Cleveland Indians vs Houston Astros MLB Betting Lines

Odds Preview 2123

The Indians will play the Astros on Wednesday, July 21st, 2021 at 8:10 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers

Indians - E. Morgan - R
Astros - L. Mccullers Jr - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

**Best Money Line Bets**
Underdog Cleveland Indians	Favorite Houston Astros
+220 Sb3gen1	-235 Sb3gen3
+220 Sb3gen2	-245 Sb3gen1
+190 Sb3gen3	-260 Sb3gen2

Here are money lines for the outright winner. Favorite Houston Astros has a minus value. Lay $235 at Sb3gen3 to win $100. Underdog Cleveland Indians has a positive value. Risk $100 at Sb3gen1 to win $220.

**Best Over and Under Total Lines**
Over	Under
8.5o -105 Sb3gen1	8.5u -105 Sb3gen3
8.5o -105 Sb3gen2	8.5u -115 Sb3gen1
8.5o -115 Sb3gen3	8.5u -115 Sb3gen2

The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 8.5 points laying $105 to win $100. Sb3gen3 has the best under line of 8.5 u -105.

**Best Underdog and Favorite Run Line Bets**
Underdog Cleveland Indians	Favorite Houston Astros
+1.5 +115 Sb3gen2	-1.5 -125 Sb3gen3
+1.5 +113 Sb3gen1	-1.5 -133 Sb3gen1
+1.5 +105 Sb3gen3	-1.5 -135 Sb3gen2

SportsBetting3.com has analyzed the latest lines. Review our "Best Run Line Bets" table above to smash the books this Wednesday. Sb3gen3 has the best favorite Houston Astros run line at -1.5 points. Sb3gen2 has the best underdog Cleveland Indians run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

Cleveland Indians World Series Odds

Outcome	SB3Gen
Cleveland Indians	+6600

Cached 2021-07-26 21:15:00
Houston Astros World Series Odds

Outcome	SB3Gen
Houston Astros	+450

Cached 2021-07-26 21:15:00

Team Standings

**Season Standings**
Team	W	L	Pct	GB	Home	Away	Strk	L10
Cleveland Indians	48	47	0.505	12.0	24-21	24-26	L2	5-5
Houston Astros	59	39	0.602	2.5	32-20	27-19	W1	5-5

Cleveland Indians Batting Stats

**2021 Cleveland Indians Batting**
Top 12 by Games Played
Player	GP	R	H	HR	RBI	BB	SO	AVG
Cesar Hernandez 2B	91	55	81	16	43	36	89	0.226
Jose Ramirez 3B	87	63	78	19	52	38	47	0.252
Amed Rosario SS	87	42	85	5	27	19	72	0.262
Eddie Rosario LF	78	29	72	7	46	17	47	0.254
Josh Naylor LF	69	28	59	7	21	14	45	0.253
Harold Ramirez LF	62	25	57	6	24	10	32	0.279
Franmil Reyes RF	54	30	53	17	45	15	70	0.264
Yu Chang SS	50	13	20	2	14	5	33	0.179
Austin Hedges C	47	12	23	4	14	8	51	0.159
James Karinchak RP	44	0	0	0	0	0	0	0.000
Jake Bauers 1B	43	7	19	2	6	12	27	0.190
Bryan Shaw RP	43	0	0	0	0	0	0	0.000

Houston Astros Batting Stats

**2021 Houston Astros Batting**
Top 12 by Games Played
Player	GP	R	H	HR	RBI	BB	SO	AVG
Myles Straw CF	93	41	81	2	31	38	66	0.263
Yuli Gurriel 1B	91	47	104	10	59	38	40	0.313
Carlos Correa SS	89	63	89	16	53	48	75	0.269
Kyle Tucker LF	86	52	88	18	57	27	57	0.276
Jose Altuve 2B	85	72	96	23	59	44	61	0.277
Yordan Alvarez DH	82	55	87	17	61	25	95	0.282
Michael Brantley LF	76	48	101	6	35	19	35	0.330
Martin Maldonado C	70	25	39	6	23	24	80	0.172
Alex Bregman 3B	59	37	63	7	34	29	42	0.275
Chas McCormick RF	59	30	36	10	35	13	54	0.245
Ryne Stanek RP	40	0	0	0	0	0	0	0.000
Robel Garcia 2B	39	7	16	1	8	7	37	0.176

Cleveland Indians Pitching Stats

**2021 Cleveland Indians Pitching**
Top 12 by Wins and Games Played
Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Aaron Civale SP	15	10	2	0	0	97.2	76	1.06	3.32
Shane Bieber SP	14	7	4	0	0	90.2	130	1.25	3.28
James Karinchak RP	45	6	2	11	9	43.1	69	1.06	2.91
Zach Plesac SP	13	5	3	0	0	75.1	48	1.06	4.30
Bryan Shaw RP	44	3	4	2	14	43.1	53	1.34	2.91
Emmanuel Clase RP	42	3	5	11	6	40.0	43	1.25	2.03
Phil Maton RP	36	2	0	0	3	39.2	59	1.29	4.54
Nick Wittgren RP	34	2	3	1	8	33.0	37	1.21	5.73
Cal Quantrill SP	28	2	2	0	1	72.2	50	1.35	3.84
Nick Sandlin RP	26	1	0	0	4	27.1	39	1.17	2.63
Trevor Stephan RP	24	1	0	0	1	34.0	42	1.50	4.24
Blake Parker RP	17	1	0	0	1	15.2	11	1.28	2.87

Houston Astros Pitching Stats

**2021 Houston Astros Pitching**
Top 12 by Wins and Games Played
Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Zack Greinke SP	20	9	3	0	0	120.2	89	1.12	3.58
Luis Garcia SP	18	7	5	0	0	91.1	105	1.06	2.86
Lance McCullers Jr. SP	16	7	2	0	0	91.2	107	1.20	3.04
Jose Urquidy SP	14	6	3	0	0	77.1	66	0.96	3.38
Framber Valdez SP	10	5	2	0	0	60.2	56	1.32	3.26
Ryan Pressly RP	38	4	1	17	1	40.0	50	0.78	1.35
Bryan Abreu SP	27	3	3	1	5	32.0	30	1.34	4.22
Brandon Bielak RP	22	3	3	0	2	36.2	31	1.34	5.40
Cristian Javier RP	21	3	1	1	4	74.2	93	1.06	2.89
Jake Odorizzi SP	13	3	5	0	0	55.1	51	1.14	4.23
Brooks Raley RP	36	2	3	2	8	30.1	40	1.35	5.93
Blake Taylor SP	26	2	2	0	3	23.0	24	1.52	3.52

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