The 49ers will play the Chargers on Thursday, August 20th, 2026. The matchup takes place at SoFi Stadium. Watch this exciting preseason matchup at 10:00 pm EDT. Check local listings for coverage on NFL Net.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2026-27 NFL preseason is underway for the San Francisco 49ers and Los Angeles Chargers. Let's review each team's stats in anticipation of their upcoming matchup. Preseason results do not affect a team's chances of making the playoffs. Remember, the regular season begins soon!
- SportsBetting3.com Power Rankings - The San Francisco 49ers currently have a 93.33 preseason power ranking (92.33 for the 2025 preseason). Contrast this to the Los Angeles Chargers who'll play this matchup with a 99.67 preseason power ranking (96.33 in 2025).
- Away San Francisco 49ers - The San Francisco 49ers currently have a 0-0-0 record as an away team (1-0-0 in 2025). They now rank 2nd for away team wins in the preseason standings.
- Home Los Angeles Chargers - The Los Angeles Chargers currently have a 0-0-0 record as a home team (1-0-0 in 2025). They now rank 2nd for home team wins in the preseason standings.
- Points Scored - The San Francisco 49ers rank 13th (13) in the preseason, with the Los Angeles Chargers ranked 6th (27) for points scored in the 2026 preseason.
- Points Against - The San Francisco 49ers are 8th (19) in the preseason for points against. The Los Angeles Chargers stand 16th (7) in the 2026 preseason for points against.
- Team Records - The San Francisco 49ers have a 0-1-0 preseason record, with the Los Angeles Chargers at 1-0-0. Last year, the San Francisco 49ers had a 2-1-0 preseason record, with the Los Angeles Chargers finishing with a 2-2-0 standing.
Best 49ers at Chargers Odds
| Underdog San Francisco 49ers | Favorite Los Angeles Chargers |
|---|---|
| Over | Under |
|---|---|
| Underdog San Francisco 49ers | Favorite Los Angeles Chargers |
|---|---|
Matchup Odds FAQs
The Los Angeles Chargers are -1 -108 point spread favorites at BetRivers, while the San Francisco 49ers are +1 -113 point spread underdogs at BetRivers.
The best over line is 38.5 -113 points at BetRivers, which means you risk $113 to win $100 betting the over. The best under line is 38.5 -108 points at BetRivers, and that means you risk $108 to win $100 betting the under.
The Los Angeles Chargers are the -115 moneyline favorite at BetRivers and the San Francisco 49ers are the -106 moneyline underdog at BetRivers.
NFL Odds Example
|
Game |
 BetRiversBet |
|---|---|
49ers
Chargers
8/20/26 10:00pm EDT | +1 -113-1 -108 |
Underdog San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $88.5 at -113 odds.
A +1 San Francisco 49ers underdog bet wins if the result is a tie, or they win outright. The bet pushes if they lose by 1. Your bet loses if they lose by 2 or more.
Favorite Los Angeles Chargers - Los Angeles Chargers bettors risk $100 to win $92.59 at -108 odds.
A -1 Los Angeles Chargers favorite bet wins if they win by 2 or more. The bet pushes if they win by 1. Your bet loses if the result is a tie, or they lose outright.
San Francisco 49ers at Los Angeles Chargers Prop Bets
| BetRivers Bet |
|
|---|---|
49ers
Chargers
8/20/26 10:00pm EDT | Pending BetRivers |
Recent Meetings Since 2022
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Preseason Week 3 | Chargers vs 49ers Saturday, August 23rd, 2025 | SF 30, LAC 23 Levi's Stadium | 49ers by 7 |
| 2023 Preseason Week 3 | Chargers vs 49ers Friday, August 25th, 2023 | LAC 23, SF 12 Levi's Stadium | Chargers by 11 |
| 2022 Week 10 | Chargers vs 49ers Sunday, November 13th, 2022 | SF 22, LAC 16 Levi's Stadium | 49ers by 6 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Los Angeles Chargers | 0 | 0 | 0 | 0.000 | 0 | 0 | 0-0-0 | 0-0-0 | 0-0-0 | 0.000 | 0-0-0 | 0.000 | 0 | - - |
| San Francisco 49ers | 0 | 0 | 0 | 0.000 | 0 | 0 | 0-0-0 | 0-0-0 | 0-0-0 | 0.000 | 0-0-0 | 0.000 | 0 | - - |
San Francisco 49ers & Los Angeles Chargers Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
San Francisco 49ers Futures Odds|
Team | BetRivers |
|---|---|
| 49ers | +1800 Bet |
|
Team | BetRivers |
|---|---|
| Chargers | +1700 Bet |
San Francisco 49ers & Los Angeles Chargers Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco 49ers vs Los Angeles Chargers NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, August 20th, 2026 at 10:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Los Angeles Chargers Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Los Angeles Chargers Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other August 20, 2026 NFL Games
- Las Vegas Raiders vs Houston Texans - 8/20/26 8:00pm EDT