Los Angeles Angels vs Cleveland Guardians Odds

The Angels will play the Guardians on Friday, March 6th, 2026. Your timezone's first pitch time is 3:05 pm EST. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Best Angels at Guardians Odds


Best Moneyline Betting Odds
Underdog

Los Angeles Angels
Favorite

Cleveland Guardians
The Cleveland Guardians are the -150 moneyline favorite. Risk $150 to win $100 on the Cleveland Guardians at BetMGM. The Los Angeles Angels are the +130 underdog at BetMGM. Risk $100 to win $130 on the Los Angeles Angels. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 10.5 runs. Risk $115 to win $100. BetMGM has the best under line of 10.5 runs. Risk $105 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

Los Angeles Angels
Favorite

Cleveland Guardians
The Cleveland Guardians have a -1.5 +120 run line at BetMGM OH. They are the run line favorite in this matchup. The Los Angeles Angels have a +1.5 -140 run line at BetMGM OH. The Los Angeles Angels are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Los Angeles Angels vs Cleveland Guardians MLB game on Friday, March 6th, 2026?

The Cleveland Guardians are the -150 moneyline favorite at BetMGM and the Los Angeles Angels are the +130 moneyline underdog at BetMGM.

What is the over-under total line for the Los Angeles Angels vs Cleveland Guardians MLB game on Friday, March 6th, 2026?

The best over line is 10.5 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 10.5 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.

What is the run line for the Los Angeles Angels vs Cleveland Guardians MLB game on Friday, March 6th, 2026?

The Cleveland Guardians are -1.5 +120 run line favorites at BetMGM, while the Los Angeles Angels are +1.5 -140 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Angels
Guardians
3/06/26 3:05pm EST
+130-150
Bet $100 at BetMGM Ohio
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Possible Moneyline Outcomes
  • Los Angeles Angels bettors risk $100 to win $130 at +130 odds. The implied probability for Los Angeles Angels is 43.48%.
  • Cleveland Guardians bettors risk $100 to win $66.67 at -150 odds. The implied probability for Cleveland Guardians is 60%.

Los Angeles Angels at Cleveland Guardians Prop Bets

MLB Prop Bets
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Angels
Guardians
3/06/26 3:05pm EST
Pending BetMGM

Los Angeles Angels & Cleveland Guardians Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Los Angeles Angels World Series Odds
2026 Los Angeles Angels World Series Odds

Team
BetMGM Sports Betting BetMGM
Angels
+25000
Bet
Cleveland Guardians World Series Odds
2026 Cleveland Guardians World Series Odds

Team
BetMGM Sports Betting BetMGM
Guardians
+6600
Bet

Los Angeles Angels & Cleveland Guardians Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2026 MLB Regular Season Standings - Los Angeles Angels, Cleveland Guardians
Team W L Pct GB Home Away RS RA Diff Strk L10
Cleveland Guardians000.0000.00-00-0000-0
Los Angeles Angels000.0000.00-00-0000-0

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Los Angeles Angels vs Cleveland Guardians MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, March 6th, 2026 at 3:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the Los Angeles Angels vs Cleveland Guardians Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Los Angeles Angels vs Cleveland Guardians Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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