The Twins will play the Guardians on Sunday, May 10th, 2026. Your timezone's first pitch time is 1:40 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Minnesota Twins have a 94.33 power ranking. The power ranking for the Cleveland Guardians is 93.00.
- Visiting Minnesota Twins - The Minnesota Twins have a 5-5 record as a visiting team, ranking them 5th Overall for visiting team wins.
- Home Cleveland Guardians - The Cleveland Guardians have a 8-4 record as a home team. They rank 2nd for home team wins in the Overall standings.
- Runs Scored - The Minnesota Twins currently stand 7th (117) Overall, with the Cleveland Guardians ranking 12th (105) for runs scored.
- Runs Allowed - The Minnesota Twins are 13th (103) Overall for runs allowed. The Cleveland Guardians stand 11th (109) for runs allowed.
- Team Streaks - The Minnesota Twins won their last game. Meanwhile, the Cleveland Guardians won their last game.
- Team Records - The Minnesota Twins have a 12-11 Overall record (1.0 GB American Central Division), with the Cleveland Guardians possessing a 14-11 Overall standing (0.0 GB American Central Division).
Best Twins at Guardians Odds
| Underdog Minnesota Twins | Favorite Cleveland Guardians |
|---|---|
| Over | Under |
|---|---|
| Underdog Minnesota Twins | Favorite Cleveland Guardians |
|---|---|
Matchup Odds FAQs
The Cleveland Guardians are the -165 moneyline favorite at BetMGM and the Minnesota Twins are the +140 moneyline underdog at BetMGM.
The best over line is 7.5 -102 runs at BetMGM, which means you risk $102 to win $100 betting the over. The best under line is 7.5 -118 runs at BetMGM, and that means you risk $118 to win $100 betting the under.
The Cleveland Guardians are -1.5 +140 run line favorites at BetMGM, while the Minnesota Twins are +1.5 -170 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Twins
Guardians
5/10/26 1:40pm EDT | +140-165 |
- Minnesota Twins bettors risk $100 to win $140 at +140 odds. The implied probability for Minnesota Twins is 41.67%.
- Cleveland Guardians bettors risk $100 to win $60.61 at -165 odds. The implied probability for Cleveland Guardians is 62.26%.
Minnesota Twins at Cleveland Guardians Prop Bets
| BetMGM Bet |
|
|---|---|
Twins
Guardians
First Team to Score
5/10/26 1:40pm EDT | -125-102Bet |
Twins
Guardians
Tie
1st Inning Winner
5/10/26 1:40pm EDT | +350+290-150Bet |
Twins
Guardians
Tie
First 3 Innings Winner
5/10/26 1:40pm EDT | +175+120+260Bet |
Twins
Guardians
To Extra Innings
5/10/26 1:40pm EDT | Yes +725No -1200Bet |
| BetMGM | |
Twins
Guardians
1st Team to Score Will Win
5/10/26 1:40pm EDT | Yes -250No +190Bet |
Guardians
Total Runs
MIN at CLE 5/10/26 1:40pm EDT | 3.5 o -1453.5 u +110Bet |
Twins
Total Runs
MIN at CLE 5/10/26 1:40pm EDT | 3.5 o +1053.5 u -140Bet |
Minnesota Twins & Cleveland Guardians Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Minnesota Twins World Series Odds|
Team | BetMGM |
|---|---|
| Twins | +15000 Bet |
|
Team | BetMGM |
|---|---|
| Guardians | +4500 Bet |
Minnesota Twins & Cleveland Guardians Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cleveland Guardians | 14 | 11 | 0.560 | +3.0 | 8-4 | 6-7 | 105 | 109 | -4 | W1 | 5-5 |
| Minnesota Twins | 12 | 11 | 0.522 | +4.0 | 7-6 | 5-5 | 117 | 103 | +14 | W1 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Minnesota Twins vs Cleveland Guardians MLB Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, May 10th, 2026 at 1:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's MLB page, look for the Minnesota Twins vs Cleveland Guardians Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Minnesota Twins vs Cleveland Guardians Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other May 10, 2026 MLB Games
- Washington Nationals vs Miami Marlins - 5/10/26 12:15pm EDT
- Oakland Athletics vs Baltimore Orioles - 5/10/26 1:35pm EDT
- Tampa Bay Rays vs Boston Red Sox - 5/10/26 1:35pm EDT
- Colorado Rockies vs Philadelphia Phillies - 5/10/26 1:35pm EDT
- Los Angeles Angels vs Toronto Blue Jays - 5/10/26 1:37pm EDT
- Houston Astros vs Cincinnati Reds - 5/10/26 1:40pm EDT
- Seattle Mariners vs Chicago White Sox - 5/10/26 2:10pm EDT
- New York Yankees vs Milwaukee Brewers - 5/10/26 2:10pm EDT
- Chicago Cubs vs Texas Rangers - 5/10/26 2:35pm EDT
- Pittsburgh Pirates vs San Francisco Giants - 5/10/26 4:05pm EDT
- New York Mets vs Arizona Diamondbacks - 5/10/26 4:10pm EDT
- Atlanta Braves vs Los Angeles Dodgers - 5/10/26 4:10pm EDT
- St. Louis Cardinals vs San Diego Padres - 5/10/26 4:10pm EDT
- Detroit Tigers vs Kansas City Royals - 5/10/26 7:20pm EDT