Indiana vs Ohio State Football Odds

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The Hoosiers will play the Buckeyes on Saturday, December 6th, 2025.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.


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Table of Contents

Best Hoosiers at Buckeyes Odds


Best Point Spread Betting Odds
Underdog

Indiana		Favorite

Ohio State
+4.5 -105 BetMGM
Bet
-4.5 -115 BetMGM
Bet
Ohio State has a -4.5 -115 point spread at BetMGM OH. They are the point spread favorite in this matchup. Indiana has a +4.5 -105 point spread at BetMGM OH. Indiana is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
48.5 o -102 BetMGM
Bet
48.5 u -118 BetMGM
Bet
BetMGM has the best over line of 48.5 points. Risk $102 to win $100. BetMGM has the best under line of 48.5 points. Risk $118 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Indiana		Favorite

Ohio State
+170 BetMGM
Bet
-210 BetMGM
Bet
Ohio State is the -210 moneyline favorite. Risk $210 to win $100 on Ohio State at BetMGM. Indiana is the +170 underdog at BetMGM. Risk $100 to win $170 on Indiana. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Indiana vs Ohio State College Football game on Saturday, December 6th, 2025?

Ohio State is a -4.5 -115 point spread favorite at BetMGM, while Indiana is a +4.5 -105 point spread underdog at BetMGM.

What is the over-under total line for the Indiana vs Ohio State College Football game on Saturday, December 6th, 2025?

The best over line is 48.5 -102 points at BetMGM, which means you risk $102 to win $100 betting the over. The best under line is 48.5 -118 points at BetMGM, and that means you risk $118 to win $100 betting the under.

What is the moneyline for the Indiana vs Ohio State College Football game on Saturday, December 6th, 2025?

Ohio State is a -210 moneyline favorite at BetMGM and Indiana is a +170 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained

Game		 BetMGM Sports Betting BetMGM
Bet
Indiana
Ohio State
12/06/25 8:00pm EST
+4.5 -105-4.5 -115
Bet $100 at BetMGM Ohio
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Gambling Problem? Call 1-800-589-9966

Underdog Indiana - Indiana bettors risk $100 to win $95.24 at -105 odds.

A +4.5 Indiana underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.

Favorite Ohio State - Ohio State bettors risk $100 to win $86.96 at -115 odds.

A -4.5 Ohio State favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.

Indiana at Ohio State Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Indiana
Ohio State
No Touchdown
To Score 1st Touchdown
12/06/25 8:00pm EST
+115-165+10000Bet
Indiana
Ohio State
Game to Overtime
12/06/25 8:00pm EST
Yes +1100No -10000Bet
Indiana
Ohio State
Both Teams Score 10+
12/06/25 8:00pm EST
Yes -750No +475Bet
Indiana
Ohio State
Both Teams Score 20+
12/06/25 8:00pm EST
Yes +105No -135Bet
BetMGM Sports Betting BetMGM
Indiana
Ohio State
Both Teams Score 30+
12/06/25 8:00pm EST
Yes +675No -1400Bet

Recent Meetings Since 2021

Recent Meetings Since 2021
WeekGameResultMargin
2024
Week 13		Indiana vs Ohio State
Saturday, November 23rd, 2024		OSU 38, IU 15
Ohio Stadium		Ohio State by 23
2023
Week 1		Ohio State vs Indiana
Saturday, September 2nd, 2023		OSU 23, IU 3
Memorial Stadium (Bloomington, IN)		Ohio State by 20
2022
Week 11		Indiana vs Ohio State
Saturday, November 12th, 2022		OSU 56, IU 14
Ohio Stadium		Ohio State by 42
2021
Week 8		Ohio State vs Indiana
Saturday, October 23rd, 2021		OSU 54, IU 7
Memorial Stadium (Bloomington, IN)		Ohio State by 47

Team Standings

2025-2026 College Football Regular Season Standings - Indiana, Ohio State
Team Conf Conf% W L PF PA Home Away Strk
#2 Indiana9-01.0001205321317-05-0W12
#1 Ohio State9-01.000120444937-05-0W12

Indiana & Ohio State Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Indiana Championship Odds
2025-26 Indiana NCAA College Football Championship Odds

Team
OH,US ncaafb Evnum: 1 Odds Pending
Ohio State Championship Odds
2025-26 Ohio State NCAA College Football Championship Odds

Team
OH,US ncaafb Evnum: 1 Odds Pending

Indiana & Ohio State Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results


2025-26 Indiana Games & Results
WeekMatchupDate & Result
Week 1Old Dominion vs
Indiana		IU 27, ODU 14
Saturday, August 30th, 2025
Week 2Kennesaw State vs
Indiana		IU 56, KENN 9
Saturday, September 6th, 2025
Week 3Indiana State vs
Indiana		IU 73, INST 0
Friday, September 12th, 2025
Week 4Illinois vs
Indiana		IU 63, ILL 10
Saturday, September 20th, 2025
Week 5Indiana vs
Iowa		IU 20, IOWA 15
Saturday, September 27th, 2025
Week 7Indiana vs
Oregon		IU 30, ORE 20
Saturday, October 11th, 2025
Week 8Michigan State vs
Indiana		IU 38, MSU 13
Saturday, October 18th, 2025
Week 9UCLA vs
Indiana		Saturday, October 25th, 2025
12:00 pm EDT
Week 10Indiana vs
Maryland		Saturday, November 1st, 2025
3:30 pm EDT
Week 11Indiana vs
Penn State		Saturday, November 8th, 2025
12:00 am EST
Week 12Wisconsin vs
Indiana		Saturday, November 15th, 2025
12:00 am EST
Week 14Indiana vs
Purdue		Friday, November 28th, 2025
7:30 pm EST


2025-26 Ohio State Games & Results
WeekMatchupDate & Result
Week 1Texas vs
Ohio State		OSU 14, TEX 7
Saturday, August 30th, 2025
Week 2Grambling State vs
Ohio State		OSU 70, GRAM 0
Saturday, September 6th, 2025
Week 3Ohio vs
Ohio State		OSU 37, OHIO 9
Saturday, September 13th, 2025
Week 5Ohio State vs
Washington		OSU 24, WASH 6
Saturday, September 27th, 2025
Week 6Minnesota vs
Ohio State		OSU 42, MINN 3
Saturday, October 4th, 2025
Week 7Ohio State vs
Illinois		OSU 34, ILL 16
Saturday, October 11th, 2025
Week 8Ohio State vs
Wisconsin		OSU 34, WIS 0
Saturday, October 18th, 2025
Week 10Penn State vs
Ohio State		Saturday, November 1st, 2025
12:00 am EDT
Week 11Ohio State vs
Purdue		Saturday, November 8th, 2025
12:00 am EST
Week 12UCLA vs
Ohio State		Saturday, November 15th, 2025
12:00 am EST
Week 13Rutgers vs
Ohio State		Saturday, November 22nd, 2025
12:00 am EST
Week 14Ohio State vs
Michigan		Saturday, November 29th, 2025
12:00 pm EST

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Indiana vs Ohio State College Football Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, December 6th, 2025 at 8:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Football page, look for the Indiana vs Ohio State Game.

    Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Indiana vs Ohio State Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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