West Virginia vs Clemson Basketball Odds

The Mountaineers will play the Tigers on Friday, November 21st, 2025. Your timezone's tip off time is 6:30 pm EST. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

The West Virginia and Clemson basketball teams will play on Friday, November 21st, 2025 as the 2025-26 college basketball season continues to roll along. Now that both teams have a few games under their belts, let’s size up this matchup by looking at some performance metrics and key stats.

  • SportsBetting3.com Power Rankings - West Virginia currently has a 100.00 conference power ranking so far in the 2025-26 season. The SportsBetting3.com conference power ranking for Clemson is 98.33.
  • Away West Virginia - West Virginia heads into this game with a 0-0 record as an away team, ranking them 2nd in the Big 12 Conference for away team wins.
  • Home Clemson - Clemson will host West Virginia sporting a 4-0 record as a home team. They currently rank 2nd in the ACC Conference for home team wins for the 2025-26 season.
  • Conference Win Percentage - West Virginia currently ranks 1st (0.000) in the Big 12 Conference, with Clemson now standing 1st (0.000) for their conference win percentage in the 2025 ACC Conference for the 2025-26 college basketball season.
  • Overall Win Percentage - West Virginia has a 1.000 overall win percentage. Their opponent, Clemson, has a 0.800 overall win percentage.
  • Team Records - West Virginia has a 5-0 regular season overall record. Clemson has notched a 4-1 standing so far in the 2025-26 college basketball season.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Hocus pocus, West Virginia undefeated, facing Clemson with only one loss this season.

Big game for both teams, conference records crucial for tournament seeding next year.

West Virginia riding a 5-game winning streak, Clemson looking to bounce back.

Our point spread, total, and moneyline tables show the best lines and odds for this matchup. Place a bet at BetMGM or BetRivers. Review each team’s futures odds and current standings below.

Best Mountaineers at Tigers Odds


Best Point Spread Betting Odds
Underdog

West Virginia
Favorite

Clemson
Clemson has a -3.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. West Virginia has a +3.5 -110 point spread at BetMGM OH. West Virginia is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 132.5 points. Risk $115 to win $100. BetMGM has the best under line of 132.5 points. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
TBDTBD
Moneyline odds are updating, please check back soon.

Matchup Odds FAQs

What is the point spread for the West Virginia vs Clemson College Basketball game on Friday, November 21st, 2025?

Clemson is a -3.5 -110 point spread favorite at BetMGM, while West Virginia is a +3.5 -110 point spread underdog at BetMGM.

What is the over-under total line for the West Virginia vs Clemson College Basketball game on Friday, November 21st, 2025?

The best over line is 132.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 132.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
West Virginia
Clemson
11/21/25 6:30pm EST
+3.5 -110-3.5 -110
Bet $100 at BetMGM Ohio
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Underdog West Virginia - West Virginia bettors risk $100 to win $90.91 at -110 odds.

A +3.5 West Virginia underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.

Favorite Clemson - Clemson bettors risk $100 to win $90.91 at -110 odds.

A -3.5 Clemson favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.

West Virginia at Clemson Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
West Virginia
Clemson
11/21/25 6:30pm EST
Pending BetMGM

Team Standings

2025-2026 College Basketball Regular Season Standings - West Virginia, Clemson
Team W-L Win% Home Away Conf CGB Conf% Strk
ACC
Clemson6-10.8574-00-10-0-0.000W3
Big 12
West Virginia5-20.7145-00-00-0-0.000L2

West Virginia & Clemson Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

West Virginia Championship Odds
2025-26 West Virginia NCAA Men's Basketball Tournament Odds

Team
BetMGM Sports Betting BetMGM
West Virginia
+35000
Bet
Clemson Championship Odds
2025-26 Clemson NCAA Men's Basketball Tournament Odds

Team
BetMGM Sports Betting BetMGM
Clemson
+20000
Bet

West Virginia & Clemson Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the West Virginia vs Clemson College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, November 21st, 2025 at 6:30 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the West Virginia vs Clemson Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the West Virginia vs Clemson Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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