The Astros will play the Cardinals on Friday, March 13th, 2026. Your timezone's first pitch time is 6:05 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Astros at Cardinals Odds
| Underdog St. Louis Cardinals | Favorite Houston Astros |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite Houston Astros |
|---|---|
Matchup Odds FAQs
The Houston Astros are the -145 moneyline favorite at BetMGM and the St. Louis Cardinals are the +120 moneyline underdog at BetMGM.
The best over line is 8.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 8.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.
The Houston Astros are -1.5 +120 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -145 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Astros
Cardinals
6:05pm EDT | -145+120 |
- St. Louis Cardinals bettors risk $100 to win $120 at +120 odds. The implied probability for St. Louis Cardinals is 45.45%.
- Houston Astros bettors risk $100 to win $68.97 at -145 odds. The implied probability for Houston Astros is 59.18%.
Houston Astros at St. Louis Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Astros
Cardinals
6:05pm EDT | Pending BetMGM |
Houston Astros & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Houston Astros World Series Odds|
Team | BetMGM |
|---|---|
| Astros | +2200 Bet |
|
Team | BetMGM |
|---|---|
| Cardinals | +25000 Bet |
Houston Astros & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Houston Astros | 0 | 0 | 0.000 | 0.0 | 0-0 | 0-0 | 0 | 0 | 0 | - | 0 |
| St. Louis Cardinals | 0 | 0 | 0.000 | 0.0 | 0-0 | 0-0 | 0 | 0 | 0 | - | 0 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Houston Astros vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Friday, March 13th, 2026 at 6:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Houston Astros vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Houston Astros vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other March 13, 2026 MLB Games
- New York Yankees vs Atlanta Braves - 1:05pm EDT
- Tampa Bay Rays vs Boston Red Sox - 1:05pm EDT
- Baltimore Orioles vs Philadelphia Phillies - 1:05pm EDT
- Minnesota Twins vs Toronto Blue Jays - 1:07pm EDT
- Chicago Cubs vs Chicago White Sox - 4:05pm EDT
- Cleveland Guardians vs Los Angeles Angels - 4:10pm EDT
- Texas Rangers vs Colorado Rockies - 4:10pm EDT
- Pittsburgh Pirates vs Detroit Tigers - 6:05pm EDT
- Arizona Diamondbacks vs Kansas City Royals - 9:05pm EDT
- Los Angeles Dodgers vs Seattle Mariners - 9:10pm EDT