Pittsburgh Pirates vs San Diego Padres MLB Betting Lines

Odds Preview 1110

The Pirates will play the Padres on Wednesday, May 5th, 2021 at 8:10 pm ET. Check network listings or your nearest streaming app for coverage. Our opening pitch flys at Eastern Standard, make sure you adjust for your local timezone.

Matchup Pitchers

• Pirates - J. Brubaker - R
• Padres - Y. Darvish - R

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.

Best Money Line Bets

Underdog Pittsburgh Pirates	Favorite San Diego Padres
+202 Betonline	-223 Betonline
+200 Bovada	-223 Gtbets
+195 Mybookie	-235 Bovada
+193 Gtbets	-245 Mybookie

Here are money lines for the outright winner. Favorite San Diego Padres has a minus value. Lay $223 at Betonline to win $100. Underdog Pittsburgh Pirates has a positive value. Risk $100 at Betonline to win $202.

Best Over and Under Total Lines

Over	Under
6.5o -105 Bovada	6.5u -115 Bovada
6.5o -105 Betonline	6.5u -115 Betonline
6.5o -105 Mybookie	6.5u -115 Mybookie
6.5o -105 Gtbets	6.5u -115 Gtbets

The over under line estimates the combined total of each team's final score. Bovada has the best over line of 6.5 points laying $105 to win $100. Bovada has the best under line of 6.5 u -115.

Best Underdog and Favorite Run Line Bets

Underdog Pittsburgh Pirates	Favorite San Diego Padres
+1.5 -120 Mybookie	-1.5 +105 Bovada
+1.5 -125 Bovada	-1.5 +105 Betonline
+1.5 -125 Betonline	-1.5 +105 Gtbets
+1.5 -125 Gtbets	-1.5 +100 Mybookie

SportsBetting3.com has analyzed the latest lines from Bovada, Betonline, and Mybookie. Review our "Best Run Line Bets" table above to smash the books this Wednesday. Bovada has the best favorite San Diego Padres run line at -1.5 points. Mybookie has the best underdog Pittsburgh Pirates run line at +1.5 points.

Review our point spread betting tutorial and video for more information.

MLB World Series Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament here. See past Championship results and learn how to bet World Series teasers, props and parlays.

Pittsburgh Pirates World Series Odds

Outcome	Bovada
Pittsburgh Pirates	+25000

Cached 2021-05-16 17:39:59
San Diego Padres World Series Odds

Outcome	Bovada
San Diego Padres	+850

Cached 2021-05-16 17:39:59

Team Standings

Season Standings

Team	W	L	Pct	GB	Home	Away	Strk	L10
Pittsburgh Pirates	17	22	0.436	7.0	8-10	9-12	W2	4-6
San Diego Padres	23	17	0.575	1.5	11-10	12-7	W2	6-4

Pittsburgh Pirates Batting Stats

2021 Pittsburgh Pirates Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Adam Frazier 2B	38	20	49	1	13	14	19	0.318
Bryan Reynolds LF	37	24	40	3	15	20	32	0.301
Kevin Newman SS	36	11	28	1	8	5	10	0.209
Erik Gonzalez 2B	36	10	25	2	15	3	23	0.202
Colin Moran 3B	32	10	33	4	19	10	34	0.297
Jacob Stallings C	32	10	25	3	15	17	22	0.255
Phillip Evans 3B	32	14	24	4	8	14	29	0.216
Gregory Polanco RF	29	11	20	3	7	11	32	0.208
Wilmer Difo SS	29	5	14	1	6	2	19	0.241
Dustin Fowler CF	18	3	7	0	2	3	20	0.171
Richard Rodriguez RP	17	0	0	0	0	0	0	0.000
Chris Stratton RP	16	0	0	0	0	0	0	0.000

San Diego Padres Batting Stats

2021 San Diego Padres Batting
Top 12 by Games Played

Player	GP	R	H	HR	RBI	BB	SO	AVG
Jake Cronenworth 2B	40	24	43	3	11	17	22	0.289
Manny Machado 3B	39	21	34	5	26	23	29	0.236
Tommy Pham LF	37	9	19	1	8	18	24	0.192
Wil Myers RF	35	15	27	4	15	14	27	0.255
Eric Hosmer 1B	35	12	40	4	21	13	19	0.305
Jurickson Profar LF	34	15	25	1	10	17	21	0.234
Ha-Seong Kim 2B	32	8	16	2	8	3	21	0.195
Trent Grisham CF	31	19	36	5	12	16	33	0.305
Victor Caratini C	29	10	20	3	17	12	27	0.247
Fernando Tatis Jr. SS	26	23	23	9	14	11	29	0.240
Jorge Mateo SS	22	2	9	1	5	1	10	0.250
Tim Hill RP	17	0	0	0	0	0	0	0.000

Pittsburgh Pirates Pitching Stats

2021 Pittsburgh Pirates Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Tyler Anderson SP	8	3	3	0	0	46.1	44	1.10	3.50
JT Brubaker SP	7	3	2	0	0	38.1	41	1.12	2.58
Sam Howard RP	19	2	2	0	7	13.1	21	1.05	3.38
Richard Rodriguez RP	17	2	0	6	0	17.0	14	0.41	0.53
Mitch Keller SP	7	2	4	0	0	27.2	26	1.81	7.81
Clay Holmes RP	17	1	0	0	1	17.2	17	1.25	4.08
Chris Stratton RP	16	1	0	0	4	19.1	19	1.24	4.19
Duane Underwood Jr. RP	15	1	2	0	1	20.2	26	1.35	4.79
Luis Oviedo SP	8	1	1	0	0	12.2	11	1.58	7.82
Trevor Cahill SP	7	1	4	0	0	34.2	27	1.41	5.97
David Bednar RP	17	0	0	0	4	15.1	19	0.91	2.35
Kyle Crick RP	12	0	0	0	3	11.1	10	0.62	1.59

San Diego Padres Pitching Stats

2021 San Diego Padres Pitching
Top 12 by Wins and Games Played

Player	GP	W	L	SV	HLD	IP	K	WHIP	ERA
Emilio Pagan RP	18	3	0	0	4	16.0	23	1.38	3.38
Joe Musgrove SP	8	3	4	0	0	44.0	59	0.95	2.86
Yu Darvish SP	8	3	1	0	0	47.2	59	0.92	2.08
Tim Hill RP	20	2	2	0	6	17.0	19	1.18	2.65
Craig Stammen RP	16	2	1	1	2	24.0	25	0.92	1.88
Keone Kela RP	12	2	2	0	1	10.2	13	1.31	5.06
Ryan Weathers SP	8	2	1	1	0	22.1	20	0.72	0.81
Miguel Diaz RP	3	2	0	0	0	8.0	7	0.88	1.13
Blake Snell SP	8	1	0	0	0	34.1	49	1.54	4.19
Chris Paddack SP	7	1	3	0	0	30.1	28	1.35	4.45
Nabil Crismatt RP	7	1	1	0	0	13.2	11	1.46	2.63
Aaron Northcraft SP	4	1	0	0	0	6.0	5	1.67	3.00

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