Houston Astros vs Cincinnati Reds Odds

The Astros will play the Reds on Sunday, May 10th, 2026. Your timezone's first pitch time is 1:40 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Houston Astros have a 88.00 power ranking. The power ranking for the Cincinnati Reds is 96.33.
  • Visiting Houston Astros - The Houston Astros have a 2-10 record as a visiting team, ranking them 8th Overall for visiting team wins.
  • Home Cincinnati Reds - The Cincinnati Reds have a 6-6 record as a home team. They rank 4th for home team wins in the Overall standings.
  • Runs Scored - The Houston Astros currently stand 2nd (135) Overall, with the Cincinnati Reds ranking 17th (96) for runs scored.
  • Runs Allowed - The Houston Astros are 1st (150) Overall for runs allowed. The Cincinnati Reds stand 17th (93) for runs allowed.
  • Team Streaks - The Houston Astros lost their last game. Meanwhile, the Cincinnati Reds have won their last 5 games.
  • Team Records - The Houston Astros have a 9-16 Overall record (4.5 GB American West Division), with the Cincinnati Reds possessing a 16-8 Overall standing (0.0 GB National Central Division).

Best Astros at Reds Odds


Best Moneyline Betting Odds
Underdog

Houston Astros
Favorite

Cincinnati Reds
The Cincinnati Reds are the -115 moneyline favorite. Risk $115 to win $100 on the Cincinnati Reds at BetRivers. The Houston Astros are the -108 underdog at BetRivers. Risk $108 to win $100 on the Houston Astros. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 9 runs. Risk $114 to win $100. BetRivers has the best under line of 9 runs. Risk $108 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Cincinnati Reds
Favorite

Houston Astros
The Houston Astros have a -1.5 +160 run line at BetRivers PA. They are the run line favorite in this matchup. The Cincinnati Reds have a +1.5 -200 run line at BetRivers PA. The Cincinnati Reds are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Houston Astros vs Cincinnati Reds MLB game on Sunday, May 10th, 2026?

The Cincinnati Reds are the -115 moneyline favorite at BetRivers and the Houston Astros are the -108 moneyline underdog at BetRivers.

What is the over-under total line for the Houston Astros vs Cincinnati Reds MLB game on Sunday, May 10th, 2026?

The best over line is 9 -114 runs at BetRivers, which means you risk $114 to win $100 betting the over. The best under line is 9 -108 runs at BetRivers, and that means you risk $108 to win $100 betting the under.

What is the run line for the Houston Astros vs Cincinnati Reds MLB game on Sunday, May 10th, 2026?

The Houston Astros are -1.5 +160 run line favorites at BetRivers, while the Cincinnati Reds are +1.5 -200 run line underdogs at BetRivers.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetRivers Sports Betting BetRivers
Bet
Astros
Reds
5/10/26 1:40pm EDT
-108-115
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Possible Moneyline Outcomes
  • Houston Astros bettors risk $100 to win $92.59 at -108 odds. The implied probability for Houston Astros is 51.92%.
  • Cincinnati Reds bettors risk $100 to win $86.96 at -115 odds. The implied probability for Cincinnati Reds is 53.49%.

Houston Astros at Cincinnati Reds Prop Bets

MLB Prop Bets
+ Displays more odds
BetRivers Sports Betting BetRivers
Bet
Astros
Reds
Tie
1st Inning Winner
5/10/26 1:40pm EDT
+260+280-118Bet
Astros
Reds
Tie
First 3 Innings Winner
5/10/26 1:40pm EDT
+135+138+300Bet
Reds
Total Runs
HOU at CIN
5/10/26 1:40pm EDT
4.5 o -1054.5 u -122Bet
Astros
Total Runs
HOU at CIN
5/10/26 1:40pm EDT
4.5 o -1044.5 u -124Bet
BetRivers Sports Betting BetRivers
Andrew Abbott
Strikeouts Thrown
HOU at CIN
5/10/26 1:40pm EDT
4.5 o +1104.5 u -148Bet

Houston Astros & Cincinnati Reds Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Houston Astros World Series Odds
2026 Houston Astros World Series Odds

Team
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Astros
+2000
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Cincinnati Reds World Series Odds
2026 Cincinnati Reds World Series Odds

Team
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Reds
+50000
Bet

Houston Astros & Cincinnati Reds Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Houston Astros, Cincinnati Reds
Team W L Pct GB Home Away RS RA Diff Strk L10
Houston Astros75720.510+16.037-3838-34662702-40W16-4
Cincinnati Reds69770.473+21.536-3833-39611733-122L35-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Houston Astros vs Cincinnati Reds MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, May 10th, 2026 at 1:40 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Houston Astros vs Cincinnati Reds Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Houston Astros vs Cincinnati Reds Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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