St. Louis Cardinals vs Chicago Cubs Odds

The Cardinals will play the Cubs on Sunday, July 6th, 2025. Your timezone's first pitch time is 6:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the St. Louis Cardinals possess a 95.33 SportsBetting3.com power ranking. The Chicago Cubs now have a 98.67 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting St. Louis Cardinals - The St. Louis Cardinals head into this matchup with a 11-16 record as a visiting team. This standing ranks them 7th Overall for visiting team wins.
  • Home Chicago Cubs - The Chicago Cubs will throw the first pitch possessing a 16-10 home team record. That puts them 5th for home team wins in the Overall MLB standings.
  • Runs Scored - St. Louis Cardinals batters have produced 256 runs, ranking them 8th Overall, with the Chicago Cubs ranking 1st (324) for runs scored.
  • Runs Allowed - St. Louis Cardinals pitchers and fielders have allowed 216 runs, ranking them 18th Overall for runs allowed. Meanwhile, the Chicago Cubs now rank 14th Overall, allowing 231 runs.
  • Team Streaks - The St. Louis Cardinals lost their last game. Their opponent, the Chicago Cubs have won their last 2 games.
  • Team Records - Let's review each team's records. The St. Louis Cardinals have a 30-24 Overall record (3.0 GB National Central Division), with the Chicago Cubs notching a 33-21 Overall standing (0.0 GB National Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye, mateys! The Cardinals be sailing into enemy territory on Sunday...to face the despicable Cubs in their own cursed den of iniquity...

With a record of 30-24, the Cardinals be needin' to plunder a victory...against the Cubs, who be boastin' a record of 33-21...

The Cubs be on a tear, winnin' 8 of their last 10...while the Cardinals be holdin' their own with a 6-4 record...

It be a battle of wits and skill on the diamond...bet on MLB baseball at legal US sportsbooks and see who emerges victorious...check out this game's prop bets below and may the best team prevail...

(These two teams be locked in a fierce rivalry...may the baseball gods favor the bold and grant us a thrilling match)...

Review each team's standing at the bottom of the page and place your bets wisely...may the wind be at the Cardinals' backs as they face their bitter foes...fare thee well, me hearties, and let the games begin!

Best Cardinals at Cubs Odds


Best Moneyline Betting Odds
Underdog

St. Louis Cardinals
Favorite

Chicago Cubs
The Chicago Cubs are the -220 moneyline favorite. Risk $220 to win $100 on the Chicago Cubs at BetMGM. The St. Louis Cardinals are the +180 underdog at BetMGM. Risk $100 to win $180 on the St. Louis Cardinals. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7.5 runs. Risk $100 to win $100. BetMGM has the best under line of 7.5 runs. Risk $120 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

St. Louis Cardinals
Favorite

Chicago Cubs
The Chicago Cubs have a -1.5 +100 run line at BetMGM OH. They are the run line favorite in this matchup. The St. Louis Cardinals have a +1.5 -120 run line at BetMGM OH. The St. Louis Cardinals are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the St. Louis Cardinals vs Chicago Cubs MLB game on Sunday, July 6th, 2025?

The Chicago Cubs are the -220 moneyline favorite at BetMGM and the St. Louis Cardinals are the +180 moneyline underdog at BetMGM.

What is the over-under total line for the St. Louis Cardinals vs Chicago Cubs MLB game on Sunday, July 6th, 2025?

The best over line is 7.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 7.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.

What is the run line for the St. Louis Cardinals vs Chicago Cubs MLB game on Sunday, July 6th, 2025?

The Chicago Cubs are -1.5 +100 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -120 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Cardinals
Cubs
7/06/25 6:10pm EDT
+180-220
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • St. Louis Cardinals bettors risk $100 to win $180 at +180 odds. The implied probability for St. Louis Cardinals is 35.71%.
  • Chicago Cubs bettors risk $100 to win $45.45 at -220 odds. The implied probability for Chicago Cubs is 68.75%.

St. Louis Cardinals at Chicago Cubs Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Cardinals
Cubs
First Team to Score
7/06/25 6:10pm EDT
+100-125Bet
Cardinals
Cubs
Tie
1st Inning Winner
7/06/25 6:10pm EDT
+400+260-150Bet
Cardinals
Cubs
Tie
First 3 Innings Winner
7/06/25 6:10pm EDT
+230+100+250Bet
Cardinals
Cubs
To Extra Innings
7/06/25 6:10pm EDT
Yes +750No -1200Bet
BetMGM Sports Betting BetMGM
Cardinals
Cubs
1st Team to Score Will Win
7/06/25 6:10pm EDT
Yes -250No +190Bet
Cubs
Total Runs
STL at CUB
7/06/25 6:10pm EDT
4.5 o +1054.5 u -140Bet
Cardinals
Total Runs
STL at CUB
7/06/25 6:10pm EDT
2.5 o -1402.5 u +105Bet
Erick Fedde
Strikeouts Thrown
STL at CUB
7/06/25 6:10pm EDT
3.5 o -1453.5 u +110Bet
BetMGM Sports Betting BetMGM
Matthew Boyd
Strikeouts Thrown
STL at CUB
7/06/25 6:10pm EDT
5.5 o +1255.5 u -160Bet

St. Louis Cardinals & Chicago Cubs Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

St. Louis Cardinals World Series Odds
2025 St. Louis Cardinals World Series Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+6000
Bet
Chicago Cubs World Series Odds
2025 Chicago Cubs World Series Odds

Team
BetMGM Sports Betting BetMGM
Cubs
+1300
Bet

St. Louis Cardinals & Chicago Cubs Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - St. Louis Cardinals, Chicago Cubs
Team W L Pct GB Home Away RS RA Diff Strk L10
Chicago Cubs33210.611+2.016-1017-11324231+93W28-2
St. Louis Cardinals30240.556+5.019-811-16256216+40L16-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the St. Louis Cardinals vs Chicago Cubs MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, July 6th, 2025 at 6:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the St. Louis Cardinals vs Chicago Cubs Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the St. Louis Cardinals vs Chicago Cubs Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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