The Tigers will play the Rebels on Saturday, September 27th, 2025. The matchup takes place at Vaught-Hemingway Stadium. Watch this exciting Week 5 matchup at 3:30 pm EDT. Check local listings for coverage on ABC.
Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.
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Table of Contents
- Matchup Stats
- Paddy O'Parlay
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Team Schedules & Results
- Other Games Today
Key Matchup Stats
We're now well into the 2025 college football season. Week 5 action features a matchup between LSU and Ole Miss taking place at Vaught-Hemingway Stadium. The following are some key season stats to help you size up this game.
- SportsBetting3.com Power Rankings - LSU has a 97.00 conference power ranking for the 2025 season. The conference power ranking for Ole Miss is 99.00.
- Away LSU - Heading into Week 5, LSU currently has a 1-0 record as an away team for the 2025 regular season. This ranks them 2nd in the SEC Conference for away team wins. Watch this stat carefully as the season progresses.
- Home Ole Miss - Ole Miss has a 3-0 record as a home team. Looking ahead to this 2025 Week 5 matchup, they rank 2nd in the SEC Conference for home team wins. Like the LSU away record and ranking, you should continually keep tabs on this stat.
- Points Scored - For the 2025 season, LSU ranks 11th (116) in the SEC Conference, with Ole Miss currently ranking 4th (179) for points scored in the SEC Conference.
- Points Against - Also in 2025, LSU stands 14th (37) in the SEC Conference for points scored by opponents in 2025. Ole Miss sits at 5th (75) in the SEC Conference for points against in the 2025 season so far.
- Team Records - LSU has a 4-0 overall record for the 2025 regular season, with Ole Miss currently 4-0 for the 2025 NCAAF regular season.
Paddy O'Parlay
The "Sports Network" talking heads have nothing on my Irish arse!
Get ready for a wild showdown as LSU clashes with Ole Miss on Saturday night!
Vaught-Hemingway Stadium will be rocking for this Week 5 showdown between two undefeated teams.
The SportsBetting3.com Power Rankings favor Ole Miss slightly over LSU in this matchup.
Both teams come into this game with perfect 4-0 records, making this a crucial showdown.
Bet this game at BetRivers, or BetMGM, review this game's prop bets, and compare the odds below for an exciting matchup!
Best Tigers at Rebels Odds
| Underdog LSU | Favorite Ole Miss |
|---|---|
| Over | Under |
|---|---|
| Underdog LSU | Favorite Ole Miss |
|---|---|
Matchup Odds FAQs
Ole Miss is a -1.5 -115 point spread favorite at BetMGM, while LSU is a +1.5 -105 point spread underdog at BetMGM.
The best over line is 57.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 57.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
Ole Miss is a -130 moneyline favorite at BetMGM and LSU is a +110 moneyline underdog at BetMGM.
College Football Odds Example
|
Game |
 BetMGMBet |
|---|---|
LSU
Ole Miss
9/27/25 3:30pm EDT | +1.5 -105-1.5 -115 |
Underdog LSU - LSU bettors risk $100 to win $95.24 at -105 odds.
A +1.5 LSU underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.
Favorite Ole Miss - Ole Miss bettors risk $100 to win $86.96 at -115 odds.
A -1.5 Ole Miss favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.
LSU at Ole Miss Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
LSU
Ole Miss
No Touchdown
To Score 1st Touchdown
9/27/25 3:30pm EDT | +100-145+10000Bet |
LSU
Ole Miss
Game to Overtime
9/27/25 3:30pm EDT | Yes +950No -5000Bet |
LSU
Ole Miss
Both Teams Score 10+
9/27/25 3:30pm EDT | Yes -3000No +1000Bet |
LSU
Ole Miss
Both Teams Score 20+
9/27/25 3:30pm EDT | Yes -225No +175Bet |
| BetMGM | |
LSU
Ole Miss
Both Teams Score 30+
9/27/25 3:30pm EDT | Yes +240No -325Bet |
Recent Meetings Since 2021
| Week | Game | Result | Margin |
|---|---|---|---|
| 2025 Week 5 | LSU vs Ole Miss Saturday, September 27th, 2025 | MISS 24, LSU 19 Vaught-Hemingway Stadium | Ole Miss by 5 |
| 2024 Week 7 | Ole Miss vs LSU Saturday, October 12th, 2024 | LSU 29, MISS 26 (OT) Tiger Stadium (LA) | LSU by 3 |
| 2023 Week 5 | LSU vs Ole Miss Saturday, September 30th, 2023 | MISS 55, LSU 49 Vaught-Hemingway Stadium | Ole Miss by 6 |
| 2022 Week 8 | Ole Miss vs LSU Saturday, October 22nd, 2022 | LSU 45, MISS 20 Tiger Stadium (LA) | LSU by 25 |
| 2021 Week 8 | LSU vs Ole Miss Saturday, October 23rd, 2021 | MISS 31, LSU 17 Vaught-Hemingway Stadium | Ole Miss by 14 |
Team Standings
| Team | Conf | Conf% | W | L | PF | PA | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|---|
| #7 Ole Miss | 5-1 | 0.833 | 8 | 1 | 326 | 198 | 6-0 | 2-1 | W2 |
| LSU | 2-3 | 0.400 | 5 | 3 | 204 | 151 | 4-1 | 1-2 | L2 |
LSU & Ole Miss Futures Odds
Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.
LSU Championship Odds|
Team | BetMGM |
|---|---|
| LSU | +50000 Bet |
|
Team | BetMGM |
|---|---|
| Ole Miss | +2000 Bet |
LSU & Ole Miss Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Schedules & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | LSU vs Clemson | LSU 17, CLEM 10 Saturday, August 30th, 2025 |
| Week 2 | Louisiana Tech vs LSU | LSU 23, LT 7 Saturday, September 6th, 2025 |
| Week 3 | Florida vs LSU | LSU 20, FLA 10 Saturday, September 13th, 2025 |
| Week 4 | Southeastern Louisiana vs LSU | LSU 56, SELA 10 Saturday, September 20th, 2025 |
| Week 5 | LSU vs Ole Miss | MISS 24, LSU 19 Saturday, September 27th, 2025 |
| Week 7 | South Carolina vs LSU | LSU 20, SC 10 Saturday, October 11th, 2025 |
| Week 8 | LSU vs Vanderbilt | VAN 31, LSU 24 Saturday, October 18th, 2025 |
| Week 9 | Texas A&M vs LSU | Saturday, October 25th, 2025 7:30 pm EDT |
| Week 11 | LSU vs Alabama | Saturday, November 8th, 2025 12:00 am EST |
| Week 12 | Arkansas vs LSU | Saturday, November 15th, 2025 12:00 am EST |
| Week 13 | Western Kentucky vs LSU | Saturday, November 22nd, 2025 12:00 am EST |
| Week 14 | LSU vs Oklahoma | Saturday, November 29th, 2025 12:00 am EST |
| Week | Matchup | Date & Result |
|---|---|---|
| Week 1 | Georgia State vs Ole Miss | MISS 63, GAST 7 Saturday, August 30th, 2025 |
| Week 2 | Ole Miss vs Kentucky | MISS 30, UK 23 Saturday, September 6th, 2025 |
| Week 3 | Arkansas vs Ole Miss | MISS 41, ARK 35 Saturday, September 13th, 2025 |
| Week 4 | Tulane vs Ole Miss | MISS 45, TULN 10 Saturday, September 20th, 2025 |
| Week 5 | LSU vs Ole Miss | MISS 24, LSU 19 Saturday, September 27th, 2025 |
| Week 7 | Washington State vs Ole Miss | MISS 24, WSU 21 Saturday, October 11th, 2025 |
| Week 8 | Ole Miss vs Georgia | UGA 43, MISS 35 Saturday, October 18th, 2025 |
| Week 9 | Ole Miss vs Oklahoma | Saturday, October 25th, 2025 12:00 pm EDT |
| Week 10 | South Carolina vs Ole Miss | Saturday, November 1st, 2025 12:00 am EDT |
| Week 11 | The Citadel vs Ole Miss | Saturday, November 8th, 2025 1:00 pm EST |
| Week 12 | Florida vs Ole Miss | Saturday, November 15th, 2025 12:00 am EST |
| Week 14 | Ole Miss vs Mississippi State | Friday, November 28th, 2025 12:00 pm EST |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the LSU vs Ole Miss College Football Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 27th, 2025 at 3:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Football page, look for the LSU vs Ole Miss Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the LSU vs Ole Miss Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 27, 2025 NCAAFB Games
- South Alabama vs North Texas
- Louisville vs Pittsburgh
- Duke vs Syracuse
- Georgia Tech vs Wake Forest
- New Haven vs Duquesne
- Norfolk State vs Wagner
- Bowling Green vs Ohio
- Stetson vs Dayton
- Penn vs Lehigh
- Rutgers vs Minnesota
- UCF vs Kansas State
- Cincinnati vs Kansas
- Georgetown vs Columbia
- Delaware State vs Sacred Heart
- Dartmouth vs Central Connecticut
- Notre Dame vs Arkansas
- Cornell vs Yale
- USC vs Illinois
- Utah State vs Vanderbilt
- Eastern Michigan vs Central Michigan
- Georgia Southern vs James Madison
- Howard vs Richmond
- South Dakota vs North Dakota State
- Utah Tech vs Austin Peay
- Hampton vs Elon
- Arkansas State vs Louisiana-Monroe
- Alabama State vs Florida A&M
- Idaho State vs Northern Colorado
- Mercyhurst vs South Dakota State
- Alabama A&M vs Bethune-Cookman
- Lindenwood vs Miami (OH)
- Merrimack College vs Stony Brook
- Furman vs Samford
- North Carolina A&T vs Maine
- Princeton vs Lafayette
- Western Carolina vs Campbell
- San Diego State vs Northern Illinois
- UConn vs Buffalo
- UCLA vs Northwestern
- Akron vs Toledo
- Baylor vs Oklahoma State
- California vs Boston College
- Rice vs Navy
- Utah vs West Virginia
- Ohio State vs Washington
- Indiana vs Iowa
- Auburn vs Texas A&M
- New Mexico State vs New Mexico
- Hawaii vs Air Force
- Tulane vs Tulsa
- Tennessee vs Mississippi State
- Mercer vs East Tennessee State
- The Citadel vs Chattanooga
- Nicholls vs Eastern Kentucky
- South Carolina State vs Charleston Southern
- St. Francis (PA) vs Bucknell
- Brown vs Harvard
- Middle Tennessee vs Kennesaw State
- Liberty vs Old Dominion
- Rhode Island vs Western Michigan
- Virginia Tech vs NC State
- UTRGV vs Southeastern Louisiana
- Alcorn State vs Arkansas-Pine Bluff
- Memphis vs Florida Atlantic
- Southeast Missouri State vs UT-Martin
- Abilene Christian vs Incarnate Word
- Central Arkansas vs Lamar
- Grambling State vs Prairie View A&M
- Jacksonville State vs Southern Miss
- North Carolina Central vs East Texas A&M
- Jackson State vs Southern
- Arizona vs Iowa State
- Western Kentucky vs Missouri State
- San Jose State vs Stanford
- UMass vs Missouri
- Alabama vs Georgia
- Oregon vs Penn State
- Appalachian State vs Boise State
- Washington State vs Colorado State
- Kentucky vs South Carolina
- McNeese State vs Stephen F. Austin
- Marshall vs Louisiana
- West Georgia vs Southern Utah
- Louisiana Tech vs UTEP
- Cal Poly vs Sacramento State
- Weber State vs UC Davis
- Idaho vs Montana
- BYU vs Colorado