Indianapolis Colts vs Arizona Cardinals NFL Betting Lines

Odds Preview 563

The Colts will play the Cardinals on Saturday, December 25th, 2021. The matchup takes place at State Farm Stadium. Watch this exciting week 16 matchup at 8:15 pm on NFL NET.

Best Underdog and Favorite Spread Bets
Underdog

Indianapolis Colts
Favorite

Arizona Cardinals
+3 -103 Sb3gen1 -3 -105 Sb3gen3
+3 -105 Sb3gen2 -3 -115 Sb3gen2
+3 -115 Sb3gen3 -3 -117 Sb3gen1
SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Saturday. Sb3gen3 has the best favorite Arizona Cardinals spread at -3 points. Sb3gen1 has the best underdog Indianapolis Colts spread at +3 points.

Review our point spread betting tutorial and video for more information.
Best Over and Under Total Lines
OverUnder
48o -110 Sb3gen1 48u -110 Sb3gen1
48o -110 Sb3gen2 48u -110 Sb3gen2
48o -110 Sb3gen3 48u -110 Sb3gen3
The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 48 points laying $110 to win $100. Sb3gen1 has the best under line of 48 u -110.
Best Money Line Bets
Underdog

Indianapolis Colts
Favorite

Arizona Cardinals
+145 Sb3gen1 -165 Sb3gen1
+140 Sb3gen2 -165 Sb3gen2
+140 Sb3gen3 -170 Sb3gen3
Here are money lines for the outright winner. Favorite Arizona Cardinals has a minus value. Lay $165 at Sb3gen1 to win $100. Underdog Indianapolis Colts has a positive value. Risk $100 at Sb3gen1 to win $145.

Indianapolis Colts vs Arizona Cardinals Prop Bets

The following prop bets are available for this matchup.

Super Bowl Odds

Latest Super Bowl odds, if available, for each team. Review odds for other teams and learn the best NFL bets here.

Indianapolis Colts Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
Indianapolis Colts

Cached 2022-01-28 02:34:58
Arizona Cardinals Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
Arizona Cardinals

Cached 2022-01-28 02:34:58

Team Stats

2021 Indianapolis Colts Team Stats
Stat Indianapolis Colts Opponents
Total 1st Downs 354 334
Total Offensive Yards 5901 5834
Total Rushing Yards 2540 1854
Total Passing Yards 3361 3980
Sacks 33 32
Field Goals 29 / 35 22 / 27
Touchdowns 52 43
Avg Time Of Possession 32:03 28:33
Turnover Ratio +14

2021 Arizona Cardinals Team Stats
Stat Arizona Cardinals Opponents
Total 1st Downs 367 336
Total Offensive Yards 6352 5597
Total Rushing Yards 2076 1952
Total Passing Yards 4276 3645
Sacks 41 39
Field Goals 30 / 37 23 / 28
Touchdowns 52 42
Avg Time Of Possession 31:15 28:44
Turnover Ratio +12


Team Standings

2021 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
Indianapolis Colts
7-5-0 3-3-0 9 8 0 0.529 4-5-0 5-3-0 3-2-0
xy
Arizona Cardinals
7-5-0 4-2-0 11 6 0 0.647 3-5-0 8-1-0 1-4-0

2021 Indianapolis Colts Games & Results

Bye Week: 14
WeekMatchupDate & Time
1 Seahawks vs
Colts
SEA 28, IND 16
09/12/2021
2 Rams vs
Colts
LAR 27, IND 24
09/19/2021
3 Colts vs
Titans
TEN 25, IND 16
09/26/2021
4 Colts vs
Dolphins
IND 27, MIA 17
10/03/2021
5 Colts vs
Ravens
BAL 31, IND 25 (OT)
10/11/2021
6 Texans vs
Colts
IND 31, HOU 3
10/17/2021
7 Colts vs
49ers
IND 30, SF 18
10/24/2021
8 Titans vs
Colts
TEN 34, IND 31 (OT)
10/31/2021
9 Jets vs
Colts
IND 45, NYJ 30
11/04/2021
10 Jaguars vs
Colts
IND 23, JAX 17
11/14/2021
11 Colts vs
Bills
IND 41, BUF 15
11/21/2021
12 Buccaneers vs
Colts
TB 38, IND 31
11/28/2021
13 Colts vs
Texans
IND 31, HOU 0
12/05/2021
14Indianapolis Colts ByeN/A
15 Patriots vs
Colts
IND 27, NE 17
12/18/2021
16 Colts vs
Cardinals
IND 22, ARI 16
12/25/2021
17 Raiders vs
Colts
LV 23, IND 20
01/02/2022

2021 Arizona Cardinals Games & Results

Bye Week: 12
WeekMatchupDate & Time
1 Cardinals vs
Titans
ARI 38, TEN 13
09/12/2021
2 Vikings vs
Cardinals
ARI 34, MIN 33
09/19/2021
3 Cardinals vs
Jaguars
ARI 31, JAX 19
09/26/2021
4 Cardinals vs
Rams
ARI 37, LAR 20
10/03/2021
5 49ers vs
Cardinals
ARI 17, SF 10
10/10/2021
6 Cardinals vs
Browns
ARI 37, CLE 14
10/17/2021
7 Texans vs
Cardinals
ARI 31, HOU 5
10/24/2021
8 Packers vs
Cardinals
GB 24, ARI 21
10/28/2021
9 Cardinals vs
49ers
ARI 31, SF 17
11/07/2021
10 Panthers vs
Cardinals
CAR 34, ARI 10
11/14/2021
11 Cardinals vs
Seahawks
ARI 23, SEA 13
11/21/2021
12Arizona Cardinals ByeN/A
13 Cardinals vs
Bears
ARI 33, CHI 22
12/05/2021
14 Rams vs
Cardinals
LAR 30, ARI 23
12/13/2021
15 Cardinals vs
Lions
DET 30, ARI 12
12/19/2021
16 Colts vs
Cardinals
IND 22, ARI 16
12/25/2021
17 Cardinals vs
Cowboys
ARI 25, DAL 22
01/02/2022

Other 2021 Week 16 Matchups

MatchupDate & Time
49ers vs
Titans
TEN 20, SF 17
12/23/2021
Browns vs
Packers
GB 24, CLE 22
12/25/2021
Colts vs
Cardinals
IND 22, ARI 16
12/25/2021
Lions vs
Falcons
ATL 20, DET 16
12/26/2021
Ravens vs
Bengals
CIN 41, BAL 21
12/26/2021
Rams vs
Vikings
LAR 30, MIN 23
12/26/2021
Bills vs
Patriots
BUF 33, NE 21
12/26/2021
Jaguars vs
Jets
NYJ 26, JAX 21
12/26/2021
Giants vs
Eagles
PHI 34, NYG 10
12/26/2021
Buccaneers vs
Panthers
TB 32, CAR 6
12/26/2021
Chargers vs
Texans
HOU 41, LAC 29
12/26/2021
Bears vs
Seahawks
CHI 25, SEA 24
12/26/2021
Steelers vs
Chiefs
KC 36, PIT 10
12/26/2021
Broncos vs
Raiders
LV 17, DEN 13
12/26/2021
TBD vs
Cowboys
DAL 56, WSH 14
12/26/2021
Dolphins vs
Saints
MIA 20, NO 3
12/27/2021