The Saints will play the 49ers on Sunday, November 27th, 2022. The matchup takes place at Levi's Stadium. Watch this exciting Week 12 matchup at 4:25 pm EST. Check local listings for coverage on FOX.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Best Saints at 49ers Odds
| Underdog New Orleans Saints | Favorite San Francisco 49ers |
|---|---|
| Over | Under |
|---|---|
| Underdog New Orleans Saints | Favorite San Francisco 49ers |
|---|---|
Matchup Odds FAQs
The San Francisco 49ers are -8.5 -115 point spread favorites at BetMGM, while the New Orleans Saints are +9 -108 point spread underdogs at BetRivers.
The best over line is 43.5 -109 points at BetRivers, which means you risk $109 to win $100 betting the over. The best under line is 43.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The San Francisco 49ers are the -400 moneyline favorite at BetRivers and the New Orleans Saints are the +335 moneyline underdog at BetRivers.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
Saints
49ers
11/27/22 4:25pm EST | +8.5 -105-8.5 -115 |
Underdog New Orleans Saints - New Orleans Saints bettors risk $100 to win $95.24 at -105 odds.
A +8.5 New Orleans Saints underdog bet wins if they lose by 8 or fewer, tie, or win outright. Your bet loses if they lose by 9 or more.
Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $86.96 at -115 odds.
A -8.5 San Francisco 49ers favorite bet wins if they win by 9 or more. Your bet loses if they win by 8 or fewer, tie, or lose outright.
New Orleans Saints at San Francisco 49ers Prop Bets
| BetMGM Bet |
|
|---|---|
Saints
49ers
11/27/22 4:25pm EST | Pending BetMGM |
Recent Meetings Since 2018
| Week | Game | Result | Margin |
|---|---|---|---|
| 2020 Week 10 | 49ers vs Saints Sunday, November 15th, 2020 | NO 27, SF 13 Caesars Superdome | Saints by 14 |
| 2019 Week 14 | 49ers vs Saints Sunday, December 8th, 2019 | SF 48, NO 46 Caesars Superdome | 49ers by 2 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| xz - San Francisco 49ers | 13 | 4 | 0 | 0.765 | 450 | 277 | 8-1-0 | 5-3-0 | 6-0-0 | 1.000 | 10-2-0 | 0.833 | 10W | 5-0-0 |
| New Orleans Saints | 7 | 10 | 0 | 0.412 | 330 | 345 | 4-5-0 | 3-5-0 | 2-4-0 | 0.333 | 5-7-0 | 0.417 | 1L | 3-2-0 |
New Orleans Saints & San Francisco 49ers Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
New Orleans Saints Futures Odds|
Team | BetMGM |
 BetRivers |
|---|---|---|
| Saints | +6600 Bet | +8000 Bet |
|
Team | BetMGM |
BetRivers |
|---|---|---|
| 49ers | +600 Bet | +550 Bet |
New Orleans Saints & San Francisco 49ers Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the New Orleans Saints vs San Francisco 49ers NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, November 27th, 2022 at 4:25 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the New Orleans Saints vs San Francisco 49ers Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the New Orleans Saints vs San Francisco 49ers Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.