Indianapolis Colts vs San Francisco 49ers Odds

The Colts will play the 49ers on Sunday, October 24th, 2021. The matchup takes place at Levi's Stadium - Santa Clara, CA. Watch this exciting Week 7 matchup at 8:20 pm EDT. Check local listings for coverage on NBC.

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Game

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3:04pm EDT
TBD VA
No Point Spread lines available for this game

Recent Meetings Since 2017

WeekGameResultMargin
2021
Week 7
Colts vs 49ers
Sunday, October 24th, 2021
IND 30, SF 18
Levi's Stadium - Santa Clara, CA
Colts by 12
2018
Preseason Week 3
49ers vs Colts
Saturday, August 25th, 2018
Preseason
IND 23, SF 17
Lucas Oil Stadium - Indianapolis, IN
Colts by 6
2017
Week 5
49ers vs Colts
Sunday, October 8th, 2017
IND 26, SF 23 (OT)
Lucas Oil Stadium - Indianapolis, IN
Colts by 3

Regular Season Team Standings

2021 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
Indianapolis Colts
7-5-0 3-3-0 9 8 0 0.529 4-5-0 5-3-0 3-2-0
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San Francisco 49ers
7-5-0 2-4-0 10 7 0 0.588 4-4-0 6-3-0 4-1-0

Team Stats

Indianapolis Colts Team Stats
Stat Indianapolis Colts Opponents
Total 1st Downs 354 334
Total Offensive Yards 5901 5834
Total Rushing Yards 2540 1854
Total Passing Yards 3361 3980
Sacks 33 32
Field Goals 29 / 35 22 / 27
Touchdowns 52 43
Avg Time Of Possession 32:03 28:33
Turnover Ratio +14

San Francisco 49ers Team Stats
Stat San Francisco 49ers Opponents
Total 1st Downs 361 318
Total Offensive Yards 6387 5270
Total Rushing Yards 2166 1760
Total Passing Yards 4221 3510
Sacks 48 33
Field Goals 27 / 32 21 / 27
Touchdowns 50 43
Avg Time Of Possession 31:09 29:47
Turnover Ratio -4

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

Indianapolis Colts Season Win Total
2022 NFL Indianapolis Colts Season Win Total
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Indianapolis Colts
2022 Season Win Total
San Francisco 49ers Season Win Total
2022 NFL San Francisco 49ers Season Win Total
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San Francisco 49ers
2022 Season Win Total

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Indianapolis Colts Futures Odds
2023 Super Bowl Winner Odds

Team
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Indianapolis Colts
San Francisco 49ers Futures Odds
2023 Super Bowl Winner Odds

Team
BetRivers BetRivers
San Francisco 49ers

2021 Indianapolis Colts Games & Results

WeekMatchupDate & Time
Preseason 1Panthers vs
Colts
Preseason
IND 21, CAR 18
Sunday, August 15th, 2021
Preseason 2Colts vs
Vikings
Preseason
IND 12, MIN 10
Saturday, August 21st, 2021
Preseason 3Colts vs
Lions
Preseason
IND 27, DET 17
Friday, August 27th, 2021
Week 1Seahawks vs
Colts
SEA 28, IND 16
Sunday, September 12th, 2021
Week 2Rams vs
Colts
LAR 27, IND 24
Sunday, September 19th, 2021
Week 3Colts vs
Titans
TEN 25, IND 16
Sunday, September 26th, 2021
Week 4Colts vs
Dolphins
IND 27, MIA 17
Sunday, October 3rd, 2021
Week 5Colts vs
Ravens
BAL 31, IND 25 (OT)
Monday, October 11th, 2021
Week 6Texans vs
Colts
IND 31, HOU 3
Sunday, October 17th, 2021
Week 7Colts vs
49ers
IND 30, SF 18
Sunday, October 24th, 2021
Week 8Titans vs
Colts
TEN 34, IND 31 (OT)
Sunday, October 31st, 2021
Week 9Jets vs
Colts
IND 45, NYJ 30
Thursday, November 4th, 2021
Week 10Jaguars vs
Colts
IND 23, JAX 17
Sunday, November 14th, 2021
Week 11Colts vs
Bills
IND 41, BUF 15
Sunday, November 21st, 2021
Week 12Buccaneers vs
Colts
TB 38, IND 31
Sunday, November 28th, 2021
Week 13Colts vs
Texans
IND 31, HOU 0
Sunday, December 5th, 2021
Week 14Colts
Bye Week
Week 15Patriots vs
Colts
IND 27, NE 17
Saturday, December 18th, 2021
Week 16Colts vs
Cardinals
IND 22, ARI 16
Saturday, December 25th, 2021
Week 17Raiders vs
Colts
LV 23, IND 20
Sunday, January 2nd, 2022
Week 18Colts vs
Jaguars
JAX 26, IND 11
Sunday, January 9th, 2022

2021 San Francisco 49ers Games & Results

WeekMatchupDate & Time
Preseason 1Chiefs vs
49ers
Preseason
KC 19, SF 16
Saturday, August 14th, 2021
Preseason 249ers vs
Chargers
Preseason
SF 15, LAC 10
Sunday, August 22nd, 2021
Preseason 3Raiders vs
49ers
Preseason
SF 34, LV 10
Sunday, August 29th, 2021
Week 149ers vs
Lions
SF 41, DET 33
Sunday, September 12th, 2021
Week 249ers vs
Eagles
SF 17, PHI 11
Sunday, September 19th, 2021
Week 3Packers vs
49ers
GB 30, SF 28
Sunday, September 26th, 2021
Week 4Seahawks vs
49ers
SEA 28, SF 21
Sunday, October 3rd, 2021
Week 549ers vs
Cardinals
ARI 17, SF 10
Sunday, October 10th, 2021
Week 649ers
Bye Week
Week 7Colts vs
49ers
IND 30, SF 18
Sunday, October 24th, 2021
Week 849ers vs
Bears
SF 33, CHI 22
Sunday, October 31st, 2021
Week 9Cardinals vs
49ers
ARI 31, SF 17
Sunday, November 7th, 2021
Week 10Rams vs
49ers
SF 31, LAR 10
Monday, November 15th, 2021
Week 1149ers vs
Jaguars
SF 30, JAX 10
Sunday, November 21st, 2021
Week 12Vikings vs
49ers
SF 34, MIN 26
Sunday, November 28th, 2021
Week 1349ers vs
Seahawks
SEA 30, SF 23
Sunday, December 5th, 2021
Week 1449ers vs
Bengals
SF 26, CIN 23 (OT)
Sunday, December 12th, 2021
Week 15Falcons vs
49ers
SF 31, ATL 13
Sunday, December 19th, 2021
Week 1649ers vs
Titans
TEN 20, SF 17
Thursday, December 23rd, 2021
Week 17Texans vs
49ers
SF 23, HOU 7
Sunday, January 2nd, 2022
Week 1849ers vs
Rams
SF 27, LAR 24 (OT)
Sunday, January 9th, 2022
Wild Card49ers vs
Cowboys
NFC Wild Card Playoffs
SF 23, DAL 17
Sunday, January 16th, 2022
Divisional Round49ers vs
Packers
NFC Divisional Playoffs
SF 13, GB 10
Saturday, January 22nd, 2022
Conference Championship49ers vs
Rams
NFC Championship
LAR 20, SF 17
Sunday, January 30th, 2022

Current NFL Matchup Lines

Next 10 NFL Matchups
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Game
BetRivers BetRivers
Bet
Bears
Seahawks
8/18/22 8:00pm EDT
Panthers
Patriots
8/19/22 7:00pm EDT
Saints
Packers
8/19/22 8:00pm EDT
Texans
Rams
8/19/22 10:00pm EDT
Broncos
Bills
8/20/22 1:00pm EDT
Lions
Colts
8/20/22 1:00pm EDT
Commanders
Chiefs
8/20/22 4:00pm EDT
Steelers
Jaguars
8/20/22 7:00pm EDT
Raiders
Dolphins
8/20/22 7:00pm EDT
49ers
Vikings
8/20/22 7:00pm EDT
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