San Francisco 49ers vs Los Angeles Chargers Odds

The 49ers will play the Chargers on Sunday, August 22nd, 2021. The matchup takes place at SoFi Stadium. Watch this exciting preseason matchup at 7:30 pm EDT. Check local listings for coverage on NFL NET.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Best 49ers at Chargers Odds


Best Point Spread Betting Odds
Underdog

Favorite

Point Spread odds are updating, please check back soon.

Best Total Betting Odds
OverUnder
Total odds are updating, please check back soon.

Best Moneyline Betting Odds
Underdog

Favorite

Moneyline odds are updating, please check back soon.

NFL Odds Example

NFL Odds and Outcomes Explained

Game

Bet
7:29pm EST
TBD VA
VA Odds Pending
No VA Point Spread lines available for this game.

San Francisco 49ers at Los Angeles Chargers Prop Bets

NFL Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
49ers
Chargers
8/22/21 7:30pm EDT
Pending BetRivers

Recent Meetings Since 2017

Recent Meetings Since 2017
WeekGameResultMargin
2023
Pre Preseason Week 3
Chargers vs 49ers
Friday, August 25th, 2023
LAC 23, SF 12
Levi's Stadium
Chargers by 11
2022
Week 10
Chargers vs 49ers
Sunday, November 13th, 2022
SF 22, LAC 16
Levi's Stadium
49ers by 6
2021
Pre Preseason Week 2
49ers vs Chargers
Sunday, August 22nd, 2021
SF 15, LAC 10
SoFi Stadium
49ers by 5
2019
Pre Preseason Week 4
Chargers vs 49ers
Thursday, August 29th, 2019
LAC 27, SF 24
Levi's Stadium
Chargers by 3
2018
Week 4
49ers vs Chargers
Sunday, September 30th, 2018
LAC 29, SF 27
Dignity Health Sports Park
Chargers by 2
2018
Pre Preseason Week 4
Chargers vs 49ers
Thursday, August 30th, 2018
LAC 23, SF 21
Levi's Stadium
Chargers by 2
2017
Pre Preseason Week 4
Chargers vs 49ers
Thursday, August 31st, 2017
SF 23, LAC 13
Levi's Stadium
49ers by 10

Team Standings

2021-2022 NFL Regular Season Standings - San Francisco 49ers, Los Angeles Chargers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xy - San Francisco 49ers10700.5884273654-4-06-3-02-4-00.3337-5-00.5832W4-1-0
Los Angeles Chargers9800.5294744595-4-04-4-03-3-00.5006-6-00.5001L2-3-0

San Francisco 49ers & Los Angeles Chargers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

San Francisco 49ers Futures Odds
2023-24 San Francisco 49ers Super Bowl Odds

Team
BetRivers Sports Betting BetRivers
49ers
Los Angeles Chargers Futures Odds

No Super Bowl TM Los Angeles Chargers YR: futures available

San Francisco 49ers & Los Angeles Chargers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco 49ers vs Los Angeles Chargers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, August 22nd, 2021 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Los Angeles Chargers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Los Angeles Chargers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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