Chicago White Sox vs Cleveland Indians MLB Betting Lines

Odds Preview 3043

The White Sox will play the Indians on Sunday, September 26th, 2021 at 1:10 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers

• White Sox - L. Giolito - R
• Indians - T. Mckenzie - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

Best Money Line Bets

Underdog Cleveland Indians	Favorite Chicago White Sox
+146 Sb3gen1	-158 Sb3gen1
+135 Sb3gen3	-160 Sb3gen2
+134 Sb3gen2	-160 Sb3gen3

Here are money lines for the outright winner. Favorite Chicago White Sox has a minus value. Lay $158 at Sb3gen1 to win $100. Underdog Cleveland Indians has a positive value. Risk $100 at Sb3gen1 to win $146.

Best Over and Under Total Lines

Over	Under
8o -125 Sb3gen1	8.5u -115 Sb3gen2
8.5o -105 Sb3gen2	8.5u -115 Sb3gen3
8.5o -105 Sb3gen3	8u +105 Sb3gen1

The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 8 points laying $125 to win $100. Sb3gen2 has the best under line of 8.5 u -115.

Best Underdog and Favorite Run Line Bets

Underdog Cleveland Indians	Favorite Chicago White Sox
+1.5 -115 Sb3gen3	-1.5 +100 Sb3gen2
+1.5 -118 Sb3gen1	-1.5 -102 Sb3gen1
+1.5 -120 Sb3gen2	-1.5 -105 Sb3gen3

SportsBetting3.com has analyzed the latest lines. Review our "Best Run Line Bets" table above to smash the books this Sunday. Sb3gen2 has the best favorite Chicago White Sox run line at -1.5 points. Sb3gen3 has the best underdog Cleveland Indians run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

Chicago White Sox World Series Odds

Outcome	SB3Gen
Chicago White Sox	+1600

Cached 2021-10-17 07:49:32
Cleveland Indians World Series Odds

Outcome	SB3Gen

Cached 2021-10-17 07:49:32

Team Standings

Season Standings

Team	W	L	Pct	GB	Home	Away	Strk	L10
Chicago White Sox	93	69	0.574	14.0	93-69	53-28	L1	79-63
Cleveland Indians	80	82	0.494	27.0	80-82	40-41	W1	71-71

Chicago White Sox Batting Stats

2021 Chicago White Sox Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Jose Abreu 1B	152	86	148	30	117	61	143	0.261
Yoan Moncada 3B	144	74	137	14	61	84	157	0.263
Andrew Vaughn RF	127	56	98	15	48	41	101	0.235
Leury Garcia LF	126	60	111	5	54	41	97	0.267
Tim Anderson SS	123	94	163	17	61	22	119	0.309
Bo Bichette SS	105	83	123	19	73	30	94	0.291
Marcus Semien SS	105	79	116	25	66	42	104	0.275
Jonathan Schoop 2B	105	59	117	18	62	27	90	0.285
Robbie Grossman LF	105	59	87	16	51	72	105	0.233
Vladimir Guerrero Jr. DH	104	82	123	34	85	59	75	0.322
Randal Grichuk CF	103	45	97	19	68	16	86	0.254
Jeimer Candelario 3B	100	47	102	7	36	48	94	0.274

Cleveland Indians Batting Stats

2021 Cleveland Indians Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Jose Ramirez 3B	152	111	147	36	103	72	87	0.266
Amed Rosario SS	141	77	155	11	57	31	120	0.282
Franmil Reyes RF	115	57	106	30	85	43	149	0.254
Bo Bichette SS	105	83	123	19	73	30	94	0.291
Marcus Semien SS	105	79	116	25	66	42	104	0.275
Vladimir Guerrero Jr. DH	104	82	123	34	85	59	75	0.322
Randal Grichuk CF	103	45	97	19	68	16	86	0.254
Harold Ramirez LF	99	33	91	7	41	14	56	0.268
Bradley Zimmer CF	99	44	68	8	35	30	122	0.227
Cesar Hernandez 2B	96	60	87	18	47	38	90	0.231
Lourdes Gurriel Jr. LF	93	39	89	11	42	17	73	0.264
Yu Chang SS	89	32	54	9	39	11	69	0.228

Chicago White Sox Pitching Stats

2021 Chicago White Sox Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Dylan Cease SP	32	13	7	0	0	165.2	226	1.25	3.91
Carlos Rodon SP	24	13	5	0	0	132.2	185	0.96	2.37
Lucas Giolito SP	31	11	9	0	0	178.2	201	1.10	3.53
Lance Lynn SP	28	11	6	0	0	157.0	176	1.07	2.69
Dallas Keuchel SP	32	9	9	0	0	162.0	95	1.53	5.28
Liam Hendriks RP	69	8	3	38	0	71.0	113	0.73	2.54
Aaron Bummer RP	62	5	5	2	21	56.1	75	1.26	3.51
Michael Kopech SP	44	4	3	0	15	69.1	103	1.13	3.50
Codi Dalton Heuer SP	40	4	1	0	14	38.2	39	1.42	5.12
Codi Heuer RP	40	4	1	0	14	38.2	39	1.42	5.12
Reynaldo Lopez SP	20	4	4	0	0	57.2	55	0.95	3.43
Garrett Crochet RP	54	3	5	0	14	54.1	65	1.27	2.82

Cleveland Indians Pitching Stats

2021 Cleveland Indians Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Aaron Civale SP	21	12	5	0	0	124.1	99	1.12	3.84
Zach Plesac SP	25	10	6	0	0	142.2	100	1.20	4.67
Lance Lynn SP	19	10	3	0	0	108.2	122	1.05	2.07
Cal Quantrill SP	40	8	3	0	1	149.2	121	1.18	2.89
Lucas Giolito SP	22	8	8	0	0	129.0	145	1.16	3.98
Dylan Cease SP	22	8	6	0	0	114.2	149	1.26	3.92
Carlos Rodon SP	18	8	5	0	0	104.2	149	0.96	2.49
James Karinchak RP	60	7	4	11	13	55.1	78	1.21	4.07
Dallas Keuchel SP	21	7	4	0	0	113.2	71	1.35	4.51
Shane Bieber SP	16	7	4	0	0	96.2	134	1.21	3.17
Bryan Shaw RP	81	6	7	2	20	77.1	71	1.38	3.49
Liam Hendriks RP	47	5	2	26	0	47.1	75	0.72	2.47

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