Minnesota Twins vs Cleveland Guardians Odds

The Twins will play the Guardians on Thursday, May 1st, 2025. Your timezone's first pitch time is 1:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Minnesota Twins have a 88.67 power ranking. The power ranking for the Cleveland Guardians is 90.67.
  • Visiting Minnesota Twins - The Minnesota Twins have a 4-12 record as a visiting team, ranking them 7th Overall for visiting team wins.
  • Home Cleveland Guardians - The Cleveland Guardians have a 10-5 record as a home team. They rank 6th for home team wins in the Overall standings.
  • Runs Scored - The Minnesota Twins currently stand 16th (120) Overall, with the Cleveland Guardians ranking 20th (114) for runs scored.
  • Runs Allowed - The Minnesota Twins are 19th (115) Overall for runs allowed. The Cleveland Guardians stand 9th (139) for runs allowed.
  • Team Streaks - The Minnesota Twins have lost their last 2 games. Meanwhile, the Cleveland Guardians have won their last 2 games.
  • Team Records - The Minnesota Twins have a 13-18 Overall record (6.0 GB American Central Division), with the Cleveland Guardians possessing a 17-13 Overall standing (1.5 GB American Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Twins be facing the Guardians in Cleveland on Thursday... Their record be pitiful, but they be on a winning streak lately...

The Guardians be holdin' their own with a better overall record... But don't let that fool ye, the Twins be ready to plunder... SportsBetting3.com be the place to bet on this game, me hearties...

So raise the Jolly Roger and review the odds below, it's game time!

Best Twins at Guardians Odds


Best Moneyline Betting Odds
Underdog

Cleveland Guardians
Favorite

Minnesota Twins
The Minnesota Twins are the -125 moneyline favorite. Risk $125 to win $100 on the Minnesota Twins at BetMGM. The Cleveland Guardians are the +105 underdog at BetMGM. Risk $100 to win $105 on the Cleveland Guardians. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 9 runs. Risk $118 to win $100. BetMGM has the best under line of 9 runs. Risk $102 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cleveland Guardians
Favorite

Minnesota Twins
The Minnesota Twins have a -1.5 +135 run line at BetMGM OH. They are the run line favorite in this matchup. The Cleveland Guardians have a +1.5 -160 run line at BetMGM OH. The Cleveland Guardians are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Minnesota Twins vs Cleveland Guardians MLB game on Thursday, May 1st, 2025?

The Minnesota Twins are the -125 moneyline favorite at BetMGM and the Cleveland Guardians are the +105 moneyline underdog at BetMGM.

What is the over-under total line for the Minnesota Twins vs Cleveland Guardians MLB game on Thursday, May 1st, 2025?

The best over line is 9 -118 runs at BetMGM, which means you risk $118 to win $100 betting the over. The best under line is 9 -102 runs at BetMGM, and that means you risk $102 to win $100 betting the under.

What is the run line for the Minnesota Twins vs Cleveland Guardians MLB game on Thursday, May 1st, 2025?

The Minnesota Twins are -1.5 +135 run line favorites at BetMGM, while the Cleveland Guardians are +1.5 -160 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Twins
Guardians
5/01/25 1:10pm EDT
-125+105
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Cleveland Guardians bettors risk $100 to win $105 at +105 odds. The implied probability for Cleveland Guardians is 48.78%.
  • Minnesota Twins bettors risk $100 to win $80 at -125 odds. The implied probability for Minnesota Twins is 55.56%.

Minnesota Twins at Cleveland Guardians Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Twins
Guardians
First Team to Score
5/01/25 1:10pm EDT
-175+135Bet
Twins
Guardians
Tie
1st Inning Winner
5/01/25 1:10pm EDT
+260+280-118Bet
Twins
Guardians
Tie
First 3 Innings Winner
5/01/25 1:10pm EDT
+125+145+333Bet
Twins
Guardians
To Extra Innings
5/01/25 1:10pm EDT
Yes +800No -1400Bet
BetMGM Sports Betting BetMGM
Twins
Guardians
1st Team to Score Will Win
5/01/25 1:10pm EDT
Yes -250No +190Bet
Guardians
Total Runs
MIN at CLE
5/01/25 1:10pm EDT
4.5 o +1054.5 u -140Bet
Twins
Total Runs
MIN at CLE
5/01/25 1:10pm EDT
4.5 o -1254.5 u -105Bet
Ben Lively
Strikeouts Thrown
MIN at CLE
5/01/25 1:10pm EDT
4.5 o +1154.5 u -150Bet
BetMGM Sports Betting BetMGM
Simeon Woods Richardson
Strikeouts Thrown
MIN at CLE
5/01/25 1:10pm EDT
4.5 o +1054.5 u -140Bet

Minnesota Twins & Cleveland Guardians Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Minnesota Twins World Series Odds
2025 Minnesota Twins World Series Odds

Team
BetMGM Sports Betting BetMGM
Twins
+3000
Bet
Cleveland Guardians World Series Odds
2025 Cleveland Guardians World Series Odds

Team
BetMGM Sports Betting BetMGM
Guardians
+5500
Bet

Minnesota Twins & Cleveland Guardians Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Minnesota Twins, Cleveland Guardians
Team W L Pct GB Home Away RS RA Diff Strk L10
Minnesota Twins30240.556+5.018-812-16216185+31W16-4
Cleveland Guardians29250.537+6.014-1015-15216236-20L34-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Minnesota Twins vs Cleveland Guardians MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, May 1st, 2025 at 1:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Minnesota Twins vs Cleveland Guardians Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Minnesota Twins vs Cleveland Guardians Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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