Cincinnati Reds vs San Diego Padres Odds

The Reds will play the Padres on Wednesday, September 10th, 2025. Your timezone's first pitch time is 8:40 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

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Best Reds at Padres Odds

**Best Moneyline Betting Odds**
Underdog Cincinnati Reds	Favorite San Diego Padres
+125 BetMGM Bet	-150 BetMGM Bet

The San Diego Padres are the -150 moneyline favorite. Risk $150 to win $100 on the San Diego Padres at BetMGM. The Cincinnati Reds are the +125 underdog at BetMGM. Risk $100 to win $125 on the Cincinnati Reds. Learn more about how to bet on money lines.

**Best Total Betting Odds**
Over	Under
7.5 o -105 BetMGM Bet	7.5 u -115 BetMGM Bet

BetMGM has the best over line of 7.5 runs. Risk $105 to win $100. BetMGM has the best under line of 7.5 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

**Best Run Line Betting Odds**
Underdog Cincinnati Reds	Favorite San Diego Padres
+1.5 -190 BetMGM Bet	-1.5 +154 BetMGM Bet

The San Diego Padres have a -1.5 +154 run line at BetMGM OH. They are the run line favorite in this matchup. The Cincinnati Reds have a +1.5 -190 run line at BetMGM OH. The Cincinnati Reds are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Cincinnati Reds vs San Diego Padres MLB game on Wednesday, September 10th, 2025?

The San Diego Padres are the -150 moneyline favorite at BetMGM and the Cincinnati Reds are the +125 moneyline underdog at BetMGM.

What is the over-under total line for the Cincinnati Reds vs San Diego Padres MLB game on Wednesday, September 10th, 2025?

The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Cincinnati Reds vs San Diego Padres MLB game on Wednesday, September 10th, 2025?

The San Diego Padres are -1.5 +154 run line favorites at BetMGM, while the Cincinnati Reds are +1.5 -190 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	BetMGM Bet
Reds Padres 9/10/25 8:40pm EDT	+125 -150

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Possible Moneyline Outcomes

Cincinnati Reds bettors risk $100 to win $125 at +125 odds. The implied probability for Cincinnati Reds is 44.44%.
San Diego Padres bettors risk $100 to win $66.67 at -150 odds. The implied probability for San Diego Padres is 60%.

Cincinnati Reds at San Diego Padres Prop Bets

MLB Prop Bets
+ Displays more odds
	BetMGM Bet
Reds Padres First Team to Score 9/10/25 8:40pm EDT	-135 +105 Bet
Reds Padres Tie 1st Inning Winner 9/10/25 8:40pm EDT	+325 +300 -150 Bet
Reds Padres Tie First 3 Innings Winner 9/10/25 8:40pm EDT	+160 +130 +260 Bet
Reds Padres To Extra Innings 9/10/25 8:40pm EDT	Yes +725 No -1200 Bet
	BetMGM
Reds Padres 1st Team to Score Will Win 9/10/25 8:40pm EDT	Yes -250 No +190 Bet
Reds Total Runs CIN at SDG 9/10/25 8:40pm EDT	3.5 o -102 3.5 u -130 Bet
Padres Total Runs CIN at SDG 9/10/25 8:40pm EDT	3.5 o -140 3.5 u +105 Bet
Andrew Abbott Strikeouts Thrown CIN at SDG 9/10/25 8:40pm EDT	4.5 o +110 4.5 u -150 Bet
	BetMGM
Nick Pivetta Strikeouts Thrown CIN at SDG 9/10/25 8:40pm EDT	6.5 o -135 6.5 u +100 Bet

Cincinnati Reds & San Diego Padres Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cincinnati Reds World Series Odds

2026 Cincinnati Reds World Series Odds
Team	BetMGM
Reds	+3500 Bet

San Diego Padres World Series Odds

2026 San Diego Padres World Series Odds
Team	BetMGM
Padres	+2000 Bet

Cincinnati Reds & San Diego Padres Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Cincinnati Reds, San Diego Padres
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
y - San Diego Padres	90	72	0.556	+7.0	52-29	38-43	702	621	+81	W3	7-3
y - Cincinnati Reds	83	79	0.512	+14.0	45-36	38-43	716	681	+35	L1	7-3

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Cincinnati Reds vs San Diego Padres MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, September 10th, 2025 at 8:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the Cincinnati Reds vs San Diego Padres Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cincinnati Reds vs San Diego Padres Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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