Cleveland Indians vs Houston Astros MLB Betting Lines

Odds Preview 2123

The Indians will play the Astros on Wednesday, July 21st, 2021 at 8:10 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers
  • Indians - E. Morgan - R
  • Astros - L. Mccullers Jr - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

Best Money Line Bets
Underdog

Cleveland Indians
Favorite

Houston Astros
+220 Sb3gen1 -235 Sb3gen3
+220 Sb3gen2 -245 Sb3gen1
+190 Sb3gen3 -260 Sb3gen2
Here are money lines for the outright winner. Favorite Houston Astros has a minus value. Lay $235 at Sb3gen3 to win $100. Underdog Cleveland Indians has a positive value. Risk $100 at Sb3gen1 to win $220.
Best Over and Under Total Lines
OverUnder
8.5o -105 Sb3gen1 8.5u -105 Sb3gen3
8.5o -105 Sb3gen2 8.5u -115 Sb3gen1
8.5o -115 Sb3gen3 8.5u -115 Sb3gen2
The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 8.5 points laying $105 to win $100. Sb3gen3 has the best under line of 8.5 u -105.
Best Underdog and Favorite Run Line Bets
Underdog

Cleveland Indians
Favorite

Houston Astros
+1.5 +115 Sb3gen2 -1.5 -125 Sb3gen3
+1.5 +113 Sb3gen1 -1.5 -133 Sb3gen1
+1.5 +105 Sb3gen3 -1.5 -135 Sb3gen2
SportsBetting3.com has analyzed the latest lines. Review our "Best Run Line Bets" table above to smash the books this Wednesday. Sb3gen3 has the best favorite Houston Astros run line at -1.5 points. Sb3gen2 has the best underdog Cleveland Indians run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cleveland Indians World Series Odds
OutcomeSB3Gen SB3Gen

Cached 2021-12-06 04:16:37
Houston Astros World Series Odds
OutcomeSB3Gen SB3Gen
Houston Astros

Cached 2021-12-06 04:16:37

Team Standings

Season Standings
Team W L Pct GB Home Away Strk L10
Cleveland Indians
80 82 0.494 27.0 80-82 40-41 W1 71-71
Houston Astros
95 67 0.586 12.0 95-67 51-30 W2 86-56

Cleveland Indians Batting Stats

2021 Cleveland Indians Batting
Top 12 by Games Played
Player GP R H HR RBI BB SO AVG
Jose Ramirez
3B
152 111 147 36 103 72 87 0.266
Amed Rosario
SS
141 77 155 11 57 31 120 0.282
Franmil Reyes
RF
115 57 106 30 85 43 149 0.254
Bo Bichette
SS
105 83 123 19 73 30 94 0.291
Marcus Semien
SS
105 79 116 25 66 42 104 0.275
Vladimir Guerrero Jr.
DH
104 82 123 34 85 59 75 0.322
Randal Grichuk
CF
103 45 97 19 68 16 86 0.254
Harold Ramirez
LF
99 33 91 7 41 14 56 0.268
Bradley Zimmer
CF
99 44 68 8 35 30 122 0.227
Cesar Hernandez
2B
96 60 87 18 47 38 90 0.231
Lourdes Gurriel Jr.
LF
93 39 89 11 42 17 73 0.264
Yu Chang
SS
89 32 54 9 39 11 69 0.228

Houston Astros Batting Stats

2021 Houston Astros Batting
Top 12 by Games Played
Player GP R H HR RBI BB SO AVG
Carlos Correa
SS
148 104 155 26 92 75 116 0.279
Jose Altuve
2B
146 117 167 31 83 66 91 0.277
Yordan Alvarez
LF
144 92 149 33 104 50 145 0.277
Yuli Gurriel
1B
143 83 169 15 81 59 68 0.319
Kyle Tucker
CF
140 83 149 30 92 53 90 0.294
Martin Maldonado
C
125 40 64 12 36 47 127 0.172
Michael Brantley
RF
121 68 146 8 47 33 53 0.311
Chas McCormick
CF
108 47 73 14 50 25 104 0.257
Myles Straw
CF
98 44 85 2 34 38 71 0.262
Alex Bregman
3B
91 54 94 12 55 44 53 0.270
Aledmys Diaz
2B
84 28 76 8 45 16 62 0.259
Ryne Stanek
RP
72 0 0 0 0 0 0 0.000

Cleveland Indians Pitching Stats

2021 Cleveland Indians Pitching
Top 12 by Wins and Games Played
Player GP W L SV HLD IP K WHIP ERA
Aaron Civale
SP
21 12 5 0 0 124.1 99 1.12 3.84
Zach Plesac
SP
25 10 6 0 0 142.2 100 1.20 4.67
Lance Lynn
SP
19 10 3 0 0 108.2 122 1.05 2.07
Cal Quantrill
SP
40 8 3 0 1 149.2 121 1.18 2.89
Lucas Giolito
SP
22 8 8 0 0 129.0 145 1.16 3.98
Dylan Cease
SP
22 8 6 0 0 114.2 149 1.26 3.92
Carlos Rodon
SP
18 8 5 0 0 104.2 149 0.96 2.49
James Karinchak
RP
60 7 4 11 13 55.1 78 1.21 4.07
Dallas Keuchel
SP
21 7 4 0 0 113.2 71 1.35 4.51
Shane Bieber
SP
16 7 4 0 0 96.2 134 1.21 3.17
Bryan Shaw
RP
81 6 7 2 20 77.1 71 1.38 3.49
Liam Hendriks
RP
47 5 2 26 0 47.1 75 0.72 2.47

Houston Astros Pitching Stats

2021 Houston Astros Pitching
Top 12 by Wins and Games Played
Player GP W L SV HLD IP K WHIP ERA
Lance McCullers Jr.
SP
28 13 5 0 0 162.1 185 1.22 3.16
Zack Greinke
SP
30 11 6 0 1 171.0 120 1.17 4.16
Luis Garcia
SP
30 11 8 0 0 155.1 167 1.17 3.30
Framber Valdez
SP
22 11 6 0 0 134.2 125 1.25 3.14
Jose Urquidy
SP
20 8 3 0 0 107.0 90 0.99 3.62
Jake Odorizzi
SP
24 6 7 0 0 104.2 91 1.25 4.21
Ryan Pressly
RP
64 5 3 26 1 64.0 81 0.97 2.25
Blake Taylor
SP
51 4 4 0 5 42.2 41 1.41 3.16
Cristian Javier
RP
36 4 1 2 5 101.1 130 1.18 3.55
Phil Maton
RP
27 4 0 0 2 25.1 24 1.58 4.97
Ryne Stanek
RP
72 3 5 2 21 68.1 83 1.21 3.42
Bryan Abreu
SP
31 3 3 1 7 36.0 36 1.47 5.75

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