Buffalo Bills vs New Orleans Saints Odds

The Bills will play the Saints on Thursday, November 25th, 2021. The matchup takes place at Caesars Superdome. Watch this exciting Week 12 matchup at 8:20 pm EST. Check local listings for coverage on NBC.

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Game

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3:25pm EDT
TBD VA
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Recent Meetings Since 2017

WeekGameResultMargin
2021
Week 12
Bills vs Saints
Thursday, November 25th, 2021
BUF 31, NO 6
Caesars Superdome
Bills by 25
2017
Week 10
Saints vs Bills
Sunday, November 12th, 2017
NO 47, BUF 10
Highmark Stadium
Saints by 37

Regular Season Team Standings

2021 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
xz
Buffalo Bills
7-5-0 5-1-0 11 6 0 0.647 6-3-0 5-3-0 4-1-0
New Orleans Saints
7-5-0 4-2-0 9 8 0 0.529 3-5-0 6-3-0 4-1-0

Team Stats

Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 398 285
Total Offensive Yards 6493 4637
Total Rushing Yards 2209 1866
Total Passing Yards 4284 2771
Sacks 42 27
Field Goals 28 / 32 21 / 23
Touchdowns 57 32
Avg Time Of Possession 31:42 28:33
Turnover Ratio +8

New Orleans Saints Team Stats
Stat New Orleans Saints Opponents
Total 1st Downs 307 304
Total Offensive Yards 5177 5410
Total Rushing Yards 1991 1589
Total Passing Yards 3186 3821
Sacks 46 37
Field Goals 25 / 30 31 / 38
Touchdowns 43 35
Avg Time Of Possession 30:37 29:40
Turnover Ratio +7

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Buffalo Bills Season Win Total
2022 NFL Buffalo Bills Season Win Total
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Buffalo Bills
2022 Season Win Total
New Orleans Saints Season Win Total
2022 NFL New Orleans Saints Season Win Total
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New Orleans Saints
2022 Season Win Total

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds
2023 Super Bowl Winner Odds

Team
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Buffalo Bills
New Orleans Saints Futures Odds
2023 Super Bowl Winner Odds

Team
BetRivers BetRivers
New Orleans Saints

2021 Buffalo Bills Games & Results

WeekMatchupDate & Time
Preseason 1Bills vs
Lions
BUF 16, DET 15
Friday, August 13th, 2021
Preseason 2Bills vs
Bears
BUF 41, CHI 15
Saturday, August 21st, 2021
Preseason 3Packers vs
Bills
BUF 19, GB 0
Saturday, August 28th, 2021
Week 1Steelers vs
Bills
PIT 23, BUF 16
Sunday, September 12th, 2021
Week 2Bills vs
Dolphins
BUF 35, MIA 0
Sunday, September 19th, 2021
Week 3TBD vs
Bills
BUF 43, WSH 21
Sunday, September 26th, 2021
Week 4Texans vs
Bills
BUF 40, HOU 0
Sunday, October 3rd, 2021
Week 5Bills vs
Chiefs
BUF 38, KC 20
Sunday, October 10th, 2021
Week 6Bills vs
Titans
TEN 34, BUF 31
Monday, October 18th, 2021
Week 7Bills
Bye Week
Week 8Dolphins vs
Bills
BUF 26, MIA 11
Sunday, October 31st, 2021
Week 9Bills vs
Jaguars
JAX 9, BUF 6
Sunday, November 7th, 2021
Week 10Bills vs
Jets
BUF 45, NYJ 17
Sunday, November 14th, 2021
Week 11Colts vs
Bills
IND 41, BUF 15
Sunday, November 21st, 2021
Week 12Bills vs
Saints
BUF 31, NO 6
Thursday, November 25th, 2021
Week 13Patriots vs
Bills
NE 14, BUF 10
Monday, December 6th, 2021
Week 14Bills vs
Buccaneers
TB 33, BUF 27 (OT)
Sunday, December 12th, 2021
Week 15Panthers vs
Bills
BUF 31, CAR 14
Sunday, December 19th, 2021
Week 16Bills vs
Patriots
BUF 33, NE 21
Sunday, December 26th, 2021
Week 17Falcons vs
Bills
BUF 29, ATL 15
Sunday, January 2nd, 2022
Week 18Jets vs
Bills
BUF 27, NYJ 10
Sunday, January 9th, 2022
Wild CardPatriots vs
Bills
AFC Wild Card Playoffs
BUF 47, NE 17
Saturday, January 15th, 2022
Divisional RoundBills vs
Chiefs
AFC Divisional Playoffs
KC 42, BUF 36 (OT)
Sunday, January 23rd, 2022

2021 New Orleans Saints Games & Results

WeekMatchupDate & Time
Preseason 1Saints vs
Ravens
BAL 17, NO 14
Saturday, August 14th, 2021
Preseason 2Jaguars vs
Saints
NO 23, JAX 21
Monday, August 23rd, 2021
Preseason 3Cardinals vs
Saints
Saturday, August 28th, 2021
1:00 pm EDT
Week 1Packers vs
Saints
NO 38, GB 3
Sunday, September 12th, 2021
Week 2Saints vs
Panthers
CAR 26, NO 7
Sunday, September 19th, 2021
Week 3Saints vs
Patriots
NO 28, NE 13
Sunday, September 26th, 2021
Week 4Giants vs
Saints
NYG 27, NO 21 (OT)
Sunday, October 3rd, 2021
Week 5Saints vs
TBD
NO 33, WSH 22
Sunday, October 10th, 2021
Week 6Saints
Bye Week
Week 7Saints vs
Seahawks
NO 13, SEA 10
Monday, October 25th, 2021
Week 8Buccaneers vs
Saints
NO 36, TB 27
Sunday, October 31st, 2021
Week 9Falcons vs
Saints
ATL 27, NO 25
Sunday, November 7th, 2021
Week 10Saints vs
Titans
TEN 23, NO 21
Sunday, November 14th, 2021
Week 11Saints vs
Eagles
PHI 40, NO 29
Sunday, November 21st, 2021
Week 12Bills vs
Saints
BUF 31, NO 6
Thursday, November 25th, 2021
Week 13Cowboys vs
Saints
DAL 27, NO 17
Thursday, December 2nd, 2021
Week 14Saints vs
Jets
NO 30, NYJ 9
Sunday, December 12th, 2021
Week 15Saints vs
Buccaneers
NO 9, TB 0
Sunday, December 19th, 2021
Week 16Dolphins vs
Saints
MIA 20, NO 3
Monday, December 27th, 2021
Week 17Panthers vs
Saints
NO 18, CAR 10
Sunday, January 2nd, 2022
Week 18Saints vs
Falcons
NO 30, ATL 20
Sunday, January 9th, 2022

Current NFL Matchup Lines

Next 10 NFL Matchups
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Game
BetRivers BetRivers
Bet
Panthers
Patriots
7:00pm EDT
Saints
Packers
8:00pm EDT
Texans
Rams
10:00pm EDT
Broncos
Bills
8/20/22 1:00pm EDT
Lions
Colts
8/20/22 1:00pm EDT
Commanders
Chiefs
8/20/22 4:00pm EDT
Steelers
Jaguars
8/20/22 7:00pm EDT
Raiders
Dolphins
8/20/22 7:00pm EDT
49ers
Vikings
8/20/22 7:00pm EDT
Buccaneers
Titans
8/20/22 7:00pm EDT
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