Buffalo Bills vs Detroit Lions NFL Betting Lines

Odds Preview 308

The Bills will play the Lions on Friday, August 13th, 2021. The matchup takes place at Ford Field. Watch this exciting week 18 matchup at 7:00 pm on NFL.

Best Underdog and Favorite Spread Bets
Underdog

Buffalo Bills
Favorite

Detroit Lions
+1.5 -105 Sb3gen1 -1.5 -115 Sb3gen1
+1.5 -105 Sb3gen2 -1.5 -115 Sb3gen2
SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Friday. Sb3gen1 has the best favorite Detroit Lions spread at -1.5 points. Sb3gen1 has the best underdog Buffalo Bills spread at +1.5 points.

Review our point spread betting tutorial and video for more information.
Best Over and Under Total Lines
OverUnder
36.5o -110 Sb3gen1 36.5u -110 Sb3gen1
36.5o -110 Sb3gen2 36.5u -110 Sb3gen2
The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 36.5 points laying $110 to win $100. Sb3gen1 has the best under line of 36.5 u -110.
Best Money Line Bets
Underdog

Buffalo Bills
Favorite

Detroit Lions
+110 Sb3gen2 -129 Sb3gen1
+109 Sb3gen1 -130 Sb3gen2
Here are money lines for the outright winner. Favorite Detroit Lions has a minus value. Lay $129 at Sb3gen1 to win $100. Underdog Buffalo Bills has a positive value. Risk $100 at Sb3gen2 to win $110.

Buffalo Bills vs Detroit Lions Prop Bets

The following prop bets are available for this matchup.

Super Bowl Odds

Latest Super Bowl odds, if available, for each team. Review odds for other teams and learn the best NFL bets here.

Buffalo Bills Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
Buffalo Bills

Cached 2021-09-26 21:08:57
Detroit Lions Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
Detroit Lions

Cached 2021-09-26 21:08:57

Team Stats

2021 Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 72 42
Total Offensive Yards 1166 758
Total Rushing Yards 382 224
Total Passing Yards 784 534
Sacks 9 4
Field Goals 6 / 7 3 / 3
Touchdowns 11 5
Avg Time Of Possession 32:26 27:33
Turnover Ratio +3

2021 Detroit Lions Team Stats
Stat Detroit Lions Opponents
Total 1st Downs 72 61
Total Offensive Yards 1059 1152
Total Rushing Yards 317 343
Total Passing Yards 742 809
Sacks 8 6
Field Goals 3 / 4 6 / 8
Touchdowns 8 11
Avg Time Of Possession 30:51 29:08
Turnover Ratio


Team Standings

2021 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
Buffalo Bills 1-1-0 1-0-0 2 1 0 0.667 1-1-0 1-0-0 2-1-0
Detroit Lions 0-2-0 0-1-0 0 3 0 0.000 0-2-0 0-1-0 0-3-0

2021 Buffalo Bills Games & Results

Bye Week: 7
WeekMatchupDate & Time
1 Steelers vs
Bills
PIT 23, BUF 16
09/12/2021
2 Bills vs
Dolphins
BUF 35, MIA 0
09/19/2021
3 TBD vs
Bills
09/26/2021
1:00PM
4 Texans vs
Bills
10/03/2021
1:00PM
5 Bills vs
Chiefs
10/10/2021
8:20PM
6 Bills vs
Titans
10/18/2021
8:15PM
7Buffalo Bills ByeN/A
8 Dolphins vs
Bills
10/31/2021
1:00PM
9 Bills vs
Jaguars
11/07/2021
1:00PM
10 Bills vs
Jets
11/14/2021
1:00PM
11 Colts vs
Bills
11/21/2021
1:00PM
12 Bills vs
Saints
11/25/2021
8:20PM
13 Patriots vs
Bills
12/06/2021
8:15PM
14 Bills vs
Buccaneers
12/12/2021
4:25PM
15 Panthers vs
Bills
TBD
12/19/2021
16 Bills vs
Patriots
12/26/2021
1:00PM
17 Falcons vs
Bills
01/02/2022
1:00PM

2021 Detroit Lions Games & Results

Bye Week: 9
WeekMatchupDate & Time
1 49ers vs
Lions
SF 41, DET 33
09/12/2021
2 Lions vs
Packers
GB 35, DET 17
09/20/2021
3 Ravens vs
Lions
09/26/2021
1:00PM
4 Lions vs
Bears
10/03/2021
1:00PM
5 Lions vs
Vikings
10/10/2021
1:00PM
6 Bengals vs
Lions
10/17/2021
1:00PM
7 Lions vs
Rams
10/24/2021
4:05PM
8 Eagles vs
Lions
10/31/2021
1:00PM
9Detroit Lions ByeN/A
10 Lions vs
Steelers
11/14/2021
1:00PM
11 Lions vs
Browns
11/21/2021
1:00PM
12 Bears vs
Lions
11/25/2021
12:30PM
13 Vikings vs
Lions
12/05/2021
1:00PM
14 Lions vs
Broncos
12/12/2021
4:05PM
15 Cardinals vs
Lions
12/19/2021
1:00PM
16 Lions vs
Falcons
12/26/2021
1:00PM
17 Lions vs
Seahawks
01/02/2022
4:25PM

Other 2021 Week 18 Matchups

MatchupDate & Time
TBD vs
Patriots
08/12/2021
7:30PM
Steelers vs
Eagles
08/12/2021
7:30PM
Titans vs
Falcons
08/13/2021
7:00PM
Bills vs
Lions
08/13/2021
7:00PM
Saints vs
Falcons
01/09/2022
1:00PM
Jets vs
Bills
01/09/2022
1:00PM
Bengals vs
Browns
01/09/2022
1:00PM
Packers vs
Lions
01/09/2022
1:00PM
Patriots vs
Dolphins
01/09/2022
1:00PM
Bears vs
Vikings
01/09/2022
1:00PM
TBD vs
Giants
01/09/2022
1:00PM
Cowboys vs
Eagles
01/09/2022
1:00PM
Panthers vs
Buccaneers
01/09/2022
1:00PM
Colts vs
Jaguars
01/09/2022
1:00PM
Steelers vs
Ravens
01/09/2022
1:00PM
Titans vs
Texans
01/09/2022
1:00PM
Chiefs vs
Broncos
01/09/2022
4:25PM
Chargers vs
Raiders
01/09/2022
4:25PM
49ers vs
Rams
01/09/2022
4:25PM
Seahawks vs
Cardinals
01/09/2022
4:25PM