Milwaukee Brewers vs San Diego Padres Odds

The Brewers will play the Padres on Wednesday, September 24th, 2025. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

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Best Brewers at Padres Odds

**Best Moneyline Betting Odds**
Underdog Milwaukee Brewers	Favorite San Diego Padres
+110 BetMGM Bet	-130 BetMGM Bet

The San Diego Padres are the -130 moneyline favorite. Risk $130 to win $100 on the San Diego Padres at BetMGM. The Milwaukee Brewers are the +110 underdog at BetMGM. Risk $100 to win $110 on the Milwaukee Brewers. Learn more about how to bet on money lines.

**Best Total Betting Odds**
Over	Under
8 o +100 BetMGM Bet	8 u -120 BetMGM Bet

BetMGM has the best over line of 8 runs. Risk $100 to win $100. BetMGM has the best under line of 8 runs. Risk $120 to win $100. Our tutorial explains more about total bets.

**Best Run Line Betting Odds**
Underdog Milwaukee Brewers	Favorite San Diego Padres
+1.5 -200 BetMGM Bet	-1.5 +165 BetMGM Bet

The San Diego Padres have a -1.5 +165 run line at BetMGM OH. They are the run line favorite in this matchup. The Milwaukee Brewers have a +1.5 -200 run line at BetMGM OH. The Milwaukee Brewers are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Milwaukee Brewers vs San Diego Padres MLB game on Wednesday, September 24th, 2025?

The San Diego Padres are the -130 moneyline favorite at BetMGM and the Milwaukee Brewers are the +110 moneyline underdog at BetMGM.

What is the over-under total line for the Milwaukee Brewers vs San Diego Padres MLB game on Wednesday, September 24th, 2025?

The best over line is 8 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 8 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.

What is the run line for the Milwaukee Brewers vs San Diego Padres MLB game on Wednesday, September 24th, 2025?

The San Diego Padres are -1.5 +165 run line favorites at BetMGM, while the Milwaukee Brewers are +1.5 -200 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained
Game	BetMGM Bet
Brewers Padres 9/24/25 4:10pm EDT	+110 -130

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Possible Moneyline Outcomes

Milwaukee Brewers bettors risk $100 to win $110 at +110 odds. The implied probability for Milwaukee Brewers is 47.62%.
San Diego Padres bettors risk $100 to win $76.92 at -130 odds. The implied probability for San Diego Padres is 56.52%.

Milwaukee Brewers at San Diego Padres Prop Bets

MLB Prop Bets
+ Displays more odds
	BetMGM Bet
Brewers Padres First Team to Score 9/24/25 4:10pm EDT	-145 +110 Bet
Brewers Padres Tie 1st Inning Winner 9/24/25 4:10pm EDT	+310 +290 -140 Bet
Brewers Padres Tie First 3 Innings Winner 9/24/25 4:10pm EDT	+154 +130 +280 Bet
Brewers Padres To Extra Innings 9/24/25 4:10pm EDT	Yes +750 No -1200 Bet
	BetMGM
Brewers Padres 1st Team to Score Will Win 9/24/25 4:10pm EDT	Yes -250 No +190 Bet
Brewers Total Runs MIL at SDG 9/24/25 4:10pm EDT	3.5 o -125 3.5 u -105 Bet
Padres Total Runs MIL at SDG 9/24/25 4:10pm EDT	3.5 o -145 3.5 u +110 Bet
Dylan Cease Strikeouts Thrown MIL at SDG 9/24/25 4:10pm EDT	5.5 o -150 5.5 u +110 Bet

Milwaukee Brewers & San Diego Padres Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Milwaukee Brewers World Series Odds

No World Series TM Milwaukee Brewers YR: futures available

San Diego Padres World Series Odds

No World Series TM San Diego Padres YR: futures available

Milwaukee Brewers & San Diego Padres Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Milwaukee Brewers, San Diego Padres
Team	W	L	Pct	GB	Home	Away	RS	RA	Diff	Strk	L10
* - Milwaukee Brewers	97	65	0.599	0.0	52-29	45-36	806	634	+172	W1	4-6
y - San Diego Padres	90	72	0.556	+7.0	52-29	38-43	702	621	+81	W3	7-3

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Milwaukee Brewers vs San Diego Padres MLB Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, September 24th, 2025 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's MLB page, look for the Milwaukee Brewers vs San Diego Padres Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Milwaukee Brewers vs San Diego Padres Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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