Cleveland Guardians vs San Francisco Giants Odds

The Guardians will play the Giants on Thursday, June 19th, 2025. Your timezone's first pitch time is 4:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the Cleveland Guardians possess a 90.00 SportsBetting3.com power ranking. The San Francisco Giants now have a 95.33 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting Cleveland Guardians - The Cleveland Guardians head into this matchup with a 15-15 record as a visiting team. This standing ranks them 3rd Overall for visiting team wins.
  • Home San Francisco Giants - The San Francisco Giants will throw the first pitch possessing a 17-9 home team record. That puts them 4th for home team wins in the Overall MLB standings.
  • Runs Scored - Cleveland Guardians batters have produced 216 runs, ranking them 19th Overall, with the San Francisco Giants ranking 10th (239) for runs scored.
  • Runs Allowed - Cleveland Guardians pitchers and fielders have allowed 236 runs, ranking them 11th Overall for runs allowed. Meanwhile, the San Francisco Giants now rank 22nd Overall, allowing 199 runs.
  • Team Streaks - The Cleveland Guardians have lost their last 3 games. Their opponent, the San Francisco Giants have lost their last 2 games.
  • Team Records - Let's review each team's records. The Cleveland Guardians have a 29-25 Overall record (6.0 GB American Central Division), with the San Francisco Giants notching a 31-24 Overall standing (3.0 GB National West Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arr, the Cleveland Guardians be facing the San Francisco Giants on Thursday...Ye Cleveland scallywags better be ready for a fierce battle on the diamond...The Giants, with a better win percentage, be no match for us...But beware, for they be a formidable opponent on their home turf...

Our Guardians need to plunder a victory from the Giants' grasp...Aye, we be needing to improve our win percentage and turn the tide...Don't be doubting our crew's abilities to come out victorious in this showdown...Prepare for a swashbuckling match that will have ye on the edge of yer seats...

This be a game not to be missed, me hearties...Place yer bets and watch as the Guardians take on the Giants...Check out this game's prop bets below and bet on MLB baseball at legal US sportsbooks...Review each team's standing at the bottom of the page to see who be on top...May the winds be at our backs as we sail into battle against the Giants!

Best Guardians at Giants Odds


Best Moneyline Betting Odds
Underdog

Cleveland Guardians
Favorite

San Francisco Giants
The San Francisco Giants are the -175 moneyline favorite. Risk $175 to win $100 on the San Francisco Giants at BetMGM. The Cleveland Guardians are the +145 underdog at BetMGM. Risk $100 to win $145 on the Cleveland Guardians. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7 runs. Risk $115 to win $100. BetMGM has the best under line of 7 runs. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cleveland Guardians
Favorite

San Francisco Giants
The San Francisco Giants have a -1.5 +135 run line at BetMGM OH. They are the run line favorite in this matchup. The Cleveland Guardians have a +1.5 -160 run line at BetMGM OH. The Cleveland Guardians are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Cleveland Guardians vs San Francisco Giants MLB game on Thursday, June 19th, 2025?

The San Francisco Giants are the -175 moneyline favorite at BetMGM and the Cleveland Guardians are the +145 moneyline underdog at BetMGM.

What is the over-under total line for the Cleveland Guardians vs San Francisco Giants MLB game on Thursday, June 19th, 2025?

The best over line is 7 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 7 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the run line for the Cleveland Guardians vs San Francisco Giants MLB game on Thursday, June 19th, 2025?

The San Francisco Giants are -1.5 +135 run line favorites at BetMGM, while the Cleveland Guardians are +1.5 -160 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Guardians
Giants
6/19/25 4:05pm EDT
+145-175
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Cleveland Guardians bettors risk $100 to win $145 at +145 odds. The implied probability for Cleveland Guardians is 40.82%.
  • San Francisco Giants bettors risk $100 to win $57.14 at -175 odds. The implied probability for San Francisco Giants is 63.64%.

Cleveland Guardians at San Francisco Giants Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Guardians
Giants
First Team to Score
6/19/25 4:05pm EDT
-110-118Bet
Guardians
Giants
To Extra Innings
6/19/25 4:05pm EDT
Yes +725No -1200Bet
Guardians
Giants
1st Team to Score Will Win
6/19/25 4:05pm EDT
Yes -250No +190Bet
Guardians
Total Runs
CLE at SFO
6/19/25 4:05pm EDT
2.5 o -1552.5 u +120Bet
BetMGM Sports Betting BetMGM
Giants
Total Runs
CLE at SFO
6/19/25 4:05pm EDT
3.5 o -1403.5 u +105Bet

Cleveland Guardians & San Francisco Giants Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cleveland Guardians World Series Odds
2025 Cleveland Guardians World Series Odds

Team
BetMGM Sports Betting BetMGM
Guardians
+10000
Bet
San Francisco Giants World Series Odds
2025 San Francisco Giants World Series Odds

Team
BetMGM Sports Betting BetMGM
Giants
+3300
Bet

Cleveland Guardians & San Francisco Giants Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Cleveland Guardians, San Francisco Giants
Team W L Pct GB Home Away RS RA Diff Strk L10
San Francisco Giants31240.564+4.517-914-15239199+40L25-5
Cleveland Guardians29250.537+6.014-1015-15216236-20L34-6

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Cleveland Guardians vs San Francisco Giants MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, June 19th, 2025 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs San Francisco Giants Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs San Francisco Giants Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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