The Diamondbacks will play the Cardinals on Sunday, May 25th, 2025. Your timezone's first pitch time is 2:15 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - As the 2025 season continues, the Arizona Diamondbacks possess a 89.00 SportsBetting3.com power ranking. The St. Louis Cardinals now have a 94.33 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
- Visiting Arizona Diamondbacks - The Arizona Diamondbacks head into this matchup with a 13-13 record as a visiting team. This standing ranks them 4th Overall for visiting team wins.
- Home St. Louis Cardinals - The St. Louis Cardinals will throw the first pitch possessing a 18-8 home team record. That puts them 2nd for home team wins in the Overall MLB standings.
- Runs Scored - Arizona Diamondbacks batters have produced 264 runs, ranking them 5th Overall, with the St. Louis Cardinals ranking 6th (250) for runs scored.
- Runs Allowed - Arizona Diamondbacks pitchers and fielders have allowed 262 runs, ranking them 6th Overall for runs allowed. Meanwhile, the St. Louis Cardinals now rank 16th Overall, allowing 208 runs.
- Team Streaks - The Arizona Diamondbacks have lost their last 4 games. Their opponent, the St. Louis Cardinals have won their last 2 games.
- Team Records - Let's review each team's records. The Arizona Diamondbacks have a 26-26 Overall record (6.5 GB National West Division), with the St. Louis Cardinals notching a 29-23 Overall standing (2.0 GB National Central Division).
Captain Shady Lines
A broken compass is right at least twice a day.

Avast ye scurvy dogs! The Diamondbacks be facing the Cardinals on Sunday...
Ye Diamondbacks be sailing with a 0.500 win percentage, aye...
The Cardinals be ahead with a 0.558 win percentage, blast it all!
Will the Diamondbacks plunder a victory or walk the plank? Only time will tell...
Check out this game's prop bets below, bet on MLB baseball at legal US sportsbooks...
Review each team's standing at the bottom of the page. Arrrrr!
Best Diamondbacks at Cardinals Odds
Underdog Arizona Diamondbacks | Favorite St. Louis Cardinals |
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Over | Under |
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Underdog Arizona Diamondbacks | Favorite St. Louis Cardinals |
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Matchup Odds FAQs
The St. Louis Cardinals are the -125 moneyline favorite at BetMGM and the Arizona Diamondbacks are the +105 moneyline underdog at BetMGM.
The best over line is 7.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 7.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.
The St. Louis Cardinals are -1.5 +170 run line favorites at BetMGM, while the Arizona Diamondbacks are +1.5 -210 run line underdogs at BetMGM.
MLB Odds Example
Game |
![]() Bet |
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Diamondbacks
Cardinals
5/25/25 2:15pm EDT | +105-125 |
- Arizona Diamondbacks bettors risk $100 to win $105 at +105 odds. The implied probability for Arizona Diamondbacks is 48.78%.
- St. Louis Cardinals bettors risk $100 to win $80 at -125 odds. The implied probability for St. Louis Cardinals is 55.56%.
Arizona Diamondbacks at St. Louis Cardinals Prop Bets
![]() Bet |
|
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Diamondbacks
Cardinals
First Team to Score
5/25/25 2:15pm EDT | -140+110Bet |
Diamondbacks
Cardinals
Tie
1st Inning Winner
5/25/25 2:15pm EDT | +325+320-155Bet |
Diamondbacks
Cardinals
Tie
First 3 Innings Winner
5/25/25 2:15pm EDT | +154+140+250Bet |
Diamondbacks
Cardinals
To Extra Innings
5/25/25 2:15pm EDT | Yes +700No -1100Bet |
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Diamondbacks
Cardinals
1st Team to Score Will Win
5/25/25 2:15pm EDT | Yes -250No +190Bet |
Diamondbacks
Total Runs
ARI at STL 5/25/25 2:15pm EDT | 3.5 o -1103.5 u -118Bet |
Cardinals
Total Runs
ARI at STL 5/25/25 2:15pm EDT | 3.5 o -1183.5 u -110Bet |
Brandon Pfaadt
Strikeouts Thrown
ARI at STL 5/25/25 2:15pm EDT | 4.5 o +1154.5 u -155Bet |
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Sonny Gray
Strikeouts Thrown
ARI at STL 5/25/25 2:15pm EDT | 5.5 o -1305.5 u +100Bet |
Arizona Diamondbacks & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Arizona Diamondbacks World Series Odds
Team | ![]() |
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Diamondbacks | +6600 Bet |
Team | ![]() |
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Cardinals | +6600 Bet |
Arizona Diamondbacks & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
---|---|---|---|---|---|---|---|---|---|---|---|
St. Louis Cardinals | 30 | 24 | 0.556 | +5.0 | 19-8 | 11-16 | 256 | 216 | +40 | L1 | 6-4 |
Arizona Diamondbacks | 27 | 27 | 0.500 | +8.0 | 14-13 | 13-14 | 272 | 266 | +6 | W1 | 4-6 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Arizona Diamondbacks vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, May 25th, 2025 at 2:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Arizona Diamondbacks vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Arizona Diamondbacks vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 25, 2025 MLB Games
- Cleveland Guardians vs Detroit Tigers - 5/25/25 11:35am EDT
- Baltimore Orioles vs Boston Red Sox - 5/25/25 1:35pm EDT
- Milwaukee Brewers vs Pittsburgh Pirates - 5/25/25 1:35pm EDT
- San Francisco Giants vs Washington Nationals - 5/25/25 1:35pm EDT
- Chicago Cubs vs Cincinnati Reds - 5/25/25 1:40pm EDT
- Toronto Blue Jays vs Tampa Bay Rays - 5/25/25 1:40pm EDT
- Texas Rangers vs Chicago White Sox - 5/25/25 2:10pm EDT
- Seattle Mariners vs Houston Astros - 5/25/25 2:10pm EDT
- Kansas City Royals vs Minnesota Twins - 5/25/25 2:10pm EDT
- New York Yankees vs Colorado Rockies - 5/25/25 3:10pm EDT
- Philadelphia Phillies vs Oakland Athletics - 5/25/25 4:05pm EDT
- Miami Marlins vs Los Angeles Angels - 5/25/25 4:07pm EDT
- San Diego Padres vs Atlanta Braves - 5/25/25 4:10pm EDT
- Los Angeles Dodgers vs New York Mets - 5/25/25 7:10pm EDT