Cincinnati Reds vs San Diego Padres Odds

The Reds will play the Padres on Wednesday, September 10th, 2025. Your timezone's first pitch time is 8:40 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Reds at Padres Odds


Best Moneyline Betting Odds
Underdog

Cincinnati Reds
Favorite

San Diego Padres
The San Diego Padres are the -150 moneyline favorite. Risk $150 to win $100 on the San Diego Padres at BetMGM. The Cincinnati Reds are the +125 underdog at BetMGM. Risk $100 to win $125 on the Cincinnati Reds. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7.5 runs. Risk $105 to win $100. BetMGM has the best under line of 7.5 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cincinnati Reds
Favorite

San Diego Padres
The San Diego Padres have a -1.5 +154 run line at BetMGM OH. They are the run line favorite in this matchup. The Cincinnati Reds have a +1.5 -190 run line at BetMGM OH. The Cincinnati Reds are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Cincinnati Reds vs San Diego Padres MLB game on Wednesday, September 10th, 2025?

The San Diego Padres are the -150 moneyline favorite at BetMGM and the Cincinnati Reds are the +125 moneyline underdog at BetMGM.

What is the over-under total line for the Cincinnati Reds vs San Diego Padres MLB game on Wednesday, September 10th, 2025?

The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the Cincinnati Reds vs San Diego Padres MLB game on Wednesday, September 10th, 2025?

The San Diego Padres are -1.5 +154 run line favorites at BetMGM, while the Cincinnati Reds are +1.5 -190 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Reds
Padres
9/10/25 8:40pm EDT
+125-150
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Cincinnati Reds bettors risk $100 to win $125 at +125 odds. The implied probability for Cincinnati Reds is 44.44%.
  • San Diego Padres bettors risk $100 to win $66.67 at -150 odds. The implied probability for San Diego Padres is 60%.

Cincinnati Reds at San Diego Padres Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Reds
Padres
First Team to Score
9/10/25 8:40pm EDT
-135+105Bet
Reds
Padres
Tie
1st Inning Winner
9/10/25 8:40pm EDT
+325+300-150Bet
Reds
Padres
Tie
First 3 Innings Winner
9/10/25 8:40pm EDT
+160+130+260Bet
Reds
Padres
To Extra Innings
9/10/25 8:40pm EDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Reds
Padres
1st Team to Score Will Win
9/10/25 8:40pm EDT
Yes -250No +190Bet
Reds
Total Runs
CIN at SDG
9/10/25 8:40pm EDT
3.5 o -1023.5 u -130Bet
Padres
Total Runs
CIN at SDG
9/10/25 8:40pm EDT
3.5 o -1403.5 u +105Bet
Andrew Abbott
Strikeouts Thrown
CIN at SDG
9/10/25 8:40pm EDT
4.5 o +1104.5 u -150Bet
BetMGM Sports Betting BetMGM
Nick Pivetta
Strikeouts Thrown
CIN at SDG
9/10/25 8:40pm EDT
6.5 o -1356.5 u +100Bet

Cincinnati Reds & San Diego Padres Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cincinnati Reds World Series Odds
2025 Cincinnati Reds World Series Odds

Team
BetMGM Sports Betting BetMGM
Reds
+20000
Bet
San Diego Padres World Series Odds
2025 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM
Padres
+1400
Bet

Cincinnati Reds & San Diego Padres Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Cincinnati Reds, San Diego Padres
Team W L Pct GB Home Away RS RA Diff Strk L10
San Diego Padres82690.543+10.047-2835-41644586+58L16-4
Cincinnati Reds76760.500+16.540-3436-42682656+26W15-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Cincinnati Reds vs San Diego Padres MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, September 10th, 2025 at 8:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Cincinnati Reds vs San Diego Padres Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cincinnati Reds vs San Diego Padres Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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