The 49ers will play the Browns on Sunday, November 30th, 2025. The matchup takes place at Huntington Bank Field. Watch this exciting Week 13 matchup at 1:00 pm EST. Check local listings for coverage on CBS.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
It's now Week 13, as the 2025-26 NFL regular season is coming to a close. This week's action includes a matchup between the San Francisco 49ers and Cleveland Browns. They'll play on Sunday, November 30th, 2025 at Huntington Bank Field, in a game that may affect this season's playoff picture. We've highlighted each team's key performance stats below. Take note of the following as you handicap this matchup.
- SportsBetting3.com Power Rankings - Now Week 13 of the 2025-26 NFL regular season, the San Francisco 49ers have a 93.67 power ranking based on our formula. Their opponent, the Cleveland Browns, currently possess a 87.33 power ranking.
- Away San Francisco 49ers - With the season coming to a close, the San Francisco 49ers have a 5-2-0 record as an away team, ranking them 2nd in the league for away team wins.
- Home Cleveland Browns - The Cleveland Browns come to this Week 13 game with a 2-3-0 record as a home team. They rank 5th in the league for home team wins as the 2025-26 regular season wraps up.
- Points Scored - The San Francisco 49ers currently rank 9th (281) headed into Week 13, with the Cleveland Browns ranked 27th (186) for points scored to date.
- Points Against - As the regular season winds down, the San Francisco 49ers rank 14th (261) for points score against them. Note that the Cleveland Browns now rank 19th (244) for points scored against.
- Team Records - The final games of the season will determine who heads to the playoffs. Heading into Week 13, the San Francisco 49ers have a 8-4-0 record, with the Cleveland Browns at 3-8-0 for the 2025-26 NFL regular season.
Captain Shady Lines
A broken compass is right at least twice a day.

Arr, me hearties! The 49ers face the Browns in a crucial Week 13 showdown.
The regular season be near end, and this game could change playoff fate.
49ers stand at 8-4-0, while Browns lag behind at 3-8-0.
This battle be happenin' at Huntington Bank Field, where tempers will surely flare.
San Francisco be rankin' at 93.67, while Cleveland be at 87.33.
Place a bet at BetRivers or BetMGM, and check out them prop bets below!
We've compared odds from our partner sportsbooks, so set sail for victory!
Best 49ers at Browns Odds
| Underdog Cleveland Browns | Favorite San Francisco 49ers |
|---|---|
| Over | Under |
|---|---|
| Underdog Cleveland Browns | Favorite San Francisco 49ers |
|---|---|
Matchup Odds FAQs
The San Francisco 49ers are -5 -110 point spread favorites at BetMGM, while the Cleveland Browns are +5 -110 point spread underdogs at BetMGM.
The best over line is 35 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 35 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The San Francisco 49ers are the -235 moneyline favorite at BetMGM and the Cleveland Browns are the +195 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
Bet |
|---|---|
49ers
Browns
11/30/25 1:00pm EST | -5 -110+5 -110 |
Underdog Cleveland Browns - Cleveland Browns bettors risk $100 to win $90.91 at -110 odds.
A +5 Cleveland Browns underdog bet wins if they lose by 4 or fewer, tie, or win outright. The bet pushes if they lose by 5. Your bet loses if they lose by 6 or more.
Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.
A -5 San Francisco 49ers favorite bet wins if they win by 6 or more. The bet pushes if they win by 5. Your bet loses if they win by 4 or fewer, tie, or lose outright.
San Francisco 49ers at Cleveland Browns Prop Bets
Bet |
|
|---|---|
49ers
Browns
First Team To Score
11/30/25 1:00pm EST | -145+110Bet |
49ers
Browns
No Touchdown
To Score 1st Touchdown
11/30/25 1:00pm EST | -155+125+3500Bet |
49ers
Browns
Game to Overtime
11/30/25 1:00pm EST | Yes +800No -3000Bet |
49ers
Browns
Safety to be Scored
11/30/25 1:00pm EST | Yes +1000No -3000Bet |
Brock Purdy
Interceptions Thrown
SF at CLE 11/30/25 1:00pm EST | 0.5 o -1350.5 u +105Bet |
Shedeur Sanders
Interceptions Thrown
SF at CLE 11/30/25 1:00pm EST | 0.5 o -2100.5 u +160Bet |
Brock Purdy
Longest Passing Completion
SF at CLE 11/30/25 1:00pm EST | 32.5 o -11032.5 u -118Bet |
Shedeur Sanders
Longest Passing Completion
SF at CLE 11/30/25 1:00pm EST | 31.5 o -11031.5 u -118Bet |
Andre Szmyt
Total Kicking Points
SF at CLE 11/30/25 1:00pm EST | 5.5 o +1055.5 u -140Bet |
Matt Gay
Total Kicking Points
SF at CLE 11/30/25 1:00pm EST | 6.5 o -1306.5 u -105Bet |
Brock Purdy
Total Pass Completions
SF at CLE 11/30/25 1:00pm EST | 18.5 o -11518.5 u -115Bet |
Shedeur Sanders
Total Pass Completions
SF at CLE 11/30/25 1:00pm EST | 13.5 o -14013.5 u +105Bet |
Brock Purdy
Total Passing Yards
SF at CLE 11/30/25 1:00pm EST | 198.5 o -115198.5 u -115Bet |
Shedeur Sanders
Total Passing Yards
SF at CLE 11/30/25 1:00pm EST | 150.5 o -118150.5 u -115Bet |
Brock Purdy
Total Touchdown Passes
SF at CLE 11/30/25 1:00pm EST | 1.5 o +1451.5 u -190Bet |
Shedeur Sanders
Total Touchdown Passes
SF at CLE 11/30/25 1:00pm EST | 0.5 o -1450.5 u +105Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 13 | 49ers vs Browns Sunday, November 30th, 2025 | SF 26, CLE 8 Huntington Bank Field | 49ers by 18 |
| 2023 Week 6 | 49ers vs Browns Sunday, October 15th, 2023 | CLE 19, SF 17 Cleveland Browns Stadium | Browns by 2 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| San Francisco 49ers | 9 | 4 | 0 | 0.692 | 307 | 269 | 3-2-0 | 6-2-0 | 4-1-0 | 0.800 | 8-2-0 | 0.800 | 3W | 4-1-0 |
| Cleveland Browns | 3 | 10 | 0 | 0.231 | 223 | 301 | 2-5-0 | 1-5-0 | 0-4-0 | 0.000 | 2-7-0 | 0.222 | 2L | 1-4-0 |
San Francisco 49ers & Cleveland Browns Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
San Francisco 49ers Futures Odds|
Team | |
|---|---|
| 49ers | +2200 Bet |
No Super Bowl TM Cleveland Browns YR: futures available
San Francisco 49ers & Cleveland Browns Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco 49ers vs Cleveland Browns NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, November 30th, 2025 at 1:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Cleveland Browns Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Cleveland Browns Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other November 30, 2025 NFL Games
- Los Angeles Rams vs Carolina Panthers - 11/30/25 1:00pm EST
- Jacksonville Jaguars vs Tennessee Titans - 11/30/25 1:00pm EST
- Arizona Cardinals vs Tampa Bay Buccaneers - 11/30/25 1:00pm EST
- Atlanta Falcons vs New York Jets - 11/30/25 1:00pm EST
- Houston Texans vs Indianapolis Colts - 11/30/25 1:00pm EST
- New Orleans Saints vs Miami Dolphins - 11/30/25 1:03pm EST
- Minnesota Vikings vs Seattle Seahawks - 11/30/25 4:05pm EST
- Las Vegas Raiders vs Los Angeles Chargers - 11/30/25 4:25pm EST
- Buffalo Bills vs Pittsburgh Steelers - 11/30/25 4:25pm EST
- Denver Broncos vs Washington Commanders - 11/30/25 8:20pm EST