San Diego Padres vs Kansas City Royals Odds

The Padres will play the Royals on Saturday, February 21st, 2026. Your timezone's first pitch time is 3:05 pm EST. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


Bonus
BetMGM Sportsbook#1 BetMGM
REVIEW
New Customers - Up to $1500 Paid Back in Bonus Bets
Bonus Bets Expire in 7 Days
One new customer offer/Add'l Terms

Bet Now
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Table of Contents

Best Padres at Royals Odds


Best Moneyline Betting Odds
Underdog

San Diego Padres
Favorite

Kansas City Royals
The Kansas City Royals are the -135 moneyline favorite. Risk $135 to win $100 on the Kansas City Royals at BetMGM. The San Diego Padres are the +115 underdog at BetMGM. Risk $100 to win $115 on the San Diego Padres. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 10.5 runs. Risk $100 to win $100. BetMGM has the best under line of 10.5 runs. Risk $120 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

San Diego Padres
Favorite

Kansas City Royals
The Kansas City Royals have a -1.5 +135 run line at BetMGM OH. They are the run line favorite in this matchup. The San Diego Padres have a +1.5 -165 run line at BetMGM OH. The San Diego Padres are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the San Diego Padres vs Kansas City Royals MLB game on Saturday, February 21st, 2026?

The Kansas City Royals are the -135 moneyline favorite at BetMGM and the San Diego Padres are the +115 moneyline underdog at BetMGM.

What is the over-under total line for the San Diego Padres vs Kansas City Royals MLB game on Saturday, February 21st, 2026?

The best over line is 10.5 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 10.5 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.

What is the run line for the San Diego Padres vs Kansas City Royals MLB game on Saturday, February 21st, 2026?

The Kansas City Royals are -1.5 +135 run line favorites at BetMGM, while the San Diego Padres are +1.5 -165 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Padres
Royals
2/21/26 3:05pm EST
+115-135
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966
Possible Moneyline Outcomes
  • San Diego Padres bettors risk $100 to win $115 at +115 odds. The implied probability for San Diego Padres is 46.51%.
  • Kansas City Royals bettors risk $100 to win $74.07 at -135 odds. The implied probability for Kansas City Royals is 57.45%.

San Diego Padres at Kansas City Royals Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Padres
Royals
2/21/26 3:05pm EST
Pending BetMGM

San Diego Padres & Kansas City Royals Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Diego Padres World Series Odds
2026 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM
Padres
+2800
Bet
Kansas City Royals World Series Odds
2026 Kansas City Royals World Series Odds

Team
BetMGM Sports Betting BetMGM
Royals
+3500
Bet

San Diego Padres & Kansas City Royals Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Diego Padres, Kansas City Royals
Team W L Pct GB Home Away RS RA Diff Strk L10
y - San Diego Padres90720.556+7.052-2938-43702621+81W37-3
e - Kansas City Royals82800.506+15.043-3839-42651637+14W26-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Diego Padres vs Kansas City Royals MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Saturday, February 21st, 2026 at 3:05 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the San Diego Padres vs Kansas City Royals Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs Kansas City Royals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other February 21, 2026 MLB Games

Odds Preview 14562