Oakland Athletics vs Seattle Mariners Odds

The Athletics will play the Mariners on Wednesday, April 22nd, 2026. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Oakland Athletics have a 91.33 power ranking. The power ranking for the Seattle Mariners is 91.00.
  • Visiting Oakland Athletics - The Oakland Athletics have a 8-6 record as a visiting team, ranking them 2nd Overall for visiting team wins.
  • Home Seattle Mariners - The Seattle Mariners have a 9-7 record as a home team. They rank 1st for home team wins in the Overall standings.
  • Runs Scored - The Oakland Athletics currently stand 15th (102) Overall, with the Seattle Mariners ranking 17th (96) for runs scored.
  • Runs Allowed - The Oakland Athletics are 7th (116) Overall for runs allowed. The Seattle Mariners stand 16th (95) for runs allowed.
  • Team Streaks - The Oakland Athletics have won their last 2 games. Meanwhile, the Seattle Mariners have lost their last 2 games.
  • Team Records - The Oakland Athletics have a 13-11 Overall record (0.0 GB American West Division), with the Seattle Mariners possessing a 10-15 Overall standing (3.5 GB American West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arrr, me hearties! The Oakland Athletics be settin' sail fer a showdown in Seattle...

With a record like 13-11, they be lookin' to plunder the Mariners' home field...

Ye scallywags best be visitin' SportsBetting3.com to bet on this game, review the odds below...

The Mariners be strugglin' with a win percentage of just 0.400...

But don't let yer guard down, the A's last 10 games record be 6-4...

It be a battle on the high seas, me mateys, so set yer sights on victory!

Best Athletics at Mariners Odds


Best Moneyline Betting Odds
Underdog

Oakland Athletics
Favorite

Seattle Mariners
The Seattle Mariners are the -180 moneyline favorite. Risk $180 to win $100 on the Seattle Mariners at BetMGM. The Oakland Athletics are the +145 underdog at BetMGM. Risk $100 to win $145 on the Oakland Athletics. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7.5 runs. Risk $105 to win $100. BetMGM has the best under line of 7.5 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Oakland Athletics
Favorite

Seattle Mariners
The Seattle Mariners have a -1.5 +125 run line at BetMGM OH. They are the run line favorite in this matchup. The Oakland Athletics have a +1.5 -155 run line at BetMGM OH. The Oakland Athletics are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Oakland Athletics vs Seattle Mariners MLB game on Wednesday, April 22nd, 2026?

The Seattle Mariners are the -180 moneyline favorite at BetMGM and the Oakland Athletics are the +145 moneyline underdog at BetMGM.

What is the over-under total line for the Oakland Athletics vs Seattle Mariners MLB game on Wednesday, April 22nd, 2026?

The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Oakland Athletics vs Seattle Mariners MLB game on Wednesday, April 22nd, 2026?

The Seattle Mariners are -1.5 +125 run line favorites at BetMGM, while the Oakland Athletics are +1.5 -155 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Athletics
Mariners
4/22/26 4:10pm EDT
+145-180
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Oakland Athletics bettors risk $100 to win $145 at +145 odds. The implied probability for Oakland Athletics is 40.82%.
  • Seattle Mariners bettors risk $100 to win $55.56 at -180 odds. The implied probability for Seattle Mariners is 64.29%.

Oakland Athletics at Seattle Mariners Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Athletics
Mariners
First Team to Score
4/22/26 4:10pm EDT
-120-105Bet
Athletics
Mariners
Tie
1st Inning Winner
4/22/26 4:10pm EDT
+340+260-135Bet
Athletics
Mariners
Tie
First 3 Innings Winner
4/22/26 4:10pm EDT
+180+110+290Bet
Athletics
Mariners
To Extra Innings
4/22/26 4:10pm EDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Athletics
Mariners
1st Team to Score Will Win
4/22/26 4:10pm EDT
Yes -250No +190Bet
Mariners
Total Runs
OAK at SEA
4/22/26 4:10pm EDT
4.5 o +1154.5 u -150Bet

Oakland Athletics & Seattle Mariners Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Oakland Athletics World Series Odds
2026 Oakland Athletics World Series Odds

Team
BetMGM Sports Betting BetMGM
Athletics
+5500
Bet
Seattle Mariners World Series Odds
2026 Seattle Mariners World Series Odds

Team
BetMGM Sports Betting BetMGM
Mariners
+1300
Bet

Oakland Athletics & Seattle Mariners Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Oakland Athletics, Seattle Mariners
Team W L Pct GB Home Away RS RA Diff Strk L10
Oakland Athletics13110.542+3.55-58-6102116-14W26-4
Seattle Mariners10150.400+7.09-71-89695+1L24-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Oakland Athletics vs Seattle Mariners MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 22nd, 2026 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Oakland Athletics vs Seattle Mariners Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Oakland Athletics vs Seattle Mariners Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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