DET 29, MIN 27
Sunday, December 5th, 2021
14Lions vs
Broncos
DEN 38, DET 10
Sunday, December 12th, 2021
15Cardinals vs
Lions
DET 30, ARI 12
Sunday, December 19th, 2021
16Lions vs
Falcons
ATL 20, DET 16
Sunday, December 26th, 2021
17Lions vs
Seahawks
SEA 51, DET 29
Sunday, January 2nd, 2022
18Packers vs
Lions
DET 37, GB 30
Sunday, January 9th, 2022

Current NFL Matchup Lines

Next 10 NFL Matchups
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Game
BetRivers BetRivers
Play
Bills
Rams
9/08/22 8:20pm EDT
Saints
Falcons
9/11/22 1:00pm EDT
Jaguars
commanders
9/11/22 1:00pm EDT
Ravens
Jets
9/11/22 1:00pm EDT
Patriots
Dolphins
9/11/22 1:00pm EDT
Colts
Texans
9/11/22 1:00pm EDT
Eagles
Lions
9/11/22 1:00pm EDT
Steelers
Bengals
9/11/22 1:00pm EDT
49ers
Bears
9/11/22 1:00pm EDT
Browns
Panthers
9/11/22 1:00pm EDT
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