The Colts will play the Bills on Sunday, November 21st, 2021. The matchup takes place at Highmark Stadium - Orchard Park, NY. Watch this exciting Week 11 matchup at 1:00 pm EST. Check local listings for coverage on CBS.
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Recent Meetings Since 2017
Week | Game | Result | Margin |
---|---|---|---|
2022 Pre Wk 1 | Colts vs Bills Saturday, August 13th, 2022 Preseason | Highmark Stadium - Orchard Park, NY | Tie |
2021 Wk 11 | Colts vs Bills Sunday, November 21st, 2021 | IND 41, BUF 15 Highmark Stadium - Orchard Park, NY | Colts by 26 |
2020 Wk wc | Colts vs Bills Saturday, January 9th, 2021 AFC Wild Card Playoffs | BUF 27, IND 24 Highmark Stadium - Orchard Park, NY | Bills by 3 |
2020 Pre Wk 3 | Colts vs Bills Saturday, August 29th, 2020 Preseason | Canceled Highmark Stadium - Orchard Park, NY | Tie |
2019 Pre Wk 1 | Colts vs Bills Thursday, August 8th, 2019 Preseason | BUF 24, IND 16 Highmark Stadium - Orchard Park, NY | Bills by 8 |
2018 Wk 7 | Bills vs Colts Sunday, October 21st, 2018 | IND 37, BUF 5 Lucas Oil Stadium - Indianapolis, IN | Colts by 32 |
2017 Wk 14 | Colts vs Bills Sunday, December 10th, 2017 | BUF 13, IND 7 (OT) Highmark Stadium - Orchard Park, NY | Bills by 6 |
Regular Season Team Standings
Team | Conf | Div | W | L | T | Pct | Home | Road | Last 5 |
---|---|---|---|---|---|---|---|---|---|
Indianapolis Colts | 7-5-0 | 3-3-0 | 9 | 8 | 0 | 0.529 | 4-5-0 | 5-3-0 | 3-2-0 |
xz Buffalo Bills | 7-5-0 | 5-1-0 | 11 | 6 | 0 | 0.647 | 6-3-0 | 5-3-0 | 4-1-0 |
Team Stats
Stat | Indianapolis Colts | Opponents |
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Total 1st Downs | 354 | 334 |
Total Offensive Yards | 5901 | 5834 |
Total Rushing Yards | 2540 | 1854 |
Total Passing Yards | 3361 | 3980 |
Sacks | 33 | 32 |
Field Goals | 29 / 35 | 22 / 27 |
Touchdowns | 52 | 43 |
Avg Time Of Possession | 32:03 | 28:33 |
Turnover Ratio | +14 |
Stat | Buffalo Bills | Opponents |
---|---|---|
Total 1st Downs | 398 | 285 |
Total Offensive Yards | 6493 | 4637 |
Total Rushing Yards | 2209 | 1866 |
Total Passing Yards | 4284 | 2771 |
Sacks | 42 | 27 |
Field Goals | 28 / 32 | 21 / 23 |
Touchdowns | 57 | 32 |
Avg Time Of Possession | 31:42 | 28:33 |
Turnover Ratio | +8 |
Team Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Indianapolis Colts Futures Odds
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Indianapolis Colts |
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Buffalo Bills |
2021 Indianapolis Colts Games & Results
Week | Matchup | Date & Time |
---|---|---|
Pre 1 | Panthers vs Colts Preseason | IND 21, CAR 18 Sunday, August 15th, 2021 |
Pre 2 | Colts vs Vikings Preseason | IND 12, MIN 10 Saturday, August 21st, 2021 |
Pre 3 | Colts vs Lions Preseason | IND 27, DET 17 Friday, August 27th, 2021 |
1 | Seahawks vs Colts | SEA 28, IND 16 Sunday, September 12th, 2021 |
2 | Rams vs Colts | LAR 27, IND 24 Sunday, September 19th, 2021 |
3 | Colts vs Titans | TEN 25, IND 16 Sunday, September 26th, 2021 |
4 | Colts vs Dolphins | IND 27, MIA 17 Sunday, October 3rd, 2021 |
5 | Colts vs Ravens | BAL 31, IND 25 (OT) Monday, October 11th, 2021 |
6 | Texans vs Colts | IND 31, HOU 3 Sunday, October 17th, 2021 |
7 | Colts vs 49ers | IND 30, SF 18 Sunday, October 24th, 2021 |
8 | Titans vs Colts | TEN 34, IND 31 (OT) Sunday, October 31st, 2021 |
9 | Jets vs Colts | IND 45, NYJ 30 Thursday, November 4th, 2021 |
10 | Jaguars vs Colts | IND 23, JAX 17 Sunday, November 14th, 2021 |
11 | Colts vs Bills | IND 41, BUF 15 Sunday, November 21st, 2021 |
12 | Buccaneers vs Colts | TB 38, IND 31 Sunday, November 28th, 2021 |
13 | Colts vs Texans | IND 31, HOU 0 Sunday, December 5th, 2021 |
15 | Patriots vs Colts | IND 27, NE 17 Saturday, December 18th, 2021 |
16 | Colts vs Cardinals | IND 22, ARI 16 Saturday, December 25th, 2021 |
17 | Raiders vs Colts | LV 23, IND 20 Sunday, January 2nd, 2022 |
18 | Colts vs Jaguars | JAX 26, IND 11 Sunday, January 9th, 2022 |
2021 Buffalo Bills Games & Results
Week | Matchup | Date & Time |
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Pre 1 | Bills vs Lions Preseason | BUF 16, DET 15 Friday, August 13th, 2021 |
Pre 2 | Bills vs Bears Preseason | BUF 41, CHI 15 Saturday, August 21st, 2021 |
Pre 3 | Packers vs Bills Preseason | BUF 19, GB 0 Saturday, August 28th, 2021 |
1 | Steelers vs Bills | PIT 23, BUF 16 Sunday, September 12th, 2021 |
2 | Bills vs Dolphins | BUF 35, MIA 0 Sunday, September 19th, 2021 |
3 | TBD vs Bills | BUF 43, WSH 21 Sunday, September 26th, 2021 |
4 | Texans vs Bills | BUF 40, HOU 0 Sunday, October 3rd, 2021 |
5 | Bills vs Chiefs | BUF 38, KC 20 Sunday, October 10th, 2021 |
6 | Bills vs Titans | TEN 34, BUF 31 Monday, October 18th, 2021 |
8 | Dolphins vs Bills | BUF 26, MIA 11 Sunday, October 31st, 2021 |
9 | Bills vs Jaguars | JAX 9, BUF 6 Sunday, November 7th, 2021 |
10 | Bills vs Jets | BUF 45, NYJ 17 Sunday, November 14th, 2021 |
11 | Colts vs Bills | IND 41, BUF 15 Sunday, November 21st, 2021 |
12 | Bills vs Saints | BUF 31, NO 6 Thursday, November 25th, 2021 |
13 | Patriots vs Bills | NE 14, BUF 10 Monday, December 6th, 2021 |
14 | Bills vs Buccaneers | TB 33, BUF 27 (OT) Sunday, December 12th, 2021 |
15 | Panthers vs Bills | BUF 31, CAR 14 Sunday, December 19th, 2021 |
16 | Bills vs Patriots | BUF 33, NE 21 Sunday, December 26th, 2021 |
17 | Bills Bye Week | |
17 | Falcons vs Bills | BUF 29, ATL 15 Sunday, January 2nd, 2022 |
18 | Jets vs Bills | BUF 27, NYJ 10 Sunday, January 9th, 2022 |
Patriots vs Bills AFC Wild Card Playoffs | BUF 47, NE 17 Saturday, January 15th, 2022 | |
Bills vs Chiefs AFC Divisional Playoffs | KC 42, BUF 36 (OT) Sunday, January 23rd, 2022 |
Current NFL Matchup Lines
Game |
![]() Play |
---|---|
Bills
Rams
9/08/22 8:20pm EDT | |
Saints
Falcons
9/11/22 1:00pm EDT | |
Jaguars
commanders
9/11/22 1:00pm EDT | |
Ravens
Jets
9/11/22 1:00pm EDT | |
Patriots
Dolphins
9/11/22 1:00pm EDT | |
Colts
Texans
9/11/22 1:00pm EDT | |
Eagles
Lions
9/11/22 1:00pm EDT | |
Steelers
Bengals
9/11/22 1:00pm EDT | |
49ers
Bears
9/11/22 1:00pm EDT | |
Browns
Panthers
9/11/22 1:00pm EDT |