The White Sox will play the Reds on Saturday, March 21st, 2026. Your timezone's first pitch time is 9:05 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best White Sox at Reds Odds
| Underdog Chicago White Sox | Favorite Cincinnati Reds |
|---|---|
| Over | Under |
|---|---|
| Underdog Chicago White Sox | Favorite Cincinnati Reds |
|---|---|
Matchup Odds FAQs
The Cincinnati Reds are the -135 moneyline favorite at BetMGM and the Chicago White Sox are the +110 moneyline underdog at BetMGM.
The best over line is 11.5 -120 runs at BetMGM, which means you risk $120 to win $100 betting the over. The best under line is 11.5 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The Cincinnati Reds are -1.5 +130 run line favorites at BetMGM, while the Chicago White Sox are +1.5 -155 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
White Sox
Reds
3/21/26 9:05pm EDT | +110-135 |
- Chicago White Sox bettors risk $100 to win $110 at +110 odds. The implied probability for Chicago White Sox is 47.62%.
- Cincinnati Reds bettors risk $100 to win $74.07 at -135 odds. The implied probability for Cincinnati Reds is 57.45%.
Chicago White Sox at Cincinnati Reds Prop Bets
| BetMGM Bet |
|
|---|---|
White Sox
Reds
3/21/26 9:05pm EDT | Pending BetMGM |
Chicago White Sox & Cincinnati Reds Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Chicago White Sox World Series Odds|
Team | BetMGM |
|---|---|
| White Sox | +40000 Bet |
|
Team | BetMGM |
|---|---|
| Reds | +5000 Bet |
Chicago White Sox & Cincinnati Reds Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Chicago White Sox | 0 | 1 | 0.000 | +1.5 | 0-0 | 0-1 | 2 | 14 | -12 | L1 | 0-1 |
| Cincinnati Reds | 0 | 1 | 0.000 | +1.5 | 0-1 | 0-0 | 0 | 3 | -3 | L1 | 0-1 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Chicago White Sox vs Cincinnati Reds MLB Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, March 21st, 2026 at 9:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's MLB page, look for the Chicago White Sox vs Cincinnati Reds Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago White Sox vs Cincinnati Reds Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other March 21, 2026 MLB Games
- Philadelphia Phillies vs Baltimore Orioles - 3/21/26 1:05pm EDT
- Atlanta Braves vs Boston Red Sox - 3/21/26 1:05pm EDT
- New York Yankees vs Detroit Tigers - 3/21/26 1:05pm EDT
- Toronto Blue Jays vs Pittsburgh Pirates - 3/21/26 1:05pm EDT
- Miami Marlins vs St. Louis Cardinals - 3/21/26 1:05pm EDT
- Minnesota Twins vs Tampa Bay Rays - 3/21/26 1:05pm EDT
- Oakland Athletics vs Los Angeles Dodgers - 3/21/26 2:05pm EDT
- Colorado Rockies vs Kansas City Royals - 3/21/26 3:05pm EDT
- Cleveland Guardians vs San Francisco Giants - 3/21/26 3:05pm EDT
- Texas Rangers vs Arizona Diamondbacks - 3/21/26 4:10pm EDT
- San Diego Padres vs Milwaukee Brewers - 3/21/26 4:10pm EDT
- Chicago Cubs vs Seattle Mariners - 3/21/26 9:10pm EDT