The Cardinals will play the Mariners on Wednesday, September 10th, 2025. Your timezone's first pitch time is 9:40 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Cardinals at Mariners Odds
| Underdog St. Louis Cardinals | Favorite Seattle Mariners |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite Seattle Mariners |
|---|---|
Matchup Odds FAQs
The Seattle Mariners are the -225 moneyline favorite at BetMGM and the St. Louis Cardinals are the +185 moneyline underdog at BetMGM.
The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.
The Seattle Mariners are -1.5 -105 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -115 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cardinals
Mariners
9/10/25 9:40pm EDT | +185-225 |
- St. Louis Cardinals bettors risk $100 to win $185 at +185 odds. The implied probability for St. Louis Cardinals is 35.09%.
- Seattle Mariners bettors risk $100 to win $44.44 at -225 odds. The implied probability for Seattle Mariners is 69.23%.
St. Louis Cardinals at Seattle Mariners Prop Bets
| BetMGM Bet |
|
|---|---|
Cardinals
Mariners
First Team to Score
9/10/25 9:40pm EDT | -102-125Bet |
Cardinals
Mariners
Tie
1st Inning Winner
9/10/25 9:40pm EDT | +400+240-140Bet |
Cardinals
Mariners
Tie
First 3 Innings Winner
9/10/25 9:40pm EDT | +210-105+280Bet |
Cardinals
Mariners
To Extra Innings
9/10/25 9:40pm EDT | Yes +750No -1200Bet |
| BetMGM | |
Cardinals
Mariners
1st Team to Score Will Win
9/10/25 9:40pm EDT | Yes -250No +190Bet |
Mariners
Total Runs
STL at SEA 9/10/25 9:40pm EDT | 4.5 o +1004.5 u -130Bet |
Cardinals
Total Runs
STL at SEA 9/10/25 9:40pm EDT | 2.5 o -1452.5 u +110Bet |
Logan Gilbert
Strikeouts Thrown
STL at SEA 9/10/25 9:40pm EDT | 7.5 o +1157.5 u -155Bet |
| BetMGM | |
Michael McGreevy
Strikeouts Thrown
STL at SEA 9/10/25 9:40pm EDT | 3.5 o -1103.5 u -118Bet |
St. Louis Cardinals & Seattle Mariners Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
St. Louis Cardinals World Series Odds|
Team | BetMGM |
|---|---|
| Cardinals | +100000 Bet |
|
Team | BetMGM |
|---|---|
| Mariners | +1000 Bet |
St. Louis Cardinals & Seattle Mariners Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Seattle Mariners | 83 | 68 | 0.550 | +9.0 | 48-27 | 35-41 | 717 | 659 | +58 | W10 | 10-0 |
| St. Louis Cardinals | 74 | 79 | 0.484 | +19.0 | 42-36 | 32-43 | 653 | 711 | -58 | L1 | 3-7 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the St. Louis Cardinals vs Seattle Mariners MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, September 10th, 2025 at 9:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the St. Louis Cardinals vs Seattle Mariners Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the St. Louis Cardinals vs Seattle Mariners Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 10, 2025 MLB Games
- Milwaukee Brewers vs Texas Rangers - 9/10/25 2:35pm EDT
- Boston Red Sox vs Oakland Athletics - 9/10/25 3:35pm EDT
- Arizona Diamondbacks vs San Francisco Giants - 9/10/25 3:45pm EDT
- Minnesota Twins vs Los Angeles Angels - 9/10/25 4:07pm EDT
- Pittsburgh Pirates vs Baltimore Orioles - 9/10/25 6:35pm EDT
- Kansas City Royals vs Cleveland Guardians - 9/10/25 6:40pm EDT
- Washington Nationals vs Miami Marlins - 9/10/25 6:40pm EDT
- New York Mets vs Philadelphia Phillies - 9/10/25 6:45pm EDT
- Detroit Tigers vs New York Yankees - 9/10/25 7:05pm EDT
- Houston Astros vs Toronto Blue Jays - 9/10/25 7:07pm EDT
- Chicago Cubs vs Atlanta Braves - 9/10/25 7:15pm EDT
- Tampa Bay Rays vs Chicago White Sox - 9/10/25 7:40pm EDT
- Cincinnati Reds vs San Diego Padres - 9/10/25 8:40pm EDT
- Colorado Rockies vs Los Angeles Dodgers - 9/10/25 10:10pm EDT