Buffalo Bills vs San Francisco 49ers Odds

The Bills will play the 49ers on Monday, December 7th, 2020. The matchup takes place at State Farm Stadium - Glendale, AZ. Watch this exciting Week 13 matchup at 8:15 pm EST. Check local listings for coverage on ESPN, ABC.

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Recent Meetings Since 2016

WeekGameResultMargin
2020
Wk 13
Bills vs 49ers
Monday, December 7th, 2020
BUF 34, SF 24
State Farm Stadium - Glendale, AZ
Bills by 10
2016
Wk 6
49ers vs Bills
Sunday, October 16th, 2016
BUF 45, SF 16
Highmark Stadium - Orchard Park, NY
Bills by 29

Team Standings

2020 Standings
Team Conf Div W L T Pct Home Road Last 5
xz
Buffalo Bills
10-2-0 6-0-0 13 3 0 0.813 7-1-0 6-2-0 5-0-0
San Francisco 49ers
4-8-0 3-3-0 6 10 0 0.375 1-7-0 5-3-0 1-4-0

Team Stats

Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 397 351
Total Offensive Yards 6343 5640
Total Rushing Yards 1723 1914
Total Passing Yards 4620 3726
Sacks 38 27
Field Goals 28 / 34 23 / 25
Touchdowns 60 44
Avg Time Of Possession 31:45 28:14
Turnover Ratio +4

San Francisco 49ers Team Stats
Stat San Francisco 49ers Opponents
Total 1st Downs 350 311
Total Offensive Yards 5922 5030
Total Rushing Yards 1889 1703
Total Passing Yards 4033 3327
Sacks 30 39
Field Goals 22 / 26 33 / 37
Touchdowns 45 42
Avg Time Of Possession 31:23 28:36
Turnover Ratio -11

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Buffalo Bills Futures Odds
2023 Super Bowl Winner Odds

Team
BetRivers BetRivers
Buffalo Bills
San Francisco 49ers Futures Odds
2023 Super Bowl Winner Odds

Team
BetRivers BetRivers
San Francisco 49ers

2020 Buffalo Bills Games & Results

WeekMatchupDate & Time
Pre 1Bills vs
Ravens
Preseason
Canceled
Friday, August 14th, 2020
Pre 2Falcons vs
Bills
Preseason
Canceled
Friday, August 21st, 2020
Pre 3Colts vs
Bills
Preseason
Canceled
Saturday, August 29th, 2020
Pre 4Bills vs
Lions
Preseason
Canceled
Thursday, September 3rd, 2020
1Jets vs
Bills
BUF 27, NYJ 17
Sunday, September 13th, 2020
2Bills vs
Dolphins
BUF 31, MIA 28
Sunday, September 20th, 2020
3Rams vs
Bills
BUF 35, LAR 32
Sunday, September 27th, 2020
4Bills vs
Raiders
BUF 30, LV 23
Sunday, October 4th, 2020
5Bills vs
Titans
TEN 42, BUF 16
Tuesday, October 13th, 2020
6Chiefs vs
Bills
KC 26, BUF 17
Monday, October 19th, 2020
7Bills vs
Jets
BUF 18, NYJ 10
Sunday, October 25th, 2020
8Patriots vs
Bills
BUF 24, NE 21
Sunday, November 1st, 2020
9Seahawks vs
Bills
BUF 44, SEA 34
Sunday, November 8th, 2020
10Bills vs
Cardinals
ARI 32, BUF 30
Sunday, November 15th, 2020
12Chargers vs
Bills
BUF 27, LAC 17
Sunday, November 29th, 2020
13Bills vs
49ers
BUF 34, SF 24
Monday, December 7th, 2020
14Steelers vs
Bills
BUF 26, PIT 15
Sunday, December 13th, 2020
15Bills vs
Broncos
BUF 48, DEN 19
Saturday, December 19th, 2020
16Bills vs
Patriots
BUF 38, NE 9
Monday, December 28th, 2020
17Dolphins vs
Bills
BUF 56, MIA 26
Sunday, January 3rd, 2021
Colts vs
Bills
AFC Wild Card Playoffs
BUF 27, IND 24
Saturday, January 9th, 2021
Ravens vs
Bills
AFC Divisional Playoffs
BUF 17, BAL 3
Saturday, January 16th, 2021
Bills vs
Chiefs
AFC Championship
KC 38, BUF 24
Sunday, January 24th, 2021

2020 San Francisco 49ers Games & Results

WeekMatchupDate & Time
Pre 149ers vs
Broncos
Preseason
Canceled
Saturday, August 15th, 2020
Pre 2Raiders vs
49ers
Preseason
Canceled
Friday, August 21st, 2020
Pre 349ers vs
Bears
Preseason
Canceled
Saturday, August 29th, 2020
Pre 4Chargers vs
49ers
Preseason
Canceled
Thursday, September 3rd, 2020
1Cardinals vs
49ers
ARI 24, SF 20
Sunday, September 13th, 2020
249ers vs
Jets
SF 31, NYJ 13
Sunday, September 20th, 2020
349ers vs
Giants
SF 36, NYG 9
Sunday, September 27th, 2020
4Eagles vs
49ers
PHI 25, SF 20
Sunday, October 4th, 2020
5Dolphins vs
49ers
MIA 43, SF 17
Sunday, October 11th, 2020
6Rams vs
49ers
SF 24, LAR 16
Sunday, October 18th, 2020
749ers vs
Patriots
SF 33, NE 6
Sunday, October 25th, 2020
849ers vs
Seahawks
SEA 37, SF 27
Sunday, November 1st, 2020
9Packers vs
49ers
GB 34, SF 17
Thursday, November 5th, 2020
1049ers vs
Saints
NO 27, SF 13
Sunday, November 15th, 2020
1249ers vs
Rams
SF 23, LAR 20
Sunday, November 29th, 2020
13Bills vs
49ers
BUF 34, SF 24
Monday, December 7th, 2020
14TBD vs
49ers
WSH 23, SF 15
Sunday, December 13th, 2020
1549ers vs
Cowboys
DAL 41, SF 33
Sunday, December 20th, 2020
1649ers vs
Cardinals
SF 20, ARI 12
Saturday, December 26th, 2020
17Seahawks vs
49ers
SEA 26, SF 23
Sunday, January 3rd, 2021

Current NFL Matchup Lines

Next 10 NFL Matchups
+ Displays more odds

Game
BetRivers BetRivers
Play
Bills
Rams
9/08/22 8:20pm EDT
Saints
Falcons
9/11/22 1:00pm EDT
Jaguars
commanders
9/11/22 1:00pm EDT
Ravens
Jets
9/11/22 1:00pm EDT
Patriots
Dolphins
9/11/22 1:00pm EDT
Colts
Texans
9/11/22 1:00pm EDT
Eagles
Lions
9/11/22 1:00pm EDT
Steelers
Bengals
9/11/22 1:00pm EDT
49ers
Bears
9/11/22 1:00pm EDT
Browns
Panthers
9/11/22 1:00pm EDT
Odds Preview 159