Cincinnati Reds vs Tampa Bay Rays Odds

The Reds will play the Rays on Wednesday, April 22nd, 2026. Your timezone's first pitch time is 1:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Cincinnati Reds have a 96.33 power ranking. The power ranking for the Tampa Bay Rays is 89.00.
  • Visiting Cincinnati Reds - The Cincinnati Reds have a 10-2 record as a visiting team, ranking them 1st Overall for visiting team wins.
  • Home Tampa Bay Rays - The Tampa Bay Rays have a 4-4 record as a home team. They rank 6th for home team wins in the Overall standings.
  • Runs Scored - The Cincinnati Reds currently stand 17th (96) Overall, with the Tampa Bay Rays ranking 10th (110) for runs scored.
  • Runs Allowed - The Cincinnati Reds are 17th (93) Overall for runs allowed. The Tampa Bay Rays stand 3rd (127) for runs allowed.
  • Team Streaks - The Cincinnati Reds have won their last 5 games. Meanwhile, the Tampa Bay Rays have lost their last 3 games.
  • Team Records - The Cincinnati Reds have a 16-8 Overall record (0.0 GB National Central Division), with the Tampa Bay Rays possessing a 12-11 Overall standing (2.0 GB American East Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Arrr mateys! The Reds be sailin' into Tampa Bay with fire in their bellies...

16-8 record be no joke! They be crushin' all in their path...

But the Rays be no pushovers, with a decent 12-11 record... (Ye can bet on this game at SportsBetting3.com and review the odds below!)

The Reds be lookin' to keep their win streak alive against the Rays...

Will they plunder another victory or will the Rays send 'em packin'? Only time will tell...

Set sail for an epic battle on the diamond, me hearties! May the best team win!

Best Reds at Rays Odds


Best Moneyline Betting Odds
Underdog

Cincinnati Reds
Favorite

Tampa Bay Rays
The Tampa Bay Rays are the -135 moneyline favorite. Risk $135 to win $100 on the Tampa Bay Rays at BetMGM. The Cincinnati Reds are the +110 underdog at BetMGM. Risk $100 to win $110 on the Cincinnati Reds. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 8.5 runs. Risk $110 to win $100. BetMGM has the best under line of 8.5 runs. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cincinnati Reds
Favorite

Tampa Bay Rays
The Tampa Bay Rays have a -1.5 +154 run line at BetMGM OH. They are the run line favorite in this matchup. The Cincinnati Reds have a +1.5 -190 run line at BetMGM OH. The Cincinnati Reds are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Cincinnati Reds vs Tampa Bay Rays MLB game on Wednesday, April 22nd, 2026?

The Tampa Bay Rays are the -135 moneyline favorite at BetMGM and the Cincinnati Reds are the +110 moneyline underdog at BetMGM.

What is the over-under total line for the Cincinnati Reds vs Tampa Bay Rays MLB game on Wednesday, April 22nd, 2026?

The best over line is 8.5 -110 runs at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 8.5 -110 runs at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the run line for the Cincinnati Reds vs Tampa Bay Rays MLB game on Wednesday, April 22nd, 2026?

The Tampa Bay Rays are -1.5 +154 run line favorites at BetMGM, while the Cincinnati Reds are +1.5 -190 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Reds
Rays
4/22/26 1:10pm EDT
+110-135
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Cincinnati Reds bettors risk $100 to win $110 at +110 odds. The implied probability for Cincinnati Reds is 47.62%.
  • Tampa Bay Rays bettors risk $100 to win $74.07 at -135 odds. The implied probability for Tampa Bay Rays is 57.45%.

Cincinnati Reds at Tampa Bay Rays Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Reds
Rays
First Team to Score
4/22/26 1:10pm EDT
-145+110Bet
Reds
Rays
Tie
1st Inning Winner
4/22/26 1:10pm EDT
+310+270-130Bet
Reds
Rays
Tie
First 3 Innings Winner
4/22/26 1:10pm EDT
+154+120+300Bet
Reds
Rays
To Extra Innings
4/22/26 1:10pm EDT
Yes +750No -1200Bet
BetMGM Sports Betting BetMGM
Reds
Rays
1st Team to Score Will Win
4/22/26 1:10pm EDT
Yes -250No +190Bet
Reds
Total Runs
CIN at TAM
4/22/26 1:10pm EDT
3.5 o -1403.5 u +105Bet
Rays
Total Runs
CIN at TAM
4/22/26 1:10pm EDT
4.5 o +1054.5 u -140Bet

Cincinnati Reds & Tampa Bay Rays Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cincinnati Reds World Series Odds
2026 Cincinnati Reds World Series Odds

Team
BetMGM Sports Betting BetMGM
Reds
+8000
Bet
Tampa Bay Rays World Series Odds
2026 Tampa Bay Rays World Series Odds

Team
BetMGM Sports Betting BetMGM
Rays
+3500
Bet

Cincinnati Reds & Tampa Bay Rays Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Cincinnati Reds, Tampa Bay Rays
Team W L Pct GB Home Away RS RA Diff Strk L10
Cincinnati Reds1680.667+0.56-610-29693+3W58-2
Tampa Bay Rays12110.522+4.04-48-7110127-17L36-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Cincinnati Reds vs Tampa Bay Rays MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 22nd, 2026 at 1:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Cincinnati Reds vs Tampa Bay Rays Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cincinnati Reds vs Tampa Bay Rays Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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