New Orleans Saints vs San Francisco 49ers Odds

The Saints will play the 49ers on Sunday, November 27th, 2022. The matchup takes place at Levi's Stadium. Watch this exciting Week 12 matchup at 4:25 pm EST. Check local listings for coverage on FOX.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Best Saints at 49ers Odds


Best Point Spread Betting Odds
Underdog

New Orleans Saints
Favorite

San Francisco 49ers
The San Francisco 49ers have a -8.5 -115 point spread at BetMGM VA. They are the point spread favorite in this matchup. The New Orleans Saints have a +9 -108 point spread at BetRivers. The New Orleans Saints are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 43.5 points. Risk $109 to win $100. BetMGM has the best under line of 43.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

New Orleans Saints
Favorite

San Francisco 49ers
The San Francisco 49ers are the -400 moneyline favorite. Risk $400 to win $100 on the San Francisco 49ers at BetRivers. The New Orleans Saints are the +335 underdog at BetRivers. Risk $100 to win $335 on the New Orleans Saints. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the New Orleans Saints vs San Francisco 49ers NFL game on Sunday, November 27th, 2022?

The San Francisco 49ers are -8.5 -115 point spread favorites at BetMGM, while the New Orleans Saints are +9 -108 point spread underdogs at BetRivers.

What is the over-under total line for the New Orleans Saints vs San Francisco 49ers NFL game on Sunday, November 27th, 2022?

The best over line is 43.5 -109 points at BetRivers, which means you risk $109 to win $100 betting the over. The best under line is 43.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the New Orleans Saints vs San Francisco 49ers NFL game on Sunday, November 27th, 2022?

The San Francisco 49ers are the -400 moneyline favorite at BetRivers and the New Orleans Saints are the +335 moneyline underdog at BetRivers.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Saints
49ers
11/27/22 4:25pm EST
Bet $100 at BetRivers Virginia
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Underdog New Orleans Saints - New Orleans Saints bettors risk $100 to win $92.59 at -108 odds.

A +9 New Orleans Saints underdog bet wins if they lose by 8 or fewer, tie, or win outright. The bet pushes if they lose by 9. Your bet loses if they lose by 10 or more.

Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $88.5 at -113 odds.

A -9 San Francisco 49ers favorite bet wins if they win by 10 or more. The bet pushes if they win by 9. Your bet loses if they win by 8 or fewer, tie, or lose outright.

New Orleans Saints at San Francisco 49ers Prop Bets

NFL Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
Saints
49ers
First Team To Score
11/27/22 4:25pm EST
Bet
Saints
49ers
Tie
First to 15 Points
11/27/22 4:25pm EST
Bet
Saints
49ers
Tie
First to 20 Points
11/27/22 4:25pm EST
Bet
Jimmy Garoppolo
Total Touchdown Passes
NO at SF
11/27/22 4:25pm EST
Bet

Recent Meetings Since 2018

Recent Meetings Since 2018
WeekGameResultMargin
2020
Week 10
49ers vs Saints
Sunday, November 15th, 2020
NO 27, SF 13
Caesars Superdome
Saints by 14
2019
Week 14
49ers vs Saints
Sunday, December 8th, 2019
SF 48, NO 46
Caesars Superdome
49ers by 2

Team Standings

2022-2023 NFL Regular Season Standings - New Orleans Saints, San Francisco 49ers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz - San Francisco 49ers13400.7654502778-1-05-3-06-0-01.00010-2-00.83310W5-0-0
New Orleans Saints71000.4123303454-5-03-5-02-4-00.3335-7-00.4171L3-2-0

New Orleans Saints & San Francisco 49ers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

New Orleans Saints Futures Odds

No Super Bowl TM New Orleans Saints YR: futures available

San Francisco 49ers Futures Odds
2023-24 San Francisco 49ers Super Bowl Odds

Team
BetRivers Sports Betting BetRivers
49ers

New Orleans Saints & San Francisco 49ers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the New Orleans Saints vs San Francisco 49ers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, November 27th, 2022 at 4:25 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the New Orleans Saints vs San Francisco 49ers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the New Orleans Saints vs San Francisco 49ers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other November 27, 2022 NFL Games

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