Kansas City Royals vs San Diego Padres Odds

The Royals will play the Padres on Sunday, June 22nd, 2025. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the Kansas City Royals possess a 91.33 SportsBetting3.com power ranking. The San Diego Padres now have a 95.00 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting Kansas City Royals - The Kansas City Royals head into this matchup with a 12-16 record as a visiting team. This standing ranks them 6th Overall for visiting team wins.
  • Home San Diego Padres - The San Diego Padres will throw the first pitch possessing a 17-8 home team record. That puts them 4th for home team wins in the Overall MLB standings.
  • Runs Scored - Kansas City Royals batters have produced 183 runs, ranking them 24th Overall, with the San Diego Padres ranking 18th (217) for runs scored.
  • Runs Allowed - Kansas City Royals pitchers and fielders have allowed 184 runs, ranking them 26th Overall for runs allowed. Meanwhile, the San Diego Padres now rank 22nd Overall, allowing 199 runs.
  • Team Streaks - The Kansas City Royals lost their last game. Their opponent, the San Diego Padres have won their last 2 games.
  • Team Records - Let's review each team's records. The Kansas City Royals have a 29-26 Overall record (7.0 GB American Central Division), with the San Diego Padres notching a 30-22 Overall standing (2.0 GB National West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye landlubbers! The Royals be facing the Padres in San Diego...

The Royals be lookin' to turn the tide with a win on Sunday...

But the Padres be standin' strong with a better record and win percentage...

Will the Royals plunder a victory or will the Padres send 'em packin'?

Check out this game's prop bets below, bet on MLB baseball at legal US sportsbooks...

Review each team's standing at the bottom of the page...yo ho ho...

Best Royals at Padres Odds


Best Moneyline Betting Odds
Underdog

San Diego Padres
Favorite

Kansas City Royals
The Kansas City Royals are the -115 moneyline favorite. Risk $115 to win $100 on the Kansas City Royals at BetMGM. The San Diego Padres are the -105 underdog at BetMGM. Risk $105 to win $100 on the San Diego Padres. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8.5 runs. Risk $118 to win $100. BetMGM has the best under line of 8.5 runs. Risk $102 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

San Diego Padres
Favorite

Kansas City Royals
The Kansas City Royals have a -1.5 +150 run line at BetMGM OH. They are the run line favorite in this matchup. The San Diego Padres have a +1.5 -180 run line at BetMGM OH. The San Diego Padres are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Kansas City Royals vs San Diego Padres MLB game on Sunday, June 22nd, 2025?

The Kansas City Royals are the -115 moneyline favorite at BetMGM and the San Diego Padres are the -105 moneyline underdog at BetMGM.

What is the over-under total line for the Kansas City Royals vs San Diego Padres MLB game on Sunday, June 22nd, 2025?

The best over line is 8.5 -118 runs at BetMGM, which means you risk $118 to win $100 betting the over. The best under line is 8.5 -102 runs at BetMGM, and that means you risk $102 to win $100 betting the under.

What is the run line for the Kansas City Royals vs San Diego Padres MLB game on Sunday, June 22nd, 2025?

The Kansas City Royals are -1.5 +150 run line favorites at BetMGM, while the San Diego Padres are +1.5 -180 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Royals
Padres
6/22/25 4:10pm EDT
-115-105
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Possible Moneyline Outcomes
  • San Diego Padres bettors risk $100 to win $95.24 at -105 odds. The implied probability for San Diego Padres is 51.22%.
  • Kansas City Royals bettors risk $100 to win $86.96 at -115 odds. The implied probability for Kansas City Royals is 53.49%.

Kansas City Royals at San Diego Padres Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Royals
Padres
First Team to Score
6/22/25 4:10pm EDT
-165+130Bet
Royals
Padres
Tie
1st Inning Winner
6/22/25 4:10pm EDT
+270+290-125Bet
Royals
Padres
Tie
First 3 Innings Winner
6/22/25 4:10pm EDT
+130+140+310Bet
Royals
Padres
To Extra Innings
6/22/25 4:10pm EDT
Yes +775No -1400Bet
BetMGM Sports Betting BetMGM
Royals
Padres
1st Team to Score Will Win
6/22/25 4:10pm EDT
Yes -250No +190Bet
Royals
Total Runs
KAN at SDG
6/22/25 4:10pm EDT
4.5 o +1004.5 u -130Bet
Padres
Total Runs
KAN at SDG
6/22/25 4:10pm EDT
3.5 o -1503.5 u +115Bet
Randy Vasquez
Strikeouts Thrown
KAN at SDG
6/22/25 4:10pm EDT
2.5 o -1552.5 u +120Bet
BetMGM Sports Betting BetMGM
Seth Lugo
Strikeouts Thrown
KAN at SDG
6/22/25 4:10pm EDT
4.5 o +1054.5 u -140Bet

Kansas City Royals & San Diego Padres Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Kansas City Royals World Series Odds
2025 Kansas City Royals World Series Odds

Team
BetMGM Sports Betting BetMGM
Royals
+15000
Bet
San Diego Padres World Series Odds
2025 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM
Padres
+3500
Bet

Kansas City Royals & San Diego Padres Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Kansas City Royals, San Diego Padres
Team W L Pct GB Home Away RS RA Diff Strk L10
San Diego Padres30220.577+4.017-813-14217199+18W23-7
Kansas City Royals29260.527+6.517-1012-16183184-1L14-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Kansas City Royals vs San Diego Padres MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, June 22nd, 2025 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Kansas City Royals vs San Diego Padres Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Kansas City Royals vs San Diego Padres Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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