Chicago White Sox vs Cleveland Guardians Odds

The White Sox will play the Guardians on Saturday, February 28th, 2026. Your timezone's first pitch time is 3:05 pm EST. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best White Sox at Guardians Odds


Best Moneyline Betting Odds
Underdog

Chicago White Sox
Favorite

Cleveland Guardians
The Cleveland Guardians are the -150 moneyline favorite. Risk $150 to win $100 on the Cleveland Guardians at BetMGM. The Chicago White Sox are the +125 underdog at BetMGM. Risk $100 to win $125 on the Chicago White Sox. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 11.5 runs. Risk $100 to win $100. BetMGM has the best under line of 11.5 runs. Risk $120 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
TBDTBD
Run Line odds are updating, please check back soon.

Matchup Odds FAQs

What is the moneyline for the Chicago White Sox vs Cleveland Guardians MLB game on Saturday, February 28th, 2026?

The Cleveland Guardians are the -150 moneyline favorite at BetMGM and the Chicago White Sox are the +125 moneyline underdog at BetMGM.

What is the over-under total line for the Chicago White Sox vs Cleveland Guardians MLB game on Saturday, February 28th, 2026?

The best over line is 11.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 11.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
White Sox
Guardians
2/28/26 3:05pm EST
+125-150
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Chicago White Sox bettors risk $100 to win $125 at +125 odds. The implied probability for Chicago White Sox is 44.44%.
  • Cleveland Guardians bettors risk $100 to win $66.67 at -150 odds. The implied probability for Cleveland Guardians is 60%.

Chicago White Sox at Cleveland Guardians Prop Bets

MLB Prop Bets
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Bet
White Sox
Guardians
2/28/26 3:05pm EST
Pending BetMGM

Chicago White Sox & Cleveland Guardians Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Chicago White Sox World Series Odds
2026 Chicago White Sox World Series Odds

Team
BetMGM Sports Betting BetMGM
White Sox
+50000
Bet
Cleveland Guardians World Series Odds
2026 Cleveland Guardians World Series Odds

Team
BetMGM Sports Betting BetMGM
Guardians
+5000
Bet

Chicago White Sox & Cleveland Guardians Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Chicago White Sox, Cleveland Guardians
Team W L Pct GB Home Away RS RA Diff Strk L10
x - Cleveland Guardians88740.543+9.045-3643-38643649-6W27-3
e - Chicago White Sox601020.370+37.033-4827-54647742-95W13-7

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Chicago White Sox vs Cleveland Guardians MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, February 28th, 2026 at 3:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Chicago White Sox vs Cleveland Guardians Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago White Sox vs Cleveland Guardians Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other February 28, 2026 MLB Games

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