The Bills will play the Texans on Thursday, November 20th, 2025. The matchup takes place at NRG Stadium. Watch this exciting Week 12 matchup at 8:15 pm EST. Check local listings for coverage on Prime Video.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
Rolling into Week 12, the Buffalo Bills and Houston Texans will matchup on Thursday, November 20th, 2025 at NRG Stadium for an important mid-season game. We've compiled some key performance stats below to help you handicap this matchup. Now that the 2025-26 NFL regular season is half over, teams need to sharpen their performance with an eye for the January playoffs.
- SportsBetting3.com Power Rankings - As of Week 12 of the 2025-26 season, the Buffalo Bills have a power ranking of 95.33. Our formula has the Houston Texans at a 93.67 power ranking.
- Away Buffalo Bills - With the season now half over, the Buffalo Bills have a 2-2-0 record as an away team, ranking them 4th in the league for away team wins.
- Home Houston Texans - The Houston Texans start this Week 12 matchup with a 3-2-0 record as a home team. They rank 4th in the league for home team wins so far in the 2025-26 regular season.
- Points Scored - The Buffalo Bills currently rank 2nd (292) looking at Week 12, with the Houston Texans ranked 17th (220) for points scored to date.
- Points Against - The Buffalo Bills stand 16th (229) now halfway through the regular season for points against. Meanwhile the Houston Texans currently rank 27th (163) for points against.
- Team Records - The second half of the season is make or break. Heading into Week 12, the Buffalo Bills have a 7-3-0 record, with the Houston Texans at 5-5-0 for the 2025-26 regular season.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye! The Buffalo Bills clash with the Houston Texans in Week 12.
The season be half over, with the Bills standin' at 7-3-0 and the Texans at 5-5-0.
The battle be at NRG Stadium, in the heart o' Houston's vibrant city.
Buffalo be rated 95.33 in the Power Rankings while Houston be at 93.67. I recommend betting on this game at BetRivers, or BetMGM. Review this matchup's prop bets below, and look at the odds from our partner sportsbooks. May the best team prevail!
Best Bills at Texans Odds
| Underdog Houston Texans | Favorite Buffalo Bills |
|---|---|
| Over | Under |
|---|---|
| Underdog Houston Texans | Favorite Buffalo Bills |
|---|---|
Matchup Odds FAQs
The Buffalo Bills are -5.5 -115 point spread favorites at BetRivers, while the Houston Texans are +5.5 -108 point spread underdogs at BetRivers.
The best over line is 44 -114 points at BetRivers, which means you risk $114 to win $100 betting the over. The best under line is 44 -109 points at BetRivers, and that means you risk $109 to win $100 betting the under.
The Buffalo Bills are the -278 moneyline favorite at BetRivers and the Houston Texans are the +215 moneyline underdog at BetRivers.
NFL Odds Example
|
Game |
 BetRiversBet |
|---|---|
Bills
Texans
11/20/25 8:15pm EST | -5.5 -115+5.5 -108 |
Underdog Houston Texans - Houston Texans bettors risk $100 to win $92.59 at -108 odds.
A +5.5 Houston Texans underdog bet wins if they lose by 5 or fewer, tie, or win outright. Your bet loses if they lose by 6 or more.
Favorite Buffalo Bills - Buffalo Bills bettors risk $100 to win $86.96 at -115 odds.
A -5.5 Buffalo Bills favorite bet wins if they win by 6 or more. Your bet loses if they win by 5 or fewer, tie, or lose outright.
Buffalo Bills at Houston Texans Prop Bets
| BetRivers Bet |
|
|---|---|
Bills
Texans
First Field Goal
11/20/25 8:15pm EST | -103-129Bet |
Bills
Texans
First Team To Score
11/20/25 8:15pm EST | -143+112Bet |
Bills
Texans
Tie
First to 15 Points
11/20/25 8:15pm EST | -200+160+1400Bet |
Bills
Texans
Tie
First to 20 Points
11/20/25 8:15pm EST | -175+215+480Bet |
| BetRivers | |
Bills
Texans
Safety to be Scored
11/20/25 8:15pm EST | Yes +1150No -2500Bet |
Bills
Team Total Points
BUF at HOU 11/20/25 8:15pm EST | 24.5 o -10524.5 u -117Bet |
Texans
Team Total Points
BUF at HOU 11/20/25 8:15pm EST | 19.5 o -11319.5 u -108Bet |
Davis Mills
Interceptions Thrown
BUF at HOU 11/20/25 8:15pm EST | 0.5 o -1220.5 u -108Bet |
| BetRivers | |
Josh Allen
Interceptions Thrown
BUF at HOU 11/20/25 8:15pm EST | 0.5 o -1150.5 u -115Bet |
Davis Mills
Total Passing Yards
BUF at HOU 11/20/25 8:15pm EST | 210.5 o -114210.5 u -115Bet |
Josh Allen
Total Passing Yards
BUF at HOU 11/20/25 8:15pm EST | 220.5 o -115220.5 u -115Bet |
Davis Mills
Total Touchdown Passes
BUF at HOU 11/20/25 8:15pm EST | 1.5 o +1301.5 u -175Bet |
| BetRivers | |
Josh Allen
Total Touchdown Passes
BUF at HOU 11/20/25 8:15pm EST | 1.5 o +1121.5 u -148Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 12 | Bills vs Texans Thursday, November 20th, 2025 | HOU 23, BUF 19 NRG Stadium | Texans by 4 |
| 2024 Week 5 | Bills vs Texans Sunday, October 6th, 2024 | HOU 23, BUF 20 NRG Stadium | Texans by 3 |
| 2021 Week 4 | Texans vs Bills Sunday, October 3rd, 2021 | BUF 40, HOU 0 Highmark Stadium | Bills by 40 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| xy - Buffalo Bills | 12 | 5 | 0 | 0.706 | 481 | 365 | 7-2-0 | 5-3-0 | 4-2-0 | 0.667 | 9-3-0 | 0.750 | 1W | 4-1-0 |
| xy - Houston Texans | 12 | 5 | 0 | 0.706 | 404 | 295 | 7-2-0 | 5-3-0 | 5-1-0 | 0.833 | 10-2-0 | 0.833 | 9W | 5-0-0 |
Buffalo Bills & Houston Texans Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Buffalo Bills Futures Odds|
Team | BetRivers |
|---|---|
| Bills | +1000 Bet |
|
Team | BetRivers |
|---|---|
| Texans | +1800 Bet |
Buffalo Bills & Houston Texans Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Buffalo Bills vs Houston Texans NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, November 20th, 2025 at 8:15 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Buffalo Bills vs Houston Texans Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Buffalo Bills vs Houston Texans Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.