Buffalo Bills vs Kansas City Chiefs Odds

The Bills will play the Chiefs on Sunday, October 16th, 2022. The matchup takes place at GEHA Field at Arrowhead Stadium. Watch this exciting Week 6 matchup at 4:25 pm EDT. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props. Read the following to understand point spread betting.

BOOK
Bonus
BetRivers Sportsbook#1 BetRivers
REVIEW
$250 Bonus - 100% Match on First Deposit - Code: 250MATCH
Bet Now
21+ Playable in VA only
Gambling Problem? Call 1-888-532-3500
BetMGM Sportsbook#2 BetMGM
REVIEW
New Customers - Risk-Free First Bet Up to $1000
Bet Now
21+ Playable in VA only
Gambling Problem? Call 1-888-532-3500

Point Spread
Underdog

Kansas City Chiefs
Favorite

Buffalo Bills
SportsBetting3.com has analyzed the latest lines. Review our "Point Spread" table above to smash the books. BetMGM VA has the best favorite Buffalo Bills point spread at -2.5 points. BetRivers has the best underdog Kansas City Chiefs point spread at +3 points. Review our point spread betting tutorial and video for more information.

Total
OverUnder
The over under line estimates the combined total of each team's final score. BetRivers has the best over line of 54.5 points laying $108 to win $100. BetMGM has the best under line of 54.5 points.

Moneyline
Underdog

Kansas City Chiefs
Favorite

Buffalo Bills
Here are money lines for the outright winner. Favorite Buffalo Bills has a minus value. Lay $145 to win $100 at BetMGM. Underdog Kansas City Chiefs has a positive value. Risk $100 at BetRivers to win $129.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetRivers BetRivers
Bet
Bills
Chiefs
10/16/22 4:25pm EDT
Bet $100 at BetRivers Virginia
21+ Playable in VA only
Gambling Problem? Call 1-888-532-3500

Underdog Kansas City Chiefs - Kansas City Chiefs bettors risk $100 to win $81.97 at -122 odds.

A +3 Kansas City Chiefs underdog bet wins if they lose by 2 or fewer, tie, or win outright. The bet pushes if they lose by 3. Your bet loses if they lose by 4 or more.

Favorite Buffalo Bills - Buffalo Bills bettors risk $100 to win $102 at +102 odds.

A -3 Buffalo Bills favorite bet wins if they win by 4 or more. The bet pushes if they win by 3. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Buffalo Bills at Kansas City Chiefs Prop Bets

NFL Prop Bets
+ Displays more odds
BetRivers BetRivers
Bet
Bills
Chiefs
First Team To Score
10/16/22 4:25pm EDT
Bet
Bills
Chiefs
Tie
First to 15 Points
10/16/22 4:25pm EDT
Bet
Bills
Chiefs
Tie
First to 20 Points
10/16/22 4:25pm EDT
Bet

Recent Meetings Since 2018

WeekGameResultMargin
2022
Week 6
Bills vs Chiefs
Sunday, October 16th, 2022
BUF 24, KC 20
GEHA Field at Arrowhead Stadium
Bills by 4
2021
Divisional Round
Bills vs Chiefs
Sunday, January 23rd, 2022
AFC Divisional Playoffs
KC 42, BUF 36 (OT)
GEHA Field at Arrowhead Stadium
Chiefs by 6
2021
Week 5
Bills vs Chiefs
Sunday, October 10th, 2021
BUF 38, KC 20
GEHA Field at Arrowhead Stadium
Bills by 18
2020
Conference Championship
Bills vs Chiefs
Sunday, January 24th, 2021
AFC Championship
KC 38, BUF 24
GEHA Field at Arrowhead Stadium
Chiefs by 14
2020
Week 6
Chiefs vs Bills
Monday, October 19th, 2020
KC 26, BUF 17
Highmark Stadium
Chiefs by 9

Regular Season Team Standings

2022 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
xz
Buffalo Bills
9-2-0 4-2-0 13 3 0 0.813 7-1-0 6-2-0 5-0-0
xz*
Kansas City Chiefs
9-3-0 6-0-0 14 3 0 0.824 7-1-0 7-2-0 5-0-0

Team Stats

Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 367 313
Total Offensive Yards 6361 5106
Total Rushing Yards 2232 1673
Total Passing Yards 4291 3433
Sacks 33 40
Field Goals 27 / 31 21 / 28
Touchdowns 53 32
Turnover Ratio 0

Kansas City Chiefs Team Stats
Stat Kansas City Chiefs Opponents
Total 1st Downs 408 337
Total Offensive Yards 7032 5579
Total Rushing Yards 1970 1823
Total Passing Yards 5250 3756
Sacks 26 55
Field Goals 21 / 28 23 / 25
Touchdowns 61 43
Turnover Ratio -3

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Buffalo Bills Season Win Total
2022 NFL Buffalo Bills Season Win Total
+ Displays more odds
BetRivers BetRivers
Bet
Bills
2022 Season Win Total
Kansas City Chiefs Season Win Total
2022 NFL Kansas City Chiefs Season Win Total
+ Displays more odds
BetRivers BetRivers
Bet
Chiefs
2022 Season Win Total

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds

No Super Bowl Winner TM Buffalo Bills YR: futures available

Kansas City Chiefs Futures Odds
2023 Kansas City Chiefs Super Bowl Winner Odds

Team
BetRivers BetRivers BetMGM BetMGM
Chiefs

2022 Buffalo Bills Games & Results

WeekMatchupDate & Time
Preseason 1Colts vs
Bills
BUF 27, IND 24
Saturday, August 13th, 2022
Preseason 2Broncos vs
Bills
BUF 42, DEN 15
Saturday, August 20th, 2022
Preseason 3Bills vs
Panthers
CAR 21, BUF 0
Friday, August 26th, 2022
Week 1Bills vs
Rams
BUF 31, LAR 10
Thursday, September 8th, 2022
Week 2Titans vs
Bills
BUF 41, TEN 7
Monday, September 19th, 2022
Week 3Bills vs
Dolphins
MIA 21, BUF 19
Sunday, September 25th, 2022
Week 4Bills vs
Ravens
BUF 23, BAL 20
Sunday, October 2nd, 2022
Week 5Steelers vs
Bills
BUF 38, PIT 3
Sunday, October 9th, 2022
Week 6Bills vs
Chiefs
BUF 24, KC 20
Sunday, October 16th, 2022
Week 7Bills
Bye Week
Week 8Packers vs
Bills
BUF 27, GB 17
Sunday, October 30th, 2022
Week 9Bills vs
Jets
NYJ 20, BUF 17
Sunday, November 6th, 2022
Week 10Vikings vs
Bills
MIN 33, BUF 30 (OT)
Sunday, November 13th, 2022
Week 11Browns vs
Bills
BUF 31, CLE 23
Sunday, November 20th, 2022
Week 12Bills vs
Lions
BUF 28, DET 25
Thursday, November 24th, 2022
Week 13Bills vs
Patriots
BUF 24, NE 10
Thursday, December 1st, 2022
Week 14Jets vs
Bills
BUF 20, NYJ 12
Sunday, December 11th, 2022
Week 15Dolphins vs
Bills
BUF 32, MIA 29
Saturday, December 17th, 2022
Week 16Bills vs
Bears
BUF 35, CHI 13
Saturday, December 24th, 2022
Week 17Bills vs
Bengals
Monday, January 2nd, 2023
8:30 pm EST
Week 18Patriots vs
Bills
BUF 35, NE 23
Sunday, January 8th, 2023
Wild CardDolphins vs
Bills
AFC Wild Card Playoffs
BUF 34, MIA 31
Sunday, January 15th, 2023
Divisional RoundBengals vs
Bills
AFC Divisional Playoffs
CIN 27, BUF 10
Sunday, January 22nd, 2023

2022 Kansas City Chiefs Games & Results

WeekMatchupDate & Time
Preseason 1Chiefs vs
Bears
CHI 19, KC 14
Saturday, August 13th, 2022
Preseason 2Commanders vs
Chiefs
KC 24, WSH 14
Saturday, August 20th, 2022
Preseason 3Packers vs
Chiefs
KC 17, GB 10
Thursday, August 25th, 2022
Week 1Chiefs vs
Cardinals
KC 44, ARI 21
Sunday, September 11th, 2022
Week 2Chargers vs
Chiefs
KC 27, LAC 24
Thursday, September 15th, 2022
Week 3Chiefs vs
Colts
IND 20, KC 17
Sunday, September 25th, 2022
Week 4Chiefs vs
Buccaneers
KC 41, TB 31
Sunday, October 2nd, 2022
Week 5Raiders vs
Chiefs
KC 30, LV 29
Monday, October 10th, 2022
Week 6Bills vs
Chiefs
BUF 24, KC 20
Sunday, October 16th, 2022
Week 7Chiefs vs
49ers
KC 44, SF 23
Sunday, October 23rd, 2022
Week 8Chiefs
Bye Week
Week 9Titans vs
Chiefs
KC 20, TEN 17 (OT)
Sunday, November 6th, 2022
Week 10Jaguars vs
Chiefs
KC 27, JAX 17
Sunday, November 13th, 2022
Week 11Chiefs vs
Chargers
KC 30, LAC 27
Sunday, November 20th, 2022
Week 12Rams vs
Chiefs
KC 26, LAR 10
Sunday, November 27th, 2022
Week 13Chiefs vs
Bengals
CIN 27, KC 24
Sunday, December 4th, 2022
Week 14Chiefs vs
Broncos
KC 34, DEN 28
Sunday, December 11th, 2022
Week 15Chiefs vs
Texans
KC 30, HOU 24 (OT)
Sunday, December 18th, 2022
Week 16Seahawks vs
Chiefs
KC 24, SEA 10
Saturday, December 24th, 2022
Week 17Broncos vs
Chiefs
KC 27, DEN 24
Sunday, January 1st, 2023
Week 18Chiefs vs
Raiders
KC 31, LV 13
Saturday, January 7th, 2023
Divisional RoundJaguars vs
Chiefs
AFC Divisional Playoffs
KC 27, JAX 20
Saturday, January 21st, 2023
Conference ChampionshipBengals vs
Chiefs
AFC Championship
KC 23, CIN 20
Sunday, January 29th, 2023
Super BowlChiefs vs
Eagles
Super Bowl LVII
Sunday, February 12th, 2023
6:30 pm EST

Other October 16, 2022 NFL Games

Matchup
San Francisco 49ers vs
Atlanta Falcons
Tampa Bay Buccaneers vs
Pittsburgh Steelers
Baltimore Ravens vs
New York Giants
Cincinnati Bengals vs
New Orleans Saints
Jacksonville Jaguars vs
Indianapolis Colts
New York Jets vs
Green Bay Packers
New England Patriots vs
Cleveland Browns
Minnesota Vikings vs
Miami Dolphins
Carolina Panthers vs
Los Angeles Rams
Arizona Cardinals vs
Seattle Seahawks
Dallas Cowboys vs
Philadelphia Eagles
Odds Preview 771