Buffalo Bills vs Detroit Lions Odds

The Bills will play the Lions on Friday, August 13th, 2021, in the annual Preseason event. The matchup takes place at Ford Field - Detroit, MI. Check local listings for coverage on NFL NET.

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**Point Spread**
Underdog	Favorite

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**Total**
Over	Under

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**Moneyline**
Underdog	Favorite

Moneyline odds are updating, please check back soon.

Recent Meetings Since 2017

Week	Game	Result	Margin
2022 Wk 12	Bills vs Lions Thursday, November 24th, 2022	Ford Field - Detroit, MI	Tie
2021 Pre Wk 1	Bills vs Lions Friday, August 13th, 2021 Preseason	BUF 16, DET 15 Ford Field - Detroit, MI	Bills by 1
2020 Pre Wk 4	Bills vs Lions Thursday, September 3rd, 2020 Preseason	Canceled Ford Field - Detroit, MI	Tie
2019 Pre Wk 3	Bills vs Lions Friday, August 23rd, 2019 Preseason	BUF 24, DET 20 Ford Field - Detroit, MI	Bills by 4
2018 Wk 15	Lions vs Bills Sunday, December 16th, 2018	BUF 14, DET 13 Highmark Stadium - Orchard Park, NY	Bills by 1
2017 Pre Wk 4	Lions vs Bills Thursday, August 31st, 2017 Preseason	BUF 27, DET 17 Highmark Stadium - Orchard Park, NY	Bills by 10

Preseason Team Standings

**2021 Preseason Standings**
Team	Conf	Div	W	L	T	Pct	Home	Road	Last 5
Buffalo Bills	0-0-0	0-0-0	3	0	0	1.000	1-0-0	2-0-0	3-0-0
Detroit Lions	0-0-0	0-0-0	0	3	0	0.000	0-2-0	0-1-0	0-3-0

Team Stats

**Buffalo Bills Team Stats**
Stat	Buffalo Bills	Opponents
Total 1st Downs	398	285
Total Offensive Yards	6493	4637
Total Rushing Yards	2209	1866
Total Passing Yards	4284	2771
Sacks	42	27
Field Goals	28 / 32	21 / 23
Touchdowns	57	32
Avg Time Of Possession	31:42	28:33
Turnover Ratio	+8

**Detroit Lions Team Stats**
Stat	Detroit Lions	Opponents
Total 1st Downs	329	372
Total Offensive Yards	5484	6456
Total Rushing Yards	1886	2296
Total Passing Yards	3598	4160
Sacks	30	36
Field Goals	26 / 30	36 / 41
Touchdowns	35	52
Avg Time Of Possession	29:12	31:23
Turnover Ratio	-4

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds

2023 Super Bowl Winner Odds
Team	BetRivers
Buffalo Bills	+650 Play

Detroit Lions Futures Odds

2023 Super Bowl Winner Odds
Team	BetRivers
Detroit Lions	+12500 Play

2021 Buffalo Bills Games & Results

Week	Matchup	Date & Time
Pre 1	Bills vs Lions Preseason	BUF 16, DET 15 Friday, August 13th, 2021
Pre 2	Bills vs Bears Preseason	BUF 41, CHI 15 Saturday, August 21st, 2021
Pre 3	Packers vs Bills Preseason	BUF 19, GB 0 Saturday, August 28th, 2021
1	Steelers vs Bills	PIT 23, BUF 16 Sunday, September 12th, 2021
2	Bills vs Dolphins	BUF 35, MIA 0 Sunday, September 19th, 2021
3	TBD vs Bills	BUF 43, WSH 21 Sunday, September 26th, 2021
4	Texans vs Bills	BUF 40, HOU 0 Sunday, October 3rd, 2021
5	Bills vs Chiefs	BUF 38, KC 20 Sunday, October 10th, 2021
6	Bills vs Titans	TEN 34, BUF 31 Monday, October 18th, 2021
8	Dolphins vs Bills	BUF 26, MIA 11 Sunday, October 31st, 2021
9	Bills vs Jaguars	JAX 9, BUF 6 Sunday, November 7th, 2021
10	Bills vs Jets	BUF 45, NYJ 17 Sunday, November 14th, 2021
11	Colts vs Bills	IND 41, BUF 15 Sunday, November 21st, 2021
12	Bills vs Saints	BUF 31, NO 6 Thursday, November 25th, 2021
13	Patriots vs Bills	NE 14, BUF 10 Monday, December 6th, 2021
14	Bills vs Buccaneers	TB 33, BUF 27 (OT) Sunday, December 12th, 2021
15	Panthers vs Bills	BUF 31, CAR 14 Sunday, December 19th, 2021
16	Bills vs Patriots	BUF 33, NE 21 Sunday, December 26th, 2021
17	Bills Bye Week
17	Falcons vs Bills	BUF 29, ATL 15 Sunday, January 2nd, 2022
18	Jets vs Bills	BUF 27, NYJ 10 Sunday, January 9th, 2022
	Patriots vs Bills AFC Wild Card Playoffs	BUF 47, NE 17 Saturday, January 15th, 2022
	Bills vs Chiefs AFC Divisional Playoffs	KC 42, BUF 36 (OT) Sunday, January 23rd, 2022

2021 Detroit Lions Games & Results

Week	Matchup	Date & Time
Pre 1	Bills vs Lions Preseason	BUF 16, DET 15 Friday, August 13th, 2021
Pre 2	Lions vs Steelers Preseason	PIT 26, DET 20 Saturday, August 21st, 2021
Pre 3	Colts vs Lions Preseason	IND 27, DET 17 Friday, August 27th, 2021
1	49ers vs Lions	SF 41, DET 33 Sunday, September 12th, 2021
2	Lions vs Packers	GB 35, DET 17 Monday, September 20th, 2021
3	Ravens vs Lions	BAL 19, DET 17 Sunday, September 26th, 2021
4	Lions vs Bears	CHI 24, DET 14 Sunday, October 3rd, 2021
5	Lions vs Vikings	MIN 19, DET 17 Sunday, October 10th, 2021
6	Bengals vs Lions	CIN 34, DET 11 Sunday, October 17th, 2021
7	Lions vs Rams	LAR 28, DET 19 Sunday, October 24th, 2021
8	Eagles vs Lions	PHI 44, DET 6 Sunday, October 31st, 2021
10	Lions vs Steelers	DET 16, PIT 16 (OT) Sunday, November 14th, 2021
11	Lions vs Browns	CLE 13, DET 10 Sunday, November 21st, 2021
12	Bears vs Lions	CHI 16, DET 14 Thursday, November 25th, 2021
13	Vikings vs Lions	DET 29, MIN 27 Sunday, December 5th, 2021
14	Lions vs Broncos	DEN 38, DET 10 Sunday, December 12th, 2021
15	Cardinals vs Lions	DET 30, ARI 12 Sunday, December 19th, 2021
16	Lions vs Falcons	ATL 20, DET 16 Sunday, December 26th, 2021
17	Lions vs Seahawks	SEA 51, DET 29 Sunday, January 2nd, 2022
18	Packers vs Lions	DET 37, GB 30 Sunday, January 9th, 2022

Current NFL Matchup Lines

Next 10 NFL Matchups
+ Displays more odds
Game	BetRivers Play
Bills Rams 9/08/22 8:20pm EDT	+1 -117 -1 -105
Saints Falcons 9/11/22 1:00pm EDT	-5 -110 +5 -110
Jaguars commanders 9/11/22 1:00pm EDT	+4 -110 -4 -110
Ravens Jets 9/11/22 1:00pm EDT	-5.5 -110 +5.5 -110
Patriots Dolphins 9/11/22 1:00pm EDT	+2.5 -110 -2.5 -112
Colts Texans 9/11/22 1:00pm EDT	-8.5 -105 +8.5 -115
Eagles Lions 9/11/22 1:00pm EDT	-4 -110 +4 -110
Steelers Bengals 9/11/22 1:00pm EDT	+6.5 -110 -6.5 -110
49ers Bears 9/11/22 1:00pm EDT	-6.5 -110 +6.5 -110
Browns Panthers 9/11/22 1:00pm EDT	-2.5 -120 +2.5 -103

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