San Francisco 49ers vs Los Angeles Chargers Odds

The 49ers will play the Chargers on Sunday, August 22nd, 2021. The matchup takes place at SoFi Stadium. Watch this exciting preseason matchup at 7:30 pm EDT. Check local listings for coverage on NFL NET.

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6:52pm EST
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San Francisco 49ers at Los Angeles Chargers Prop Bets

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49ers
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8/22/21 7:30pm EDT
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Recent Meetings Since 2017

WeekGameResultMargin
2022
Week 10
Chargers vs 49ers
Sunday, November 13th, 2022
SF 22, LAC 16
Levi's Stadium
49ers by 6
2021
Preseason Week 2
49ers vs Chargers
Sunday, August 22nd, 2021
SF 15, LAC 10
SoFi Stadium
49ers by 5
2019
Preseason Week 4
Chargers vs 49ers
Thursday, August 29th, 2019
LAC 27, SF 24
Levi's Stadium
Chargers by 3
2018
Week 4
49ers vs Chargers
Sunday, September 30th, 2018
LAC 29, SF 27
Dignity Health Sports Park
Chargers by 2
2018
Preseason Week 4
Chargers vs 49ers
Thursday, August 30th, 2018
LAC 23, SF 21
Levi's Stadium
Chargers by 2
2017
Preseason Week 4
Chargers vs 49ers
Thursday, August 31st, 2017
SF 23, LAC 13
Levi's Stadium
49ers by 10

Preseason Team Standings

2021 Preseason Standings
Team Conf Div W L T Pct Home Road Last 5
San Francisco 49ers
0-0-0 0-0-0 2 1 0 0.667 1-1-0 1-0-0 2-1-0
Los Angeles Chargers
0-0-0 0-0-0 1 2 0 0.333 0-1-0 1-1-0 1-2-0

Team Stats

San Francisco 49ers Team Stats
Stat San Francisco 49ers Opponents
Total 1st Downs 361 318
Total Offensive Yards 6337 5270
Total Rushing Yards 2161 1760
Total Passing Yards 4437 3510
Sacks 33 48
Field Goals 27 / 32 21 / 27
Touchdowns 50 43
Turnover Ratio -4

Los Angeles Chargers Team Stats
Stat Los Angeles Chargers Opponents
Total 1st Downs 401 383
Total Offensive Yards 6634 6122
Total Rushing Yards 1834 2361
Total Passing Yards 5014 3761
Sacks 31 35
Field Goals 24 / 27 32 / 35
Touchdowns 57 52
Turnover Ratio 0

Team Season Win Totals

The following are each team's season win totals. Learn more about season win totals.

San Francisco 49ers Season Win Total
2022 NFL San Francisco 49ers Season Win Total
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2022 Season Win Total
Los Angeles Chargers Season Win Total
2022 NFL Los Angeles Chargers Season Win Total
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2022 Season Win Total

Team Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

San Francisco 49ers Futures Odds
2023 San Francisco 49ers Super Bowl Winner Odds

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Los Angeles Chargers Futures Odds

No Super Bowl Winner TM Los Angeles Chargers YR: futures available

2021 San Francisco 49ers Games & Results

WeekMatchupDate & Time
Preseason 1Chiefs vs
49ers
KC 19, SF 16
Saturday, August 14th, 2021
Preseason 249ers vs
Chargers
SF 15, LAC 10
Sunday, August 22nd, 2021
Preseason 3Raiders vs
49ers
SF 34, LV 10
Sunday, August 29th, 2021
Week 149ers vs
Lions
SF 41, DET 33
Sunday, September 12th, 2021
Week 249ers vs
Eagles
SF 17, PHI 11
Sunday, September 19th, 2021
Week 3Packers vs
49ers
GB 30, SF 28
Sunday, September 26th, 2021
Week 4Seahawks vs
49ers
SEA 28, SF 21
Sunday, October 3rd, 2021
Week 549ers vs
Cardinals
ARI 17, SF 10
Sunday, October 10th, 2021
Week 649ers
Bye Week
Week 7Colts vs
49ers
IND 30, SF 18
Sunday, October 24th, 2021
Week 849ers vs
Bears
SF 33, CHI 22
Sunday, October 31st, 2021
Week 9Cardinals vs
49ers
ARI 31, SF 17
Sunday, November 7th, 2021
Week 10Rams vs
49ers
SF 31, LAR 10
Monday, November 15th, 2021
Week 1149ers vs
Jaguars
SF 30, JAX 10
Sunday, November 21st, 2021
Week 12Vikings vs
49ers
SF 34, MIN 26
Sunday, November 28th, 2021
Week 1349ers vs
Seahawks
SEA 30, SF 23
Sunday, December 5th, 2021
Week 1449ers vs
Bengals
SF 26, CIN 23 (OT)
Sunday, December 12th, 2021
Week 15Falcons vs
49ers
SF 31, ATL 13
Sunday, December 19th, 2021
Week 1649ers vs
Titans
TEN 20, SF 17
Thursday, December 23rd, 2021
Week 17Texans vs
49ers
SF 23, HOU 7
Sunday, January 2nd, 2022
Week 1849ers vs
Rams
SF 27, LAR 24 (OT)
Sunday, January 9th, 2022
Wild Card49ers vs
Cowboys
NFC Wild Card Playoffs
SF 23, DAL 17
Sunday, January 16th, 2022
Divisional Round49ers vs
Packers
NFC Divisional Playoffs
SF 13, GB 10
Saturday, January 22nd, 2022
Conference Championship49ers vs
Rams
NFC Championship
LAR 20, SF 17
Sunday, January 30th, 2022

2021 Los Angeles Chargers Games & Results

WeekMatchupDate & Time
Preseason 1Chargers vs
Rams
LAC 13, LAR 6
Saturday, August 14th, 2021
Preseason 249ers vs
Chargers
SF 15, LAC 10
Sunday, August 22nd, 2021
Preseason 3Chargers vs
Seahawks
SEA 27, LAC 0
Saturday, August 28th, 2021
Week 1Chargers vs
TBD
LAC 20, WSH 16
Sunday, September 12th, 2021
Week 2Cowboys vs
Chargers
DAL 20, LAC 17
Sunday, September 19th, 2021
Week 3Chargers vs
Chiefs
LAC 30, KC 24
Sunday, September 26th, 2021
Week 4Raiders vs
Chargers
LAC 28, LV 14
Monday, October 4th, 2021
Week 5Browns vs
Chargers
LAC 47, CLE 42
Sunday, October 10th, 2021
Week 6Chargers vs
Ravens
BAL 34, LAC 6
Sunday, October 17th, 2021
Week 7Chargers
Bye Week
Week 8Patriots vs
Chargers
NE 27, LAC 24
Sunday, October 31st, 2021
Week 9Chargers vs
Eagles
LAC 27, PHI 24
Sunday, November 7th, 2021
Week 10Vikings vs
Chargers
MIN 27, LAC 20
Sunday, November 14th, 2021
Week 11Steelers vs
Chargers
LAC 41, PIT 37
Sunday, November 21st, 2021
Week 12Chargers vs
Broncos
DEN 28, LAC 13
Sunday, November 28th, 2021
Week 13Chargers vs
Bengals
LAC 41, CIN 22
Sunday, December 5th, 2021
Week 14Giants vs
Chargers
LAC 37, NYG 21
Sunday, December 12th, 2021
Week 15Chiefs vs
Chargers
KC 34, LAC 28 (OT)
Thursday, December 16th, 2021
Week 16Chargers vs
Texans
HOU 41, LAC 29
Sunday, December 26th, 2021
Week 17Broncos vs
Chargers
LAC 34, DEN 13
Sunday, January 2nd, 2022
Week 18Chargers vs
Raiders
LV 35, LAC 32 (OT)
Sunday, January 9th, 2022

Other August 22, 2021 NFL Games

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