St. Louis Blues vs Buffalo Sabres Odds

The Blues will play the Sabres on Thursday, November 6th, 2025. Your timezone's face off time is 7:08 pm EST. Check local listings or your nearest streaming app for coverage.

Learn more about NHL Betting with our handy tutorial and guide. We explain money line, total and puck line bets. Plus, a great discussion about exotic bets like NHL parlays and props.


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Table of Contents

Key Matchup Stats

The 2025-26 NHL regular season is off the ground for the St. Louis Blues and Buffalo Sabres. Let's review some key performance data in time for the puck drop at center circle. Though it's still early, keep tabs on the following stats as the season progresses.

  • SportsBetting3.com Power Rankings - The St. Louis Blues have started the 2025-26 regular season with a 88.00 power ranking. The Buffalo Sabres currently posses a 92.67 power ranking as the season gets underway.
  • Away St. Louis Blues - The St. Louis Blues have a 2-4-0 record as an away team, ranking them 5th in the league so far for away team wins. The St. Louis Blues currently rank 3rd for away team losses.
  • Home Buffalo Sabres - The Buffalo Sabres have begun 2025-26 regular season with a 5-2-2 record as a home team. That standing puts them 3rd in the league for home team wins, while they also sit 4th for home team losses.
  • Goals Scored - At this early stage in the regular season, the St. Louis Blues rank 14th (38), with the Buffalo Sabres ranking 14th (38) in the league for goals scored.
  • Goals Against - As for goals scored against each team, the St. Louis Blues stand 1st (59), while the Buffalo Sabres rank 11th (40) so far in the NHL 2025-26 regular season.
  • Team Records - The St. Louis Blues have a 4-8-2 record, with the Buffalo Sabres owning a 5-4-4 record in the first weeks of the regular season.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hear ye, hear ye! The St. Louis Blues are on the road...ready to face the Buffalo Sabres in a battle of hockey magic...on November 6th, 2025. The 2025-26 NHL season is now underway...

With a 4-8-2 record, the Blues are looking to turn things around...while the Sabres, standing at 5-4-4, aim to defend home ice...Both teams have scored 38 goals so far this season...Who will reign supreme in this mystical clash of stick and puck?

Before the puck drops, take a moment to review the odds...Check out our hockey betting sportsbooks for insider tips and tricks...Don't forget to look at the prop bets available below...And for those new to hockey betting, learn how at SportsBetting3.com...

Will the Blues cast a spell to secure a victory...or will the Sabres defend their territory with fiery determination? Only time will tell in this magical showdown of ice warriors...So grab your wands (and maybe a hockey stick) and tune in for the enchanted action on the ice!

Best Blues at Sabres Odds


Best Moneyline Betting Odds
Underdog

St. Louis Blues
Favorite

Buffalo Sabres
The Buffalo Sabres are the -140 moneyline favorite. Risk $140 to win $100 on the Buffalo Sabres at BetMGM. The St. Louis Blues are the +115 underdog at BetMGM. Risk $100 to win $115 on the St. Louis Blues. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 6.5 goals. Risk $100 to win $100. BetMGM has the best under line of 6.5 goals. Risk $120 to win $100. Our tutorial explains more about total bets.

Best Puck Line Betting Odds
Underdog

St. Louis Blues
Favorite

Buffalo Sabres
The Buffalo Sabres have a -1.5 +165 puck line at BetMGM OH. They are the puck line favorite in this matchup. The St. Louis Blues have a +1.5 -200 puck line at BetMGM OH. The St. Louis Blues are the puck line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the St. Louis Blues vs Buffalo Sabres NHL game on Thursday, November 6th, 2025?

The Buffalo Sabres are the -140 moneyline favorite at BetMGM and the St. Louis Blues are the +115 moneyline underdog at BetMGM.

What is the over-under total line for the St. Louis Blues vs Buffalo Sabres NHL game on Thursday, November 6th, 2025?

The best over line is 6.5 +100 goals at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 6.5 -120 goals at BetMGM, and that means you risk $120 to win $100 betting the under.

What is the puck line for the St. Louis Blues vs Buffalo Sabres NHL game on Thursday, November 6th, 2025?

The Buffalo Sabres are -1.5 +165 puck line favorites at BetMGM, while the St. Louis Blues are +1.5 -200 puck line underdogs at BetMGM.

NHL Odds Example

NHL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Blues
Sabres
11/06/25 7:08pm EST
+115-140
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • St. Louis Blues bettors risk $100 to win $115 at +115 odds. The implied probability for St. Louis Blues is 46.51%.
  • Buffalo Sabres bettors risk $100 to win $71.43 at -140 odds. The implied probability for Buffalo Sabres is 58.33%.

St. Louis Blues at Buffalo Sabres Prop Bets

NHL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Blues
Sabres
Both Teams Score 2+ Goals
11/06/25 7:08pm EST
Yes -190No +140Bet
Sabres
Total Goals
STL at BUF
11/06/25 7:08pm EST
3.5 o +1003.5 u -140Bet
Blues
Total Goals
STL at BUF
11/06/25 7:08pm EST
3 o +1003 u -140Bet
Alex Tuch
To Score 3 Goals
STL at BUF
11/06/25 7:08pm EST
Yes +6600Bet
BetMGM Sports Betting BetMGM
Jordan Kyrou
To Score 3 Goals
STL at BUF
11/06/25 7:08pm EST
Yes +8000Bet
Josh Doan
To Score 3 Goals
STL at BUF
11/06/25 7:08pm EST
Yes +8000Bet
Tage Thompson
To Score 3 Goals
STL at BUF
11/06/25 7:08pm EST
Yes +2800Bet

Team Standings

2025-2026 NHL Regular Season Standings - St. Louis Blues, Buffalo Sabres
Team GP W L OTL wPct Pts ROW GF GA Diff Home Away SO L10 Strk
St. Louis Blues29101270.345271073101-28.05-6-45-6-30-24-3-3W1
Buffalo Sabres28111340.3932698496-12.09-5-22-8-22-05-5-0L2

St. Louis Blues & Buffalo Sabres Futures Odds

Latest Stanley Cup odds, if available, for each team. Review odds for other teams and learn how Stanley Cup betting works. See past Championship results and learn how to bet NHL teasers, props and parlays.

St. Louis Blues Stanley Cup Odds
2025-26 St. Louis Blues Stanley Cup Odds

Team
BetMGM Sports Betting BetMGM
Blues
+10000
Bet
Buffalo Sabres Stanley Cup Odds
2025-26 Buffalo Sabres Stanley Cup Odds

Team
BetMGM Sports Betting BetMGM
Sabres
+15000
Bet

St. Louis Blues & Buffalo Sabres Team Pages

Review each team's season point total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the St. Louis Blues vs Buffalo Sabres NHL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, November 6th, 2025 at 7:08 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NHL page, look for the St. Louis Blues vs Buffalo Sabres Game.

    Navigate to the sportsbook's NHL page. Next, look for live or upcoming matchups. Select the St. Louis Blues vs Buffalo Sabres Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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