New England Patriots vs San Francisco 49ers Odds

The Patriots will play the 49ers on Sunday, September 29th, 2024. The matchup takes place at Levi's Stadium. Watch this exciting Week 4 matchup at 4:05 pm EDT. Check local listings for coverage on FOX.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

The New England Patriots and San Francisco 49ers will take the field at Levi's Stadium for a key Week 4 matchup on Sunday, September 29th, 2024. Have a look at each team's key performance stats below as they continue to make their way through the 2024-25 NFL regular season.

  • SportsBetting3.com Power Rankings - Heading into Week 4 of the 2024-25 season, the New England Patriots have a power ranking of 90.33. Our calculations have the San Francisco 49ers at a 93.33 power ranking.
  • Away New England Patriots - Now in the middle of the season, the New England Patriots have a 1-1-0 record as an away team, ranking them 2nd in the league for away team wins.
  • Home San Francisco 49ers - The San Francisco 49ers come to this Week 4 matchup with a 1-0-0 record as a home team. They rank 2nd in the league for home team wins so far this season.
  • Points Scored - The New England Patriots currently rank 24th (39) on the edge of Week 4, with the San Francisco 49ers ranked 6th (73) for points scored to date.
  • Points Against - The New England Patriots stand 15th (57) in the middle weeks of the regular season for points against. As for the San Francisco 49ers, they currently rank 8th (69) for points against.
  • Team Records - Standings become more important now more than ever. Approaching Week 4, the New England Patriots have a 1-2-0 record, with the San Francisco 49ers at 1-2-0 for the 2024-25 regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The New England Patriots be takin' on the San Francisco 49ers!

The Patriots be standin' at 1-2-0, while the 49ers be matchin' their record.

Mid-season games be crucial to shapin' the standings for both teams. Bet this game at BetMGM or our preferred sports betting partner BetRivers.

This important Week 4 clash be happenin' at Levi's Stadium in the heart of San Francisco. Look at this game's prop bets and compare odds from partner sports betting sites.

The Patriots be ranked at 90.33 in the SportsBetting3.com NFL Power Rankings, while the 49ers be sittin' pretty at 93.33. Bet wisely, me hearties!

Best Patriots at 49ers Odds


Best Point Spread Betting Odds
Underdog

New England Patriots
Favorite

San Francisco 49ers
The San Francisco 49ers have a -10.5 -110 point spread at BetMGM VA. They are the point spread favorite in this matchup. The New England Patriots have a +10.5 -110 point spread at BetMGM VA. The New England Patriots are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 41.5 points. Risk $110 to win $100. BetMGM has the best under line of 41.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

New England Patriots
Favorite

San Francisco 49ers
The San Francisco 49ers are the -600 moneyline favorite. Risk $600 to win $100 on the San Francisco 49ers at BetMGM. The New England Patriots are the +450 underdog at BetMGM. Risk $100 to win $450 on the New England Patriots. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the New England Patriots vs San Francisco 49ers NFL game on Sunday, September 29th, 2024?

The San Francisco 49ers are -10.5 -110 point spread favorites at BetMGM, while the New England Patriots are +10.5 -110 point spread underdogs at BetMGM.

What is the over-under total line for the New England Patriots vs San Francisco 49ers NFL game on Sunday, September 29th, 2024?

The best over line is 41.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 41.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the New England Patriots vs San Francisco 49ers NFL game on Sunday, September 29th, 2024?

The San Francisco 49ers are the -600 moneyline favorite at BetMGM and the New England Patriots are the +450 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Patriots
49ers
9/29/24 4:05pm EDT
+10.5 -110-10.5 -110
Bet $100 at BetMGM Virginia
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Gambling Problem? Call 1-888-532-3500

Underdog New England Patriots - New England Patriots bettors risk $100 to win $90.91 at -110 odds.

A +10.5 New England Patriots underdog bet wins if they lose by 10 or fewer, tie, or win outright. Your bet loses if they lose by 11 or more.

Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.

A -10.5 San Francisco 49ers favorite bet wins if they win by 11 or more. Your bet loses if they win by 10 or fewer, tie, or lose outright.

New England Patriots at San Francisco 49ers Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Patriots
49ers
First Team To Score
9/29/24 4:05pm EDT
+175-225Bet
Patriots
49ers
No Touchdown
To Score 1st Touchdown
9/29/24 4:05pm EDT
+210-300+8000Bet
Patriots
49ers
Game to Overtime
9/29/24 4:05pm EDT
Yes +950No -5000Bet
Patriots
49ers
Safety to be Scored
9/29/24 4:05pm EDT
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Brock Purdy
Total Passing Yards
NE at SF
9/29/24 4:05pm EDT
247.5 o -115247.5 u -115Bet
Brock Purdy
Longest Passing Completion
NE at SF
9/29/24 4:05pm EDT
36.5 o -12036.5 u -110Bet
Brock Purdy
Total Pass Completions
NE at SF
9/29/24 4:05pm EDT
21.5 o -10521.5 u -125Bet
Brock Purdy
Total Touchdown Passes
NE at SF
9/29/24 4:05pm EDT
1.5 o -1301.5 u +100Bet
BetMGM Sports Betting BetMGM
Brock Purdy
Interceptions Thrown
NE at SF
9/29/24 4:05pm EDT
0.5 o +1050.5 u -140Bet
Jacoby Brissett
Total Touchdown Passes
NE at SF
9/29/24 4:05pm EDT
0.5 o -1400.5 u +105Bet
Jacoby Brissett
Interceptions Thrown
NE at SF
9/29/24 4:05pm EDT
0.5 o -1150.5 u -115Bet
Jacoby Brissett
Total Passing Yards
NE at SF
9/29/24 4:05pm EDT
170.5 o -115170.5 u -115Bet
BetMGM Sports Betting BetMGM
Jacoby Brissett
Total Pass Completions
NE at SF
9/29/24 4:05pm EDT
17.5 o -11017.5 u -120Bet
Jacoby Brissett
Longest Passing Completion
NE at SF
9/29/24 4:05pm EDT
30.5 o -11030.5 u -120Bet
Jake Moody
Total Kicking Points
NE at SF
9/29/24 4:05pm EDT
7.5 o -1407.5 u +105Bet
Joey Slye
Total Kicking Points
NE at SF
9/29/24 4:05pm EDT
5.5 o -1055.5 u -125Bet

Recent Meetings Since 2020

Recent Meetings Since 2020
WeekGameResultMargin
2024
Week 4
Patriots vs 49ers
Sunday, September 29th, 2024
SF 30, NE 13
Levi's Stadium
49ers by 17
2020
Week 7
49ers vs Patriots
Sunday, October 25th, 2020
SF 33, NE 6
Gillette Stadium
49ers by 27

Team Standings

2024-2025 NFL Regular Season Standings - New England Patriots, San Francisco 49ers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
San Francisco 49ers2300.4001261062-1-00-2-00-2-00.0000-3-00.0001L2-3-0
New England Patriots1400.200621020-2-01-2-00-2-00.0001-2-00.3334L1-4-0

New England Patriots & San Francisco 49ers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

New England Patriots Futures Odds
2024-25 New England Patriots Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Patriots
+50000
Bet
San Francisco 49ers Futures Odds
2024-25 San Francisco 49ers Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
49ers
+750
Bet

New England Patriots & San Francisco 49ers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the New England Patriots vs San Francisco 49ers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 29th, 2024 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the New England Patriots vs San Francisco 49ers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the New England Patriots vs San Francisco 49ers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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