The White Sox will play the Yankees on Thursday, September 25th, 2025. Your timezone's first pitch time is 7:05 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

STATE	Bonus

Best Odds
Interactive Odds Example
Prop Bets
Team Futures Odds
Team Pages
Team Standings
Other Games Today

Best White Sox at Yankees Odds

**Best Moneyline Betting Odds**
TBD	TBD

Moneyline odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

Total odds are updating, please check back soon.

**Best Run Line Betting Odds**
TBD	TBD

Run Line odds are updating, please check back soon.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	Book

Chicago White Sox at New York Yankees Prop Bets

MLB Prop Bets
+ Displays more odds
	Bet
White Sox Yankees 9/25/25 7:05pm EDT	Pending

Chicago White Sox & New York Yankees Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Chicago White Sox World Series Odds

No World Series TM Chicago White Sox YR: futures available

New York Yankees World Series Odds

No World Series TM New York Yankees YR: futures available

Chicago White Sox & New York Yankees Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Chicago White Sox, New York Yankees
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
y - New York Yankees	94	68	0.580	+3.0	50-31	44-37	849	685	+164	W8	9-1
e - Chicago White Sox	60	102	0.370	+37.0	33-48	27-54	647	742	-95	W1	3-7

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Chicago White Sox vs New York Yankees MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, September 25th, 2025 at 7:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the Chicago White Sox vs New York Yankees Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Chicago White Sox vs New York Yankees Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other September 25, 2025 MLB Games

Odds Preview 14390

Chicago White Sox vs New York Yankees Odds

Table of Contents