San Francisco Giants vs San Diego Padres MLB Betting Lines

Odds Preview 2994

The Giants will play the Padres on Thursday, September 23rd, 2021 at 4:10 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers

• Giants - L. Webb - R
• Padres - Y. Darvish - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

Best Money Line Bets

Underdog San Diego Padres	Favorite San Francisco Giants
-101 Sb3gen1	-109 Sb3gen1
-105 Sb3gen2	-115 Sb3gen2
-105 Sb3gen3	-115 Sb3gen3

Here are money lines for the outright winner. Favorite San Francisco Giants has a minus value. Lay $109 at Sb3gen1 to win $100. Underdog San Diego Padres has a negative value. Risk $101 at Sb3gen1 to win $100.

Best Over and Under Total Lines

Over	Under
7.5o -108 Sb3gen1	7.5u -105 Sb3gen2
7.5o -115 Sb3gen2	7.5u -105 Sb3gen3
7.5o -115 Sb3gen3	7.5u -112 Sb3gen1

The over under line estimates the combined total of each team's final score. Sb3gen1 has the best over line of 7.5 points laying $108 to win $100. Sb3gen2 has the best under line of 7.5 u -105.

Best Underdog and Favorite Run Line Bets

Underdog San Diego Padres	Favorite San Francisco Giants
+1.5 -170 Sb3gen1	-1.5 +150 Sb3gen1
+1.5 -170 Sb3gen2	-1.5 +145 Sb3gen2
+1.5 -170 Sb3gen3	-1.5 +145 Sb3gen3

SportsBetting3.com has analyzed the latest lines. Review our "Best Run Line Bets" table above to smash the books this Thursday. Sb3gen1 has the best favorite San Francisco Giants run line at -1.5 points. Sb3gen1 has the best underdog San Diego Padres run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Francisco Giants World Series Odds

Outcome	SB3Gen
San Francisco Giants	+350

Cached 2021-10-24 00:48:19
San Diego Padres World Series Odds

Outcome	SB3Gen

Cached 2021-10-24 00:48:19

Team Standings

Season Standings

Team	W	L	Pct	GB	Home	Away	Strk	L10
San Francisco Giants	107	55	0.660	0.0	107-55	54-27	W1	94-48
San Diego Padres	79	83	0.488	28.0	79-83	45-36	L1	65-77

San Francisco Giants Batting Stats

2021 San Francisco Giants Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Mike Yastrzemski CF	141	75	105	25	71	51	131	0.224
Brandon Crawford SS	139	79	144	24	90	56	105	0.298
Wilmer Flores 1B	139	57	102	18	53	41	56	0.262
Austin Slater RF	129	39	66	12	32	28	84	0.241
Darin Ruf 1B	118	41	71	16	43	46	87	0.271
Buster Posey C	115	68	120	18	56	56	87	0.304
Alex Dickerson LF	111	37	66	13	38	23	76	0.233
LaMonte Wade Jr. LF	110	52	85	18	56	33	89	0.253
Steven Duggar CF	107	45	69	8	35	27	88	0.257
Donovan Solano 2B	101	35	86	7	31	25	58	0.280
Brandon Belt 1B	97	65	89	29	59	48	103	0.274
Evan Longoria 3B	81	45	66	13	46	35	68	0.261

San Diego Padres Batting Stats

2021 San Diego Padres Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Tommy Pham LF	155	74	109	15	49	78	128	0.229
Manny Machado 3B	153	92	157	28	106	63	102	0.278
Jake Cronenworth 2B	152	94	151	21	71	55	90	0.266
Eric Hosmer 1B	151	53	137	12	65	48	99	0.269
Wil Myers RF	146	56	113	17	63	54	141	0.256
Jurickson Profar LF	137	47	80	4	33	49	65	0.227
Trent Grisham CF	132	61	112	15	62	54	119	0.242
Fernando Tatis Jr. SS	130	99	135	42	97	62	153	0.282
Ha-Seong Kim 2B	117	27	54	8	34	22	71	0.202
Victor Caratini C	116	33	71	7	39	35	82	0.227
Tim Hill RP	78	0	0	0	0	0	0	0.000
Austin Adams RP	65	0	0	0	0	0	0	0.000

San Francisco Giants Pitching Stats

2021 San Francisco Giants Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Kevin Gausman SP	34	14	6	0	0	192.0	227	1.04	2.81
Anthony DeSclafani SP	31	13	7	0	0	167.2	152	1.09	3.17
Logan Webb SP	27	11	3	0	1	148.1	158	1.11	3.03
Alex Wood SP	26	10	4	0	0	138.2	152	1.18	3.83
Tyler Rogers RP	80	7	1	13	30	81.0	55	1.07	2.22
Johnny Cueto SP	22	7	7	0	0	114.2	98	1.37	4.08
Jarlin Garcia RP	58	6	3	1	11	68.2	68	0.96	2.62
Jose Alvarez RP	67	5	2	0	8	64.2	42	1.11	2.37
Camilo Doval RP	29	5	1	3	6	27.0	37	1.04	3.00
Zack Littell RP	63	4	0	2	7	61.2	63	1.14	2.92
Dominic Leone RP	57	4	5	2	15	53.2	50	1.10	1.51
Tony Watson RP	26	4	1	0	7	24.1	19	0.78	2.96

San Diego Padres Pitching Stats

2021 San Diego Padres Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Joe Musgrove SP	40	11	9	0	0	181.1	203	1.08	3.18
Yu Darvish SP	30	8	11	0	0	166.1	199	1.09	4.22
Blake Snell SP	27	7	6	0	0	128.2	170	1.32	4.20
Chris Paddack SP	23	7	7	0	0	108.1	99	1.26	5.07
Tim Hill RP	78	6	6	1	19	59.2	56	1.24	3.62
Craig Stammen RP	67	6	3	1	7	88.1	83	1.04	3.06
Emilio Pagan RP	67	4	3	0	17	63.1	69	1.17	4.83
Mark Melancon RP	64	4	3	39	0	64.2	59	1.22	2.23
Ryan Weathers SP	30	4	7	1	0	94.2	72	1.38	5.32
Austin Adams RP	65	3	2	0	11	52.2	76	1.20	4.10
Pierce Johnson RP	63	3	4	0	12	58.2	77	1.26	3.22
Nabil Crismatt RP	45	3	1	0	3	81.1	71	1.36	3.76

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