The Orioles will play the White Sox on Wednesday, September 17th, 2025. Your timezone's first pitch time is 2:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Orioles at White Sox Odds
| Underdog Chicago White Sox | Favorite Baltimore Orioles |
|---|---|
| Over | Under |
|---|---|
| Underdog Chicago White Sox | Favorite Baltimore Orioles |
|---|---|
Matchup Odds FAQs
The Baltimore Orioles are the -130 moneyline favorite at BetMGM and the Chicago White Sox are the +110 moneyline underdog at BetMGM.
The best over line is 8 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 8 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The Baltimore Orioles are -1.5 +135 run line favorites at BetMGM, while the Chicago White Sox are +1.5 -160 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Orioles
White Sox
2:10pm EDT | -130+110 |
- Chicago White Sox bettors risk $100 to win $110 at +110 odds. The implied probability for Chicago White Sox is 47.62%.
- Baltimore Orioles bettors risk $100 to win $76.92 at -130 odds. The implied probability for Baltimore Orioles is 56.52%.
Baltimore Orioles at Chicago White Sox Prop Bets
| BetMGM Bet |
|
|---|---|
Orioles
White Sox
First Team to Score
2:10pm EDT | -175+135Bet |
Orioles
White Sox
Tie
1st Inning Winner
2:10pm EDT | +275+333-140Bet |
Orioles
White Sox
Tie
First 3 Innings Winner
2:10pm EDT | +130+160+270Bet |
Orioles
White Sox
To Extra Innings
2:10pm EDT | Yes +750No -1200Bet |
| BetMGM | |
Orioles
White Sox
1st Team to Score Will Win
2:10pm EDT | Yes -250No +190Bet |
Orioles
Total Runs
BAL at CWS 2:10pm EDT | 4.5 o +1054.5 u -140Bet |
Martin Perez
Strikeouts Thrown
BAL at CWS 2:10pm EDT | 4.5 o -1354.5 u +105Bet |
Tyler Wells
Strikeouts Thrown
BAL at CWS 2:10pm EDT | 5.5 o +1305.5 u -165Bet |
Baltimore Orioles & Chicago White Sox Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Baltimore Orioles World Series OddsNo World Series TM Baltimore Orioles YR: futures available
Chicago White Sox World Series OddsNo World Series TM Chicago White Sox YR: futures available
Baltimore Orioles & Chicago White Sox Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Baltimore Orioles | 70 | 80 | 0.467 | +21.0 | 36-38 | 34-42 | 639 | 730 | -91 | W1 | 6-4 |
| e - Chicago White Sox | 57 | 94 | 0.377 | +34.5 | 32-44 | 25-50 | 601 | 687 | -86 | L4 | 4-6 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Baltimore Orioles vs Chicago White Sox MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, September 17th, 2025 at 2:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Baltimore Orioles vs Chicago White Sox Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Baltimore Orioles vs Chicago White Sox Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 17, 2025 MLB Games
- Chicago Cubs vs Pittsburgh Pirates - 12:35pm EDT
- Cincinnati Reds vs St. Louis Cardinals - 1:15pm EDT
- San Francisco Giants vs Arizona Diamondbacks - 3:40pm EDT
- Atlanta Braves vs Washington Nationals - 4:05pm EDT
- Cleveland Guardians vs Detroit Tigers - 6:40pm EDT
- Oakland Athletics vs Boston Red Sox - 6:45pm EDT
- Toronto Blue Jays vs Tampa Bay Rays - 7:05pm EDT
- San Diego Padres vs New York Mets - 7:10pm EDT
- Seattle Mariners vs Kansas City Royals - 7:40pm EDT
- Los Angeles Angels vs Milwaukee Brewers - 7:40pm EDT
- New York Yankees vs Minnesota Twins - 7:40pm EDT
- Texas Rangers vs Houston Astros - 8:10pm EDT
- Miami Marlins vs Colorado Rockies - 8:40pm EDT
- Philadelphia Phillies vs Los Angeles Dodgers - 10:10pm EDT