Carolina Panthers vs Buffalo Bills Odds

The Panthers will play the Bills on Sunday, December 19th, 2021. The matchup takes place at Highmark Stadium. Watch this exciting Week 15 matchup at 1:00 pm EST. Check local listings for coverage on FOX.

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Carolina Panthers at Buffalo Bills Prop Bets

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12/19/21 1:00pm EST
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Recent Meetings Since 2017

WeekGameResultMargin
2021
Week 15
Panthers vs Bills
Sunday, December 19th, 2021
BUF 31, CAR 14
Highmark Stadium
Bills by 17
2019
Preseason Week 2
Bills vs Panthers
Friday, August 16th, 2019
BUF 27, CAR 14
Bank of America Stadium
Bills by 13
2018
Preseason Week 1
Panthers vs Bills
Thursday, August 9th, 2018
CAR 28, BUF 23
Highmark Stadium
Panthers by 5
2017
Week 2
Bills vs Panthers
Sunday, September 17th, 2017
CAR 9, BUF 3
Bank of America Stadium
Panthers by 6

Regular Season Team Standings

2021 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
Carolina Panthers
3-9-0 2-4-0 5 12 0 0.294 2-6-0 3-6-0 0-5-0
xz
Buffalo Bills
7-5-0 5-1-0 11 6 0 0.647 6-3-0 5-3-0 4-1-0

Team Stats

Carolina Panthers Team Stats
Stat Carolina Panthers Opponents
Total 1st Downs 322 311
Total Offensive Yards 5081 5201
Total Rushing Yards 1839 1935
Total Passing Yards 3573 3266
Sacks 52 39
Field Goals 26 / 29 32 / 37
Touchdowns 32 44
Turnover Ratio -13

Buffalo Bills Team Stats
Stat Buffalo Bills Opponents
Total 1st Downs 398 285
Total Offensive Yards 6493 4637
Total Rushing Yards 2209 1866
Total Passing Yards 4450 2771
Sacks 27 42
Field Goals 28 / 32 21 / 23
Touchdowns 57 31
Turnover Ratio 8

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Carolina Panthers Season Win Total
2022 NFL Carolina Panthers Season Win Total
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Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Carolina Panthers Futures Odds
2023 Carolina Panthers Super Bowl Winner Odds

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Buffalo Bills Futures Odds
2023 Buffalo Bills Super Bowl Winner Odds

Team
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2021 Carolina Panthers Games & Results

WeekMatchupDate & Time
Preseason 1Panthers vs
Colts
IND 21, CAR 18
Sunday, August 15th, 2021
Preseason 2Ravens vs
Panthers
BAL 20, CAR 3
Saturday, August 21st, 2021
Preseason 3Steelers vs
Panthers
CAR 34, PIT 9
Friday, August 27th, 2021
Week 1Jets vs
Panthers
CAR 19, NYJ 14
Sunday, September 12th, 2021
Week 2Saints vs
Panthers
CAR 26, NO 7
Sunday, September 19th, 2021
Week 3Panthers vs
Texans
CAR 24, HOU 9
Thursday, September 23rd, 2021
Week 4Panthers vs
Cowboys
DAL 36, CAR 28
Sunday, October 3rd, 2021
Week 5Eagles vs
Panthers
PHI 21, CAR 18
Sunday, October 10th, 2021
Week 6Vikings vs
Panthers
MIN 34, CAR 28 (OT)
Sunday, October 17th, 2021
Week 7Panthers vs
Giants
NYG 25, CAR 3
Sunday, October 24th, 2021
Week 8Panthers vs
Falcons
CAR 19, ATL 13
Sunday, October 31st, 2021
Week 9Patriots vs
Panthers
NE 24, CAR 6
Sunday, November 7th, 2021
Week 10Panthers vs
Cardinals
CAR 34, ARI 10
Sunday, November 14th, 2021
Week 11TBD vs
Panthers
WSH 27, CAR 21
Sunday, November 21st, 2021
Week 12Panthers vs
Dolphins
MIA 33, CAR 10
Sunday, November 28th, 2021
Week 13Panthers
Bye Week
Week 14Falcons vs
Panthers
ATL 29, CAR 21
Sunday, December 12th, 2021
Week 15Panthers vs
Bills
BUF 31, CAR 14
Sunday, December 19th, 2021
Week 16Buccaneers vs
Panthers
TB 32, CAR 6
Sunday, December 26th, 2021
Week 17Panthers vs
Saints
NO 18, CAR 10
Sunday, January 2nd, 2022
Week 18Panthers vs
Buccaneers
TB 41, CAR 17
Sunday, January 9th, 2022

2021 Buffalo Bills Games & Results

WeekMatchupDate & Time
Preseason 1Bills vs
Lions
BUF 16, DET 15
Friday, August 13th, 2021
Preseason 2Bills vs
Bears
BUF 41, CHI 15
Saturday, August 21st, 2021
Preseason 3Packers vs
Bills
BUF 19, GB 0
Saturday, August 28th, 2021
Week 1Steelers vs
Bills
PIT 23, BUF 16
Sunday, September 12th, 2021
Week 2Bills vs
Dolphins
BUF 35, MIA 0
Sunday, September 19th, 2021
Week 3TBD vs
Bills
BUF 43, WSH 21
Sunday, September 26th, 2021
Week 4Texans vs
Bills
BUF 40, HOU 0
Sunday, October 3rd, 2021
Week 5Bills vs
Chiefs
BUF 38, KC 20
Sunday, October 10th, 2021
Week 6Bills vs
Titans
TEN 34, BUF 31
Monday, October 18th, 2021
Week 7Bills
Bye Week
Week 8Dolphins vs
Bills
BUF 26, MIA 11
Sunday, October 31st, 2021
Week 9Bills vs
Jaguars
JAX 9, BUF 6
Sunday, November 7th, 2021
Week 10Bills vs
Jets
BUF 45, NYJ 17
Sunday, November 14th, 2021
Week 11Colts vs
Bills
IND 41, BUF 15
Sunday, November 21st, 2021
Week 12Bills vs
Saints
BUF 31, NO 6
Thursday, November 25th, 2021
Week 13Patriots vs
Bills
NE 14, BUF 10
Monday, December 6th, 2021
Week 14Bills vs
Buccaneers
TB 33, BUF 27 (OT)
Sunday, December 12th, 2021
Week 15Panthers vs
Bills
BUF 31, CAR 14
Sunday, December 19th, 2021
Week 16Bills vs
Patriots
BUF 33, NE 21
Sunday, December 26th, 2021
Week 17Falcons vs
Bills
BUF 29, ATL 15
Sunday, January 2nd, 2022
Week 18Jets vs
Bills
BUF 27, NYJ 10
Sunday, January 9th, 2022
Wild CardPatriots vs
Bills
AFC Wild Card Playoffs
BUF 47, NE 17
Saturday, January 15th, 2022
Divisional RoundBills vs
Chiefs
AFC Divisional Playoffs
KC 42, BUF 36 (OT)
Sunday, January 23rd, 2022

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