The 49ers will play the Titans on Thursday, December 23rd, 2021. The matchup takes place at Nissan Stadium. Watch this exciting Week 16 matchup at 8:20 pm EST. Check local listings for coverage on NFL NET.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Best 49ers at Titans Odds
| Underdog | Favorite |
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| Over | Under |
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| Underdog | Favorite |
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NFL Odds Example
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Game |
Bet |
|---|---|
11:37pm EDT | TBD OH,US |
No OH,US Point Spread lines available for this game.
San Francisco 49ers at Tennessee Titans Prop Bets
 BetMGMBet |
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|---|---|
49ers
Titans
12/23/21 8:20pm EST | Pending BetMGM |
Recent Meetings Since 2017
| Week | Game | Result | Margin |
|---|---|---|---|
| 2021 Week 16 | 49ers vs Titans Thursday, December 23rd, 2021 | TEN 20, SF 17 Nissan Stadium | Titans by 3 |
| 2017 Week 15 | Titans vs 49ers Sunday, December 17th, 2017 | SF 25, TEN 23 Levi's Stadium | 49ers by 2 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| xz* - Tennessee Titans | 12 | 5 | 0 | 0.706 | 419 | 354 | 7-2-0 | 5-3-0 | 5-1-0 | 0.833 | 8-4-0 | 0.667 | 3W | 4-1-0 |
| xy - San Francisco 49ers | 10 | 7 | 0 | 0.588 | 427 | 365 | 4-4-0 | 6-3-0 | 2-4-0 | 0.333 | 7-5-0 | 0.583 | 2W | 4-1-0 |
San Francisco 49ers & Tennessee Titans Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
San Francisco 49ers Futures Odds|
Team | BetMGM |
 BetRivers |
|---|---|---|
| 49ers | +600 Bet | +550 Bet |
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Team | BetMGM |
BetRivers |
|---|---|---|
| Titans | +15000 Bet | +15000 Bet |
San Francisco 49ers & Tennessee Titans Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco 49ers vs Tennessee Titans NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, December 23rd, 2021 at 8:20 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Tennessee Titans Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Tennessee Titans Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other December 23, 2021 NFL Games
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