Pittsburgh Pirates vs Cincinnati Reds Odds

The Pirates will play the Reds on Thursday, September 25th, 2025. Your timezone's first pitch time is 2:00 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

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Best Pirates at Reds Odds

**Best Moneyline Betting Odds**
Underdog Pittsburgh Pirates	Favorite Cincinnati Reds
+140 BetMGM Bet	-170 BetMGM Bet

The Cincinnati Reds are the -170 moneyline favorite. Risk $170 to win $100 on the Cincinnati Reds at BetMGM. The Pittsburgh Pirates are the +140 underdog at BetMGM. Risk $100 to win $140 on the Pittsburgh Pirates. Learn more about how to bet on money lines.

**Best Total Betting Odds**
Over	Under
7.5 o -118 BetMGM Bet	7.5 u -102 BetMGM Bet

BetMGM has the best over line of 7.5 runs. Risk $118 to win $100. BetMGM has the best under line of 7.5 runs. Risk $102 to win $100. Our tutorial explains more about total bets.

**Best Run Line Betting Odds**
Underdog Pittsburgh Pirates	Favorite Cincinnati Reds
+1.5 -160 BetMGM Bet	-1.5 +135 BetMGM Bet

The Cincinnati Reds have a -1.5 +135 run line at BetMGM OH. They are the run line favorite in this matchup. The Pittsburgh Pirates have a +1.5 -160 run line at BetMGM OH. The Pittsburgh Pirates are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Pittsburgh Pirates vs Cincinnati Reds MLB game on Thursday, September 25th, 2025?

The Cincinnati Reds are the -170 moneyline favorite at BetMGM and the Pittsburgh Pirates are the +140 moneyline underdog at BetMGM.

What is the over-under total line for the Pittsburgh Pirates vs Cincinnati Reds MLB game on Thursday, September 25th, 2025?

The best over line is 7.5 -118 runs at BetMGM, which means you risk $118 to win $100 betting the over. The best under line is 7.5 -102 runs at BetMGM, and that means you risk $102 to win $100 betting the under.

What is the run line for the Pittsburgh Pirates vs Cincinnati Reds MLB game on Thursday, September 25th, 2025?

The Cincinnati Reds are -1.5 +135 run line favorites at BetMGM, while the Pittsburgh Pirates are +1.5 -160 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	BetMGM Bet
Pirates Reds 9/25/25 2:00pm EDT	+140 -170

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Possible Moneyline Outcomes

Pittsburgh Pirates bettors risk $100 to win $140 at +140 odds. The implied probability for Pittsburgh Pirates is 41.67%.
Cincinnati Reds bettors risk $100 to win $58.82 at -170 odds. The implied probability for Cincinnati Reds is 62.96%.

Pittsburgh Pirates at Cincinnati Reds Prop Bets

MLB Prop Bets
+ Displays more odds
	BetMGM Bet
Pirates Reds First Team to Score 9/25/25 2:00pm EDT	-118 -110 Bet
Pirates Reds Tie 1st Inning Winner 9/25/25 2:00pm EDT	+375 +280 -155 Bet
Pirates Reds Tie First 3 Innings Winner 9/25/25 2:00pm EDT	+195 +115 +250 Bet
Pirates Reds To Extra Innings 9/25/25 2:00pm EDT	Yes +725 No -1200 Bet
	BetMGM
Pirates Reds 1st Team to Score Will Win 9/25/25 2:00pm EDT	Yes -250 No +190 Bet
Reds Total Runs PIT at CIN 9/25/25 2:00pm EDT	4.5 o +115 4.5 u -150 Bet
Pirates Total Runs PIT at CIN 9/25/25 2:00pm EDT	3.5 o +100 3.5 u -130 Bet
Braxton Ashcraft Strikeouts Thrown PIT at CIN 9/25/25 2:00pm EDT	3.5 o -155 3.5 u +120 Bet
	BetMGM
Nick Lodolo Strikeouts Thrown PIT at CIN 9/25/25 2:00pm EDT	6.5 o +100 6.5 u -130 Bet

Pittsburgh Pirates & Cincinnati Reds Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Pittsburgh Pirates World Series Odds

No World Series TM Pittsburgh Pirates YR: futures available

Cincinnati Reds World Series Odds

No World Series TM Cincinnati Reds YR: futures available

Pittsburgh Pirates & Cincinnati Reds Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Pittsburgh Pirates, Cincinnati Reds
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
y - Cincinnati Reds	83	79	0.512	+14.0	45-36	38-43	716	681	+35	L1	7-3
e - Pittsburgh Pirates	71	91	0.438	+26.0	44-37	27-54	583	645	-62	L1	6-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Pittsburgh Pirates vs Cincinnati Reds MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Thursday, September 25th, 2025 at 2:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the Pittsburgh Pirates vs Cincinnati Reds Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Pittsburgh Pirates vs Cincinnati Reds Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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