The Reds will play the Cardinals on Sunday, June 22nd, 2025. Your timezone's first pitch time is 2:15 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - As the 2025 season continues, the Cincinnati Reds possess a 93.67 SportsBetting3.com power ranking. The St. Louis Cardinals now have a 95.33 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
- Visiting Cincinnati Reds - The Cincinnati Reds head into this matchup with a 13-14 record as a visiting team. This standing ranks them 5th Overall for visiting team wins.
- Home St. Louis Cardinals - The St. Louis Cardinals will throw the first pitch possessing a 19-8 home team record. That puts them 2nd for home team wins in the Overall MLB standings.
- Runs Scored - Cincinnati Reds batters have produced 255 runs, ranking them 9th Overall, with the St. Louis Cardinals ranking 8th (256) for runs scored.
- Runs Allowed - Cincinnati Reds pitchers and fielders have allowed 227 runs, ranking them 15th Overall for runs allowed. Meanwhile, the St. Louis Cardinals now rank 18th Overall, allowing 216 runs.
- Team Streaks - The Cincinnati Reds won their last game. Their opponent, the St. Louis Cardinals lost their last game.
- Team Records - Let's review each team's records. The Cincinnati Reds have a 27-28 Overall record (6.5 GB National Central Division), with the St. Louis Cardinals notching a 30-24 Overall standing (3.0 GB National Central Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye, scallywags! The Reds be sailing to St. Louis on Sunday...to face the blasted Cardinals in a battle of the National League!
Cincinnati may be below .500, but they've been winning more lately...with a solid 6-4 record in their last 10 games. (Arrr, that be respectable!)
The Cardinals be holdin' a better record overall, but the Reds be hungry...for victory on enemy turf. (Let's show 'em what we're made of!)
So grab yer grog and set sail for a showdown on the diamond...as the Reds look to plunder a win from the Cardinals at home! (Check out this game's prop bets below, bet on MLB baseball at legal US sportsbooks, review each team's standing at the bottom of the page.)
Best Reds at Cardinals Odds
| Underdog St. Louis Cardinals | Favorite Cincinnati Reds |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite Cincinnati Reds |
|---|---|
Matchup Odds FAQs
The Cincinnati Reds are the -115 moneyline favorite at BetMGM and the St. Louis Cardinals are the -105 moneyline underdog at BetMGM.
The best over line is 9 -130 runs at BetMGM, which means you risk $130 to win $100 betting the over. The best under line is 9 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The Cincinnati Reds are -1.5 +140 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -170 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Reds
Cardinals
6/22/25 2:15pm EDT | -115-105 |
- St. Louis Cardinals bettors risk $100 to win $95.24 at -105 odds. The implied probability for St. Louis Cardinals is 51.22%.
- Cincinnati Reds bettors risk $100 to win $86.96 at -115 odds. The implied probability for Cincinnati Reds is 53.49%.
Cincinnati Reds at St. Louis Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Reds
Cardinals
First Team to Score
6/22/25 2:15pm EDT | -180+140Bet |
Reds
Cardinals
Tie
1st Inning Winner
6/22/25 2:15pm EDT | +250+320-125Bet |
Reds
Cardinals
Tie
First 3 Innings Winner
6/22/25 2:15pm EDT | +120+154+310Bet |
Reds
Cardinals
To Extra Innings
6/22/25 2:15pm EDT | Yes +800No -1400Bet |
| BetMGM | |
Reds
Cardinals
1st Team to Score Will Win
6/22/25 2:15pm EDT | Yes -250No +190Bet |
Reds
Total Runs
CIN at STL 6/22/25 2:15pm EDT | 4.5 o -1184.5 u -110Bet |
Cardinals
Total Runs
CIN at STL 6/22/25 2:15pm EDT | 4.5 o -1054.5 u -125Bet |
Andrew Abbott
Strikeouts Thrown
CIN at STL 6/22/25 2:15pm EDT | 4.5 o +1204.5 u -160Bet |
| BetMGM | |
Miles Mikolas
Strikeouts Thrown
CIN at STL 6/22/25 2:15pm EDT | 3.5 o -1103.5 u -115Bet |
Cincinnati Reds & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Cincinnati Reds World Series Odds|
Team | BetMGM |
|---|---|
| Reds | +10000 Bet |
|
Team | BetMGM |
|---|---|
| Cardinals | +6000 Bet |
Cincinnati Reds & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| St. Louis Cardinals | 30 | 24 | 0.556 | +5.0 | 19-8 | 11-16 | 256 | 216 | +40 | L1 | 6-4 |
| Cincinnati Reds | 27 | 28 | 0.491 | +8.5 | 14-14 | 13-14 | 255 | 227 | +28 | W1 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Cincinnati Reds vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, June 22nd, 2025 at 2:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Cincinnati Reds vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cincinnati Reds vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other June 22, 2025 MLB Games
- Baltimore Orioles vs New York Yankees - 6/22/25 11:35am EDT
- Detroit Tigers vs Tampa Bay Rays - 6/22/25 12:10pm EDT
- Texas Rangers vs Pittsburgh Pirates - 6/22/25 1:35pm EDT
- Chicago White Sox vs Toronto Blue Jays - 6/22/25 1:37pm EDT
- Atlanta Braves vs Miami Marlins - 6/22/25 1:40pm EDT
- Milwaukee Brewers vs Minnesota Twins - 6/22/25 2:10pm EDT
- Seattle Mariners vs Chicago Cubs - 6/22/25 2:20pm EDT
- Arizona Diamondbacks vs Colorado Rockies - 6/22/25 3:10pm EDT
- Boston Red Sox vs San Francisco Giants - 6/22/25 4:05pm EDT
- Cleveland Guardians vs Oakland Athletics - 6/22/25 4:05pm EDT
- Houston Astros vs Los Angeles Angels - 6/22/25 4:07pm EDT
- Washington Nationals vs Los Angeles Dodgers - 6/22/25 4:10pm EDT
- Kansas City Royals vs San Diego Padres - 6/22/25 4:10pm EDT
- New York Mets vs Philadelphia Phillies - 6/22/25 7:10pm EDT