St. Louis Cardinals vs Washington Nationals MLB Betting Lines

Odds Preview 915

The Cardinals will play the Nationals on Wednesday, April 21st, 2021 at 4:05 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers

• Cardinals - C. Martinez - R
• Nationals - M. Scherzer - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

Best Money Line Bets

Underdog St. Louis Cardinals	Favorite Washington Nationals
+145 Sb3gen2	-170 Sb3gen2
+140 Sb3gen3	-170 Sb3gen3

Here are money lines for the outright winner. Favorite Washington Nationals has a minus value. Lay $170 at Sb3gen2 to win $100. Underdog St. Louis Cardinals has a positive value. Risk $100 at Sb3gen2 to win $145.

Best Over and Under Total Lines

Over	Under
7.5o +100 Sb3gen2	7.5u -110 Sb3gen3
7.5o -110 Sb3gen3	7.5u -120 Sb3gen2

The over under line estimates the combined total of each team's final score. Sb3gen2 has the best over line of 7.5 points laying $100 to win $100. Sb3gen3 has the best under line of 7.5 u -110.

Best Underdog and Favorite Run Line Bets

Underdog St. Louis Cardinals	Favorite Washington Nationals
+1.5 -140 Sb3gen2	-1.5 +120 Sb3gen2

SportsBetting3.com has analyzed the latest lines. Review our "Best Run Line Bets" table above to smash the books this Wednesday. Sb3gen2 has the best favorite Washington Nationals run line at -1.5 points. Sb3gen2 has the best underdog St. Louis Cardinals run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

St. Louis Cardinals World Series Odds

Outcome	SB3Gen

Cached 2021-12-01 17:08:41
Washington Nationals World Series Odds

Outcome	SB3Gen

Cached 2021-12-01 17:08:41

Team Standings

Season Standings

Team	W	L	Pct	GB	Home	Away	Strk	L10
St. Louis Cardinals	90	72	0.556	17.0	90-72	45-36	L2	79-63
Washington Nationals	65	97	0.401	42.0	65-97	35-46	L5	55-87

St. Louis Cardinals Batting Stats

2021 St. Louis Cardinals Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Tommy Edman 2B	160	91	168	11	56	38	95	0.262
Paul Goldschmidt 1B	158	102	177	31	99	67	136	0.294
Nolan Arenado 3B	157	81	151	34	105	50	96	0.255
Dylan Carlson RF	151	79	144	18	65	57	152	0.266
Tyler O'Neill LF	141	89	138	34	80	38	168	0.286
Matt Carpenter 2B	130	18	35	3	21	35	77	0.169
Yadier Molina C	121	45	111	11	66	24	79	0.252
Paul DeJong SS	114	44	70	19	45	35	103	0.197
Edmundo Sosa SS	113	39	78	6	27	17	63	0.271
Harrison Bader CF	103	45	98	16	50	27	85	0.267
Giovanny Gallegos RP	73	0	0	0	0	0	0	0.000
Genesis Cabrera RP	71	0	0	0	0	0	0	0.000

Washington Nationals Batting Stats

2021 Washington Nationals Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Juan Soto LF	151	111	157	29	95	145	93	0.313
Josh Bell 1B	144	75	130	27	88	65	101	0.261
Yadiel Hernandez LF	112	33	72	9	32	22	59	0.273
Ryan Zimmerman 1B	110	27	62	14	46	16	77	0.243
Andrew Stevenson CF	109	22	44	5	23	13	61	0.229
Victor Robles CF	107	37	64	2	19	33	85	0.203
Trea Turner 2B	96	66	125	18	49	26	77	0.322
Josh Harrison 2B	90	39	94	6	38	25	50	0.294
Starlin Castro 3B	87	25	89	3	38	26	62	0.283
Alcides Escobar SS	75	53	92	4	28	17	56	0.288
Kyle Schwarber 1B	72	42	67	25	53	31	88	0.253
Luis Garcia SS	70	29	57	6	22	11	43	0.242

St. Louis Cardinals Pitching Stats

2021 St. Louis Cardinals Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Adam Wainwright SP	32	17	7	0	0	206.1	174	1.06	3.05
Alex Reyes RP	70	10	8	29	3	72.1	95	1.35	3.24
Jack Flaherty SP	17	9	2	0	0	78.1	85	1.06	3.22
Kwang Hyun Kim SP	27	7	7	1	0	106.2	80	1.28	3.46
Giovanny Gallegos RP	73	6	5	14	24	80.1	95	0.88	3.02
Ryan Helsley RP	51	6	4	1	10	47.1	47	1.42	4.56
Matt Harvey SP	27	6	14	0	0	123.1	93	1.52	6.28
Tanner Scott RP	58	5	4	0	14	50.0	65	1.46	4.14
John Means SP	20	5	6	0	0	114.1	104	1.00	3.46
J.A. Happ SP	11	5	2	0	0	54.0	45	1.28	4.00
Genesis Cabrera RP	71	4	5	0	28	70.0	77	1.26	3.73
Paul Fry RP	52	4	5	2	11	47.1	60	1.52	6.08

Washington Nationals Pitching Stats

2021 Washington Nationals Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Patrick Corbin SP	31	9	16	0	0	171.2	143	1.47	5.82
Max Scherzer SP	19	8	4	0	0	111.0	147	0.89	2.76
Erick Fedde SP	29	7	9	0	0	133.1	128	1.44	5.47
Kyle Finnegan RP	68	5	9	11	13	66.0	68	1.48	3.55
Brad Hand RP	41	5	5	21	0	42.2	42	1.15	3.59
Paolo Espino RP	35	5	5	1	0	109.2	92	1.21	4.27
Joe Ross SP	20	5	9	0	0	108.0	109	1.22	4.17
Austin Voth SP	49	4	1	0	7	57.1	59	1.48	5.34
Daniel Hudson RP	31	4	1	0	14	32.2	48	0.92	2.20
Jon Lester SP	16	3	5	0	0	75.1	51	1.59	5.02
Wander Suero RP	45	2	3	0	7	42.2	44	1.41	6.33
Josiah Gray SP	12	2	2	0	0	62.2	63	1.34	5.31

More MLB Matchups

Matchup	Date & Time
San Francisco Giants vs Philadelphia Phillies	04/21/2021 1:05pm
Baltimore Orioles vs Miami Marlins	04/21/2021 1:10pm
Pittsburgh Pirates vs Detroit Tigers	04/21/2021 2:10pm
Houston Astros vs Colorado Rockies	04/21/2021 3:10pm
Minnesota Twins vs Oakland Athletics	04/21/2021 3:37pm
Texas Rangers vs Los Angeles Angels	04/21/2021 4:07pm
Milwaukee Brewers vs San Diego Padres	04/21/2021 4:10pm
Atlanta Braves vs New York Yankees	04/21/2021 6:35pm
Arizona Diamondbacks vs Cincinnati Reds	04/21/2021 6:40pm
Pittsburgh Pirates vs Detroit Tigers	04/21/2021 6:40pm
Toronto Blue Jays vs Boston Red Sox	04/21/2021 7:10pm
New York Mets vs Chicago Cubs	04/21/2021 7:40pm
Tampa Bay Rays vs Kansas City Royals	04/21/2021 8:10pm