Los Angeles Chargers vs San Francisco 49ers Odds

The Chargers will play the 49ers on Friday, August 25th, 2023. The matchup takes place at Levi's Stadium. Watch this exciting preseason matchup at 10:00 pm EDT. Check local listings for coverage on NFL NET.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

The 2023-24 NFL preseason is underway for the Los Angeles Chargers and San Francisco 49ers. Let's review each team's stats in anticipation of their upcoming matchup. Preseason results do not affect a team's chances of making the playoffs. Remember, the regular season begins soon!

  • SportsBetting3.com Power Rankings - The Los Angeles Chargers currently have a 95.67 preseason power ranking (89.33 for the 2022 preseason). Contrast this to the San Francisco 49ers who'll play this matchup with a 91.33 preseason power ranking (94.00 in 2022).
  • Away Los Angeles Chargers - The Los Angeles Chargers currently have a 1-0-0 record as an away team (0-1-0 in 2022). They now rank 2nd for away team wins in the preseason standings.
  • Home San Francisco 49ers - The San Francisco 49ers currently have a 1-0-0 record as a home team (1-0-0 in 2022). They now rank 2nd for home team wins in the preseason standings.
  • Points Scored - The Los Angeles Chargers rank 5th (51) in the preseason, with the San Francisco 49ers ranked 19th (28) for points scored in the 2023 preseason.
  • Points Against - The Los Angeles Chargers are 11th (39) in the preseason for points against. The San Francisco 49ers stand 3rd (54) in the 2023 preseason for points against.
  • Team Records - The Los Angeles Chargers have a 1-1-0 preseason record, with the San Francisco 49ers at 1-1-0. Last year, the Los Angeles Chargers had a 0-3-0 preseason record, with the San Francisco 49ers finishing with a 2-1-0 standing.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arrr, ye scurvy dogs! The Los Angeles Chargers be travelin' to San Francisco...to face them 49ers at Levi's Stadium on August 25th. Preseason Week 3, mateys! Both teams stand at 1-1-0, but that don't matter much in this exhibition...of footy! Don't ye dare be bettin' yer pieces of eight on this game, unless ye be visitin' SportsBetting3.com to review the odds below. Savvy?

The Chargers be seekin' redemption after their last loss. They'll be fightin' tooth and nail...to get that win against them 49ers. But them 49ers be no pushovers, ye scallywags! They be lookin' to defend their turf at Levi's Stadium, ready to show who's the boss.

So gather yer crew, me hearties, and set sail to Levi's Stadium. Watch these teams battle...like thunder and lightning in the night sky. But remember, don't be a fool and bet on this game without consultin' SportsBetting3.com. Arrr!

Best Chargers at 49ers Odds


Best Point Spread Betting Odds
Underdog

Los Angeles Chargers
Favorite

San Francisco 49ers
The San Francisco 49ers have a -7.5 -110 point spread at BetMGM VA. They are the point spread favorite in this matchup. The Los Angeles Chargers have a +7.5 -110 point spread at BetMGM VA. The Los Angeles Chargers are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 38 points. Risk $110 to win $100. BetMGM has the best under line of 38 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Los Angeles Chargers
Favorite

San Francisco 49ers
The San Francisco 49ers are the -350 moneyline favorite. Risk $350 to win $100 on the San Francisco 49ers at BetMGM. The Los Angeles Chargers are the +280 underdog at BetMGM. Risk $100 to win $280 on the Los Angeles Chargers. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Los Angeles Chargers vs San Francisco 49ers NFL game on Friday, August 25th, 2023?

The San Francisco 49ers are -7.5 -110 point spread favorites at BetMGM, while the Los Angeles Chargers are +7.5 -110 point spread underdogs at BetMGM.

What is the over-under total line for the Los Angeles Chargers vs San Francisco 49ers NFL game on Friday, August 25th, 2023?

The best over line is 38 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 38 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Los Angeles Chargers vs San Francisco 49ers NFL game on Friday, August 25th, 2023?

The San Francisco 49ers are the -350 moneyline favorite at BetMGM and the Los Angeles Chargers are the +280 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Chargers
49ers
8/25/23 10:00pm EDT
+7.5 -110-7.5 -110
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Underdog Los Angeles Chargers - Los Angeles Chargers bettors risk $100 to win $90.91 at -110 odds.

A +7.5 Los Angeles Chargers underdog bet wins if they lose by 7 or fewer, tie, or win outright. Your bet loses if they lose by 8 or more.

Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.

A -7.5 San Francisco 49ers favorite bet wins if they win by 8 or more. Your bet loses if they win by 7 or fewer, tie, or lose outright.

Los Angeles Chargers at San Francisco 49ers Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Chargers
49ers
8/25/23 10:00pm EDT
Pending BetMGM

Recent Meetings Since 2019

Recent Meetings Since 2019
WeekGameResultMargin
2023
Preseason Week 3
Chargers vs 49ers
Friday, August 25th, 2023
LAC 23, SF 12
Levi's Stadium
Chargers by 11
2022
Week 10
Chargers vs 49ers
Sunday, November 13th, 2022
SF 22, LAC 16
Levi's Stadium
49ers by 6
2021
Preseason Week 2
49ers vs Chargers
Sunday, August 22nd, 2021
SF 15, LAC 10
SoFi Stadium
49ers by 5
2019
Preseason Week 4
Chargers vs 49ers
Thursday, August 29th, 2019
LAC 27, SF 24
Levi's Stadium
Chargers by 3

Team Standings

2023-2024 NFL Regular Season Standings - Los Angeles Chargers, San Francisco 49ers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz* - San Francisco 49ers12500.7064912985-3-07-2-05-1-00.83310-2-00.8331L3-2-0
Los Angeles Chargers51200.2943463982-7-03-5-01-5-00.1673-9-00.2505L0-5-0

Los Angeles Chargers & San Francisco 49ers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Los Angeles Chargers Futures Odds
2024-25 Los Angeles Chargers Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Chargers
+6600
Bet
San Francisco 49ers Futures Odds
2024-25 San Francisco 49ers Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
49ers
+750
Bet

Los Angeles Chargers & San Francisco 49ers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Los Angeles Chargers vs San Francisco 49ers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, August 25th, 2023 at 10:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Los Angeles Chargers vs San Francisco 49ers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Los Angeles Chargers vs San Francisco 49ers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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