St. Louis Cardinals vs Washington Nationals Odds

The Cardinals will play the Nationals on Wednesday, April 8th, 2026. Your timezone's first pitch time is 4:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The St. Louis Cardinals have a 90.33 power ranking. The power ranking for the Washington Nationals is 92.00.
  • Visiting St. Louis Cardinals - The St. Louis Cardinals have a 1-3 record as a visiting team, ranking them 5th Overall for visiting team wins.
  • Home Washington Nationals - The Washington Nationals have a 1-3 record as a home team. They rank 5th for home team wins in the Overall standings.
  • Runs Scored - The St. Louis Cardinals currently stand 11th (46) Overall, with the Washington Nationals ranking 4th (64) for runs scored.
  • Runs Allowed - The St. Louis Cardinals are 6th (55) Overall for runs allowed. The Washington Nationals stand 1st (65) for runs allowed.
  • Team Streaks - The St. Louis Cardinals lost their last game. Meanwhile, the Washington Nationals won their last game.
  • Team Records - The St. Louis Cardinals have a 5-5 Overall record (2.5 GB National Central Division), with the Washington Nationals possessing a 4-6 Overall standing (2.5 GB National East Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arrr, mateys! The St. Louis Cardinals be facing the Washington Nationals on Wednesday...

Ye Cardinals be holdin' a 5-5 record and a 0.500 win percentage...

The Nationals be sittin' with a 4-6 record and a 0.400 win percentage...

If ye be lookin' to make some gold doubloons, head over to SportsBetting3.com...

Bet on this game and review the odds below, me hearties! May the best team win!

Best Cardinals at Nationals Odds


Best Moneyline Betting Odds
Underdog

Washington Nationals
Favorite

St. Louis Cardinals
The St. Louis Cardinals are the -120 moneyline favorite. Risk $120 to win $100 on the St. Louis Cardinals at BetMGM. The Washington Nationals are the +100 underdog at BetMGM. Risk $100 to win $100 on the Washington Nationals. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8.5 runs. Risk $105 to win $100. BetMGM has the best under line of 8.5 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Washington Nationals
Favorite

St. Louis Cardinals
The St. Louis Cardinals have a -1.5 +140 run line at BetMGM OH. They are the run line favorite in this matchup. The Washington Nationals have a +1.5 -170 run line at BetMGM OH. The Washington Nationals are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the St. Louis Cardinals vs Washington Nationals MLB game on Wednesday, April 8th, 2026?

The St. Louis Cardinals are the -120 moneyline favorite at BetMGM and the Washington Nationals are the +100 moneyline underdog at BetMGM.

What is the over-under total line for the St. Louis Cardinals vs Washington Nationals MLB game on Wednesday, April 8th, 2026?

The best over line is 8.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 8.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the St. Louis Cardinals vs Washington Nationals MLB game on Wednesday, April 8th, 2026?

The St. Louis Cardinals are -1.5 +140 run line favorites at BetMGM, while the Washington Nationals are +1.5 -170 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Cardinals
Nationals
4/08/26 4:05pm EDT
-120+100
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Washington Nationals bettors risk $100 to win $100 at +100 odds. The implied probability for Washington Nationals is 50%.
  • St. Louis Cardinals bettors risk $100 to win $83.33 at -120 odds. The implied probability for St. Louis Cardinals is 54.55%.

St. Louis Cardinals at Washington Nationals Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Cardinals
Nationals
First Team to Score
4/08/26 4:05pm EDT
-175+135Bet
Cardinals
Nationals
Tie
1st Inning Winner
4/08/26 4:05pm EDT
+270+325-135Bet
Cardinals
Nationals
Tie
First 3 Innings Winner
4/08/26 4:05pm EDT
+125+154+290Bet
Cardinals
Nationals
To Extra Innings
4/08/26 4:05pm EDT
Yes +750No -1200Bet
BetMGM Sports Betting BetMGM
Cardinals
Nationals
1st Team to Score Will Win
4/08/26 4:05pm EDT
Yes -250No +190Bet
Cardinals
Total Runs
STL at WAS
4/08/26 4:05pm EDT
4.5 o +1054.5 u -140Bet
Nationals
Total Runs
STL at WAS
4/08/26 4:05pm EDT
3.5 o -1303.5 u +100Bet

St. Louis Cardinals & Washington Nationals Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

St. Louis Cardinals World Series Odds
2026 St. Louis Cardinals World Series Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+12500
Bet
Washington Nationals World Series Odds
2026 Washington Nationals World Series Odds

Team
BetMGM Sports Betting BetMGM
Nationals
+50000
Bet

St. Louis Cardinals & Washington Nationals Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - St. Louis Cardinals, Washington Nationals
Team W L Pct GB Home Away RS RA Diff Strk L10
St. Louis Cardinals1490.609+2.07-57-4111119-8W16-4
Washington Nationals11130.458+5.53-88-5136147-11W15-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the St. Louis Cardinals vs Washington Nationals MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 8th, 2026 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the St. Louis Cardinals vs Washington Nationals Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the St. Louis Cardinals vs Washington Nationals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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