San Francisco Giants vs Milwaukee Brewers Odds

The Giants will play the Brewers on Wednesday, February 25th, 2026. Your timezone's first pitch time is 3:10 pm EST. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Giants at Brewers Odds


Best Moneyline Betting Odds
Underdog

San Francisco Giants
Favorite

Milwaukee Brewers
The Milwaukee Brewers are the -145 moneyline favorite. Risk $145 to win $100 on the Milwaukee Brewers at BetMGM. The San Francisco Giants are the +120 underdog at BetMGM. Risk $100 to win $120 on the San Francisco Giants. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 11.5 runs. Risk $100 to win $100. BetMGM has the best under line of 11.5 runs. Risk $120 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

San Francisco Giants
Favorite

Milwaukee Brewers
The Milwaukee Brewers have a -1.5 +130 run line at BetMGM OH. They are the run line favorite in this matchup. The San Francisco Giants have a +1.5 -155 run line at BetMGM OH. The San Francisco Giants are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the San Francisco Giants vs Milwaukee Brewers MLB game on Wednesday, February 25th, 2026?

The Milwaukee Brewers are the -145 moneyline favorite at BetMGM and the San Francisco Giants are the +120 moneyline underdog at BetMGM.

What is the over-under total line for the San Francisco Giants vs Milwaukee Brewers MLB game on Wednesday, February 25th, 2026?

The best over line is 11.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 11.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.

What is the run line for the San Francisco Giants vs Milwaukee Brewers MLB game on Wednesday, February 25th, 2026?

The Milwaukee Brewers are -1.5 +130 run line favorites at BetMGM, while the San Francisco Giants are +1.5 -155 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Giants
Brewers
2/25/26 3:10pm EST
+120-145
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Possible Moneyline Outcomes
  • San Francisco Giants bettors risk $100 to win $120 at +120 odds. The implied probability for San Francisco Giants is 45.45%.
  • Milwaukee Brewers bettors risk $100 to win $68.97 at -145 odds. The implied probability for Milwaukee Brewers is 59.18%.

San Francisco Giants at Milwaukee Brewers Prop Bets

MLB Prop Bets
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BetMGM Sports Betting BetMGM
Bet
Giants
Brewers
2/25/26 3:10pm EST
Pending BetMGM

San Francisco Giants & Milwaukee Brewers Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Francisco Giants World Series Odds
2026 San Francisco Giants World Series Odds

Team
BetMGM Sports Betting BetMGM
Giants
+6600
Bet
Milwaukee Brewers World Series Odds
2026 Milwaukee Brewers World Series Odds

Team
BetMGM Sports Betting BetMGM
Brewers
+3000
Bet

San Francisco Giants & Milwaukee Brewers Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Francisco Giants, Milwaukee Brewers
Team W L Pct GB Home Away RS RA Diff Strk L10
* - Milwaukee Brewers97650.5990.052-2945-36806634+172W14-6
e - San Francisco Giants81810.500+16.042-3939-42705684+21W45-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco Giants vs Milwaukee Brewers MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, February 25th, 2026 at 3:10 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the San Francisco Giants vs Milwaukee Brewers Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Francisco Giants vs Milwaukee Brewers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other February 25, 2026 MLB Games

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