San Francisco 49ers vs Los Angeles Rams NFL Betting Lines

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The 49ers will play the Rams on Sunday, January 9th, 2022. The matchup takes place at SoFi Stadium. Watch this exciting week 18 matchup at 4:25 pm on FOX.

Best Underdog and Favorite Spread Bets
Underdog

San Francisco 49ers
Favorite

Los Angeles Rams
+4.5 -110 Sb3gen3 -4 -120 Sb3gen1
+4 +100 Sb3gen1 -4 -120 Sb3gen2
+4 +100 Sb3gen2 -4.5 -110 Sb3gen3
SportsBetting3.com has analyzed the latest lines. Review our "Best Spread Bets" table above to smash the books this Sunday. Sb3gen1 has the best favorite Los Angeles Rams spread at -4 points. Sb3gen3 has the best underdog San Francisco 49ers spread at +4.5 points.

Review our point spread betting tutorial and video for more information.
Best Over and Under Total Lines
OverUnder
44.5o -110 Sb3gen2 44.5u -105 Sb3gen1
44.5o -110 Sb3gen3 44.5u -110 Sb3gen2
44.5o -115 Sb3gen1 44.5u -110 Sb3gen3
The over under line estimates the combined total of each team's final score. Sb3gen2 has the best over line of 44.5 points laying $110 to win $100. Sb3gen1 has the best under line of 44.5 u -105.
Best Money Line Bets
Underdog

San Francisco 49ers
Favorite

Los Angeles Rams
+185 Sb3gen1 -215 Sb3gen1
+185 Sb3gen3 -220 Sb3gen2
+180 Sb3gen2 -225 Sb3gen3
Here are money lines for the outright winner. Favorite Los Angeles Rams has a minus value. Lay $215 at Sb3gen1 to win $100. Underdog San Francisco 49ers has a positive value. Risk $100 at Sb3gen1 to win $185.

San Francisco 49ers vs Los Angeles Rams Prop Bets

The following prop bets are available for this matchup.

Super Bowl Odds

Latest Super Bowl odds, if available, for each team. Review odds for other teams and learn the best NFL bets here.

San Francisco 49ers Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
San Francisco 49ers

Cached 2022-01-23 23:16:53
Los Angeles Rams Super Bowl Odds
Super Bowl 2022 Futures Odds
OutcomeSB3Gen SB3Gen
Los Angeles Rams

Cached 2022-01-23 23:16:53

Team Stats

2021 San Francisco 49ers Team Stats
Stat San Francisco 49ers Opponents
Total 1st Downs 361 318
Total Offensive Yards 6387 5270
Total Rushing Yards 2166 1760
Total Passing Yards 4221 3510
Sacks 48 33
Field Goals 27 / 32 21 / 27
Touchdowns 50 43
Avg Time Of Possession 31:09 29:47
Turnover Ratio -4

2021 Los Angeles Rams Team Stats
Stat Los Angeles Rams Opponents
Total 1st Downs 355 347
Total Offensive Yards 6325 5863
Total Rushing Yards 1683 1754
Total Passing Yards 4642 4109
Sacks 50 31
Field Goals 32 / 34 30 / 34
Touchdowns 52 40
Avg Time Of Possession 29:03 31:25
Turnover Ratio +2


Team Standings

2021 Regular Season Standings
Team Conf Div W L T Pct Home Road Last 5
xy
San Francisco 49ers
7-5-0 2-4-0 10 7 0 0.588 4-4-0 6-3-0 4-1-0
xz
Los Angeles Rams
8-4-0 3-3-0 12 5 0 0.706 5-3-0 7-2-0 4-1-0

2021 San Francisco 49ers Games & Results

Bye Week: 6
WeekMatchupDate & Time
1 49ers vs
Lions
SF 41, DET 33
09/12/2021
2 49ers vs
Eagles
SF 17, PHI 11
09/19/2021
3 Packers vs
49ers
GB 30, SF 28
09/26/2021
4 Seahawks vs
49ers
SEA 28, SF 21
10/03/2021
5 49ers vs
Cardinals
ARI 17, SF 10
10/10/2021
6San Francisco 49ers ByeN/A
7 Colts vs
49ers
IND 30, SF 18
10/24/2021
8 49ers vs
Bears
SF 33, CHI 22
10/31/2021
9 Cardinals vs
49ers
ARI 31, SF 17
11/07/2021
10 Rams vs
49ers
SF 31, LAR 10
11/15/2021
11 49ers vs
Jaguars
SF 30, JAX 10
11/21/2021
12 Vikings vs
49ers
SF 34, MIN 26
11/28/2021
13 49ers vs
Seahawks
SEA 30, SF 23
12/05/2021
14 49ers vs
Bengals
SF 26, CIN 23 (OT)
12/12/2021
15 Falcons vs
49ers
SF 31, ATL 13
12/19/2021
16 49ers vs
Titans
TEN 20, SF 17
12/23/2021
17 Texans vs
49ers
SF 23, HOU 7
01/02/2022

2021 Los Angeles Rams Games & Results

Bye Week: 11
WeekMatchupDate & Time
1 Bears vs
Rams
LAR 34, CHI 14
09/12/2021
2 Rams vs
Colts
LAR 27, IND 24
09/19/2021
3 Buccaneers vs
Rams
LAR 34, TB 24
09/26/2021
4 Cardinals vs
Rams
ARI 37, LAR 20
10/03/2021
5 Rams vs
Seahawks
LAR 26, SEA 17
10/07/2021
6 Rams vs
Giants
LAR 38, NYG 11
10/17/2021
7 Lions vs
Rams
LAR 28, DET 19
10/24/2021
8 Rams vs
Texans
LAR 38, HOU 22
10/31/2021
9 Titans vs
Rams
TEN 28, LAR 16
11/07/2021
10 Rams vs
49ers
SF 31, LAR 10
11/15/2021
11Los Angeles Rams ByeN/A
12 Rams vs
Packers
GB 36, LAR 28
11/28/2021
13 Jaguars vs
Rams
LAR 37, JAX 7
12/05/2021
14 Rams vs
Cardinals
LAR 30, ARI 23
12/13/2021
15 Seahawks vs
Rams
LAR 20, SEA 10
12/21/2021
16 Rams vs
Vikings
LAR 30, MIN 23
12/26/2021
17 Rams vs
Ravens
LAR 20, BAL 19
01/02/2022

Other 2022 Week 18 Matchups

MatchupDate & Time
Chiefs vs
Broncos
KC 28, DEN 24
01/08/2022
Cowboys vs
Eagles
DAL 51, PHI 26
01/08/2022
Bengals vs
Browns
CLE 21, CIN 16
01/09/2022
Packers vs
Lions
DET 37, GB 30
01/09/2022
Bears vs
Vikings
MIN 31, CHI 17
01/09/2022
TBD vs
Giants
WSH 22, NYG 7
01/09/2022
Colts vs
Jaguars
JAX 26, IND 11
01/09/2022
Steelers vs
Ravens
PIT 16, BAL 13 (OT)
01/09/2022
Titans vs
Texans
TEN 28, HOU 25
01/09/2022
Saints vs
Falcons
NO 30, ATL 20
01/09/2022
Jets vs
Bills
BUF 27, NYJ 10
01/09/2022
49ers vs
Rams
SF 27, LAR 24 (OT)
01/09/2022
Patriots vs
Dolphins
MIA 33, NE 24
01/09/2022
Seahawks vs
Cardinals
SEA 38, ARI 30
01/09/2022
Panthers vs
Buccaneers
TB 41, CAR 17
01/09/2022
Chargers vs
Raiders
LV 35, LAC 32 (OT)
01/09/2022