Buffalo Bills vs Houston Texans Odds

The Bills will play the Texans on Thursday, November 20th, 2025. The matchup takes place at NRG Stadium. Watch this exciting Week 12 matchup at 8:15 pm EST. Check local listings for coverage on Prime Video.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Key Matchup Stats

Rolling into Week 12, the Buffalo Bills and Houston Texans will matchup on Thursday, November 20th, 2025 at NRG Stadium for an important mid-season game. We've compiled some key performance stats below to help you handicap this matchup. Now that the 2025-26 NFL regular season is half over, teams need to sharpen their performance with an eye for the January playoffs.

  • SportsBetting3.com Power Rankings - As of Week 12 of the 2025-26 season, the Buffalo Bills have a power ranking of 95.33. Our formula has the Houston Texans at a 93.67 power ranking.
  • Away Buffalo Bills - With the season now half over, the Buffalo Bills have a 2-2-0 record as an away team, ranking them 4th in the league for away team wins.
  • Home Houston Texans - The Houston Texans start this Week 12 matchup with a 3-2-0 record as a home team. They rank 4th in the league for home team wins so far in the 2025-26 regular season.
  • Points Scored - The Buffalo Bills currently rank 2nd (292) looking at Week 12, with the Houston Texans ranked 17th (220) for points scored to date.
  • Points Against - The Buffalo Bills stand 16th (229) now halfway through the regular season for points against. Meanwhile the Houston Texans currently rank 27th (163) for points against.
  • Team Records - The second half of the season is make or break. Heading into Week 12, the Buffalo Bills have a 7-3-0 record, with the Houston Texans at 5-5-0 for the 2025-26 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye! The Buffalo Bills clash with the Houston Texans in Week 12.

The season be half over, with the Bills standin' at 7-3-0 and the Texans at 5-5-0.

The battle be at NRG Stadium, in the heart o' Houston's vibrant city.

Buffalo be rated 95.33 in the Power Rankings while Houston be at 93.67. I recommend betting on this game at BetRivers, or BetMGM. Review this matchup's prop bets below, and look at the odds from our partner sportsbooks. May the best team prevail!

Best Bills at Texans Odds


Best Point Spread Betting Odds
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Best Total Betting Odds
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Buffalo Bills at Houston Texans Prop Bets

NFL Prop Bets
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Bills
Texans
11/20/25 8:15pm EST
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Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2025
Week 12
Bills vs Texans
Thursday, November 20th, 2025
HOU 23, BUF 19
NRG Stadium
Texans by 4
2024
Week 5
Bills vs Texans
Sunday, October 6th, 2024
HOU 23, BUF 20
NRG Stadium
Texans by 3
2021
Week 4
Texans vs Bills
Sunday, October 3rd, 2021
BUF 40, HOU 0
Highmark Stadium
Bills by 40

Team Standings

2025-2026 NFL Regular Season Standings - Buffalo Bills, Houston Texans
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xy - Buffalo Bills12500.7064813657-2-05-3-04-2-00.6679-3-00.7501W4-1-0
xy - Houston Texans12500.7064042957-2-05-3-05-1-00.83310-2-00.8339W5-0-0

Buffalo Bills & Houston Texans Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds

No Super Bowl TM Buffalo Bills YR: futures available

Houston Texans Futures Odds

No Super Bowl TM Houston Texans YR: futures available

Buffalo Bills & Houston Texans Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

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How to Bet on the Buffalo Bills vs Houston Texans NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, November 20th, 2025 at 8:15 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Buffalo Bills vs Houston Texans Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Buffalo Bills vs Houston Texans Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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