Indianapolis Colts vs San Francisco 49ers Odds

The Colts will play the 49ers on Sunday, October 24th, 2021. The matchup takes place at Levi's Stadium. Watch this exciting Week 7 matchup at 8:20 pm EDT. Check local listings for coverage on NBC.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Best Colts at 49ers Odds


Best Point Spread Betting Odds
TBDTBD
Point Spread odds are updating, please check back soon.

Best Total Betting Odds
OverUnder
Total odds are updating, please check back soon.

Best Moneyline Betting Odds
TBDTBD
Moneyline odds are updating, please check back soon.

NFL Odds Example

NFL Odds and Outcomes Explained
Game Book

Indianapolis Colts at San Francisco 49ers Prop Bets

NFL Prop Bets
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Bet
Colts
49ers
10/24/21 8:20pm EDT
Pending BetRivers

Recent Meetings Since 2017

Recent Meetings Since 2017
WeekGameResultMargin
2021
Week 7
Colts vs 49ers
Sunday, October 24th, 2021
IND 30, SF 18
Levi's Stadium
Colts by 12
2018
Preseason Week 3
49ers vs Colts
Saturday, August 25th, 2018
IND 23, SF 17
Lucas Oil Stadium
Colts by 6
2017
Week 5
49ers vs Colts
Sunday, October 8th, 2017
IND 26, SF 23 (OT)
Lucas Oil Stadium
Colts by 3

Team Standings

2021-2022 NFL Regular Season Standings - Indianapolis Colts, San Francisco 49ers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xy - San Francisco 49ers10700.5884273654-4-06-3-02-4-00.3337-5-00.5832W4-1-0
Indianapolis Colts9800.5294513654-5-05-3-03-3-00.5007-5-00.5832L3-2-0

Indianapolis Colts & San Francisco 49ers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Indianapolis Colts Futures Odds
2024-25 Indianapolis Colts Super Bowl Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
Colts
+6600
Bet
+6600
Bet
San Francisco 49ers Futures Odds
2024-25 San Francisco 49ers Super Bowl Odds

Team
BetRivers Sports Betting BetRivers BetMGM Sports Betting BetMGM
49ers
+650
Bet
+650
Bet

Indianapolis Colts & San Francisco 49ers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Indianapolis Colts vs San Francisco 49ers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 24th, 2021 at 8:20 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Indianapolis Colts vs San Francisco 49ers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Indianapolis Colts vs San Francisco 49ers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other October 24, 2021 NFL Games

Matchup
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Baltimore Ravens
New York Jets vs
New England Patriots
Atlanta Falcons vs
Miami Dolphins
Kansas City Chiefs vs
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Washington Football Team vs
Green Bay Packers
Carolina Panthers vs
New York Giants
Philadelphia Eagles vs
Las Vegas Raiders
Detroit Lions vs
Los Angeles Rams
Houston Texans vs
Arizona Cardinals
Chicago Bears vs
Tampa Bay Buccaneers
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